1ID4A

Crystal structure of the catalytic site mutant (h157q) of the human cytomegalovirus protease
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
248
structure length
208
Chain Sequence
QAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLALPLNINHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKVVEFLSGSYAGLSLSSRFKQVALCSVGRRRGTLAVYGRDPEWVTQRFPDLTAADRDGLRAQWQGDPFRSDSYGLLGNSVDALYIRERLPKLRYDKQLVGVTERESYVKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords CAPSID PROTEIN P40: ASSEMBLIN PROTEASE
publication title Investigating the role of histidine 157 in the catalytic activity of human cytomegalovirus protease.
pubmed doi rcsb
source organism Human herpesvirus 5
total genus 61
structure length 208
sequence length 248
chains with identical sequence B
ec nomenclature ec 3.4.21.97: Assemblin.
pdb deposition date 2001-04-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.20.16.10 Alpha Beta Alpha-Beta Barrel Serine Protease, Human Cytomegalovirus Protease; Chain A Herpesvirus/Caudovirus protease domain 1id4A00
1IEGA 2WPOA 1ID4A 1IEDA 1FL1A 1NKMA 1NJUA 1NKKA 1NJTA 4P2TA 4V0TA 1IEFA 1VZVA 3NJQB 4P3HA 2PBKA 1CMVA 4V08A 1IECA 1JQ6A 1LAYA 1JQ7A 4V07A 4CX8A 1O6EA 1AT3A 1WPOA 3NJQA
chains in the Genus database with same CATH superfamily
1IEGA 2WPOA 1ID4A 1IEDA 1FL1A 1NKMA 1NJUA 1NKKA 1NJTA 4P2TA 4V0TA 1IEFA 1VZVA 3NJQB 4P3HA 2PBKA 1CMVA 4V08A 1IECA 1JQ6A 1LAYA 1JQ7A 4V07A 4CX8A 1O6EA 1AT3A 1WPOA 3NJQA
chains in the Genus database with same CATH topology
1IEGA 2WPOA 1ID4A 1IEDA 1FL1A 1NKMA 1NJUA 1NKKA 1NJTA 4P2TA 4V0TA 1IEFA 1VZVA 3NJQB 4P3HA 2PBKA 1CMVA 4V08A 1IECA 1JQ6A 1LAYA 1JQ7A 4V07A 4CX8A 1O6EA 1AT3A 1WPOA 3NJQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IEG A;  2WPO A;  1ID4 A;  1IED A;  1FL1 A;  1NKM A;  1NJU A;  1NKK A;  1NJT A;  4P2T A;  4V0T A;  1IEF A;  1VZV A;  3NJQ B;  4P3H A;  2PBK A;  1CMV A;  4V08 A;  1IEC A;  1JQ6 A;  1LAY A;  1JQ7 A;  4V07 A;  4CX8 A;  1O6E A;  1AT3 A;  1WPO A;  3NJQ A; 
#chains in the Genus database with same CATH topology
 1IEG A;  2WPO A;  1ID4 A;  1IED A;  1FL1 A;  1NKM A;  1NJU A;  1NKK A;  1NJT A;  4P2T A;  4V0T A;  1IEF A;  1VZV A;  3NJQ B;  4P3H A;  2PBK A;  1CMV A;  4V08 A;  1IEC A;  1JQ6 A;  1LAY A;  1JQ7 A;  4V07 A;  4CX8 A;  1O6E A;  1AT3 A;  1WPO A;  3NJQ A; 
#chains in the Genus database with same CATH homology
 1IEG A;  2WPO A;  1ID4 A;  1IED A;  1FL1 A;  1NKM A;  1NJU A;  1NKK A;  1NJT A;  4P2T A;  4V0T A;  1IEF A;  1VZV A;  3NJQ B;  4P3H A;  2PBK A;  1CMV A;  4V08 A;  1IEC A;  1JQ6 A;  1LAY A;  1JQ7 A;  4V07 A;  4CX8 A;  1O6E A;  1AT3 A;  1WPO A;  3NJQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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