1I2TA

X-ray structure of the human hyperplastic discs protein: an ortholog of the c-terminal domain of poly(a)-binding protein
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
61
structure length
61
Chain Sequence
HRQALGERLYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Ligase
molecule keywords HYD PROTEIN
publication title X-ray structure of the human hyperplastic discs protein: an ortholog of the C-terminal domain of poly(A)-binding protein.
pubmed doi rcsb
source organism Homo sapiens
total genus 24
structure length 61
sequence length 61
ec nomenclature ec 2.3.2.26: HECT-type E3 ubiquitin transferase.
pdb deposition date 2001-02-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1900.10 Mainly Alpha Orthogonal Bundle c-terminal domain of poly(a) binding protein c-terminal domain of poly(a) binding protein 1i2tA00
3KTPA 1I2TA 3PTHA 3KUSA 1NMRA 3PKNA 2X04A 1JH4A 1JGNA 2O4TA 4IVEA 1G9LA 3KUJA 3KURA 2O3LA 1IFWA 2HH6A 3KTRA 3KUIA 2RQHB 3KUTA 3NTWA 2RQGB 2DYDA
chains in the Genus database with same CATH superfamily
3KTPA 1I2TA 3PTHA 2LKLA 3KUSA 1GYZA 1NMRA 3PKNA 2X04A 1JH4A 1JGNA 2O4TA 4IVEA 1G9LA 3KUJA 3KURA 2O3LA 3M92A 1IFWA 2HH6A 3KTRA 3KUIA 2RQHB 3KUTA 4KXFB 3NTWA 2RQGB 2DYDA 2GHJA
chains in the Genus database with same CATH topology
3KTPA 1I2TA 3PTHA 2LKLA 3KUSA 1NMRA 3PKNA 2X04A 1JH4A 1JGNA 2O4TA 4IVEA 1G9LA 3KUJA 3KURA 2O3LA 3M92A 1IFWA 2HH6A 3KTRA 3KUIA 2RQHB 3KUTA 4KXFB 3NTWA 2RQGB 2DYDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KTP A;  1I2T A;  3PTH A;  3KUS A;  1NMR A;  3PKN A;  2X04 A;  1JH4 A;  1JGN A;  2O4T A;  4IVE A;  1G9L A;  3KUJ A;  3KUR A;  2O3L A;  1IFW A;  2HH6 A;  3KTR A;  3KUI A;  2RQH B;  3KUT A;  3NTW A;  2RQG B;  2DYD A; 
#chains in the Genus database with same CATH topology
 3KTP A;  1I2T A;  3PTH A;  2LKL A;  3KUS A;  1GYZ A;  1NMR A;  3PKN A;  2X04 A;  1JH4 A;  1JGN A;  2O4T A;  4IVE A;  1G9L A;  3KUJ A;  3KUR A;  2O3L A;  3M92 A;  1IFW A;  2HH6 A;  3KTR A;  3KUI A;  2RQH B;  3KUT A;  4KXF B;  3NTW A;  2RQG B;  2DYD A;  2GHJ A; 
#chains in the Genus database with same CATH homology
 3KTP A;  1I2T A;  3PTH A;  2LKL A;  3KUS A;  1NMR A;  3PKN A;  2X04 A;  1JH4 A;  1JGN A;  2O4T A;  4IVE A;  1G9L A;  3KUJ A;  3KUR A;  2O3L A;  3M92 A;  1IFW A;  2HH6 A;  3KTR A;  3KUI A;  2RQH B;  3KUT A;  4KXF B;  3NTW A;  2RQG B;  2DYD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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