1IEDA

Crystal structure of the catalytic site mutant (h157e) of the human cytomegalovirus protease
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
248
structure length
214
Chain Sequence
QAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAVALPLNINHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKVVEFLSGSYAGLSLSSRRTPFKEVALCSVGRRRGTLAVYGRDPEWVTQRFPDLTAADRDGLRAQWQGDPFRSDSYGLLGNSVDALYIRERLPKLRYDKQLVGVTERESYVKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords CAPSID PROTEIN P40: ASSEMBLIN PROTEASE
publication title Investigating the role of histidine 157 in the catalytic activity of human cytomegalovirus protease.
pubmed doi rcsb
source organism Human herpesvirus 5
total genus 61
structure length 214
sequence length 248
chains with identical sequence B
ec nomenclature ec 3.4.21.97: Assemblin.
pdb deposition date 2001-04-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.20.16.10 Alpha Beta Alpha-Beta Barrel Serine Protease, Human Cytomegalovirus Protease; Chain A Herpesvirus/Caudovirus protease domain 1iedA00
1IEFA 1NJUA 1WPOA 4V07A 3NJQB 1FL1A 4P3HA 2WPOA 1ID4A 4V08A 1IEDA 4V0TA 1AT3A 1VZVA 3NJQA 4P2TA 1IECA 2PBKA 1LAYA 1O6EA 1CMVA 1IEGA 1JQ7A 1NKKA 1NKMA 1NJTA 1JQ6A 4CX8A
chains in the Genus database with same CATH superfamily
1IEFA 1NJUA 1WPOA 4V07A 3NJQB 1FL1A 4P3HA 2WPOA 1ID4A 4V08A 1IEDA 4V0TA 1AT3A 1VZVA 3NJQA 4P2TA 1IECA 2PBKA 1LAYA 1O6EA 1CMVA 1IEGA 1JQ7A 1NKKA 1NKMA 1NJTA 1JQ6A 4CX8A
chains in the Genus database with same CATH topology
1IEFA 1NJUA 1WPOA 4V07A 3NJQB 1FL1A 4P3HA 2WPOA 1ID4A 4V08A 1IEDA 4V0TA 1AT3A 1VZVA 3NJQA 4P2TA 1IECA 2PBKA 1LAYA 1O6EA 1CMVA 1IEGA 1JQ7A 1NKKA 1NKMA 1NJTA 1JQ6A 4CX8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IEF A;  1NJU A;  1WPO A;  4V07 A;  3NJQ B;  1FL1 A;  4P3H A;  2WPO A;  1ID4 A;  4V08 A;  1IED A;  4V0T A;  1AT3 A;  1VZV A;  3NJQ A;  4P2T A;  1IEC A;  2PBK A;  1LAY A;  1O6E A;  1CMV A;  1IEG A;  1JQ7 A;  1NKK A;  1NKM A;  1NJT A;  1JQ6 A;  4CX8 A; 
#chains in the Genus database with same CATH topology
 1IEF A;  1NJU A;  1WPO A;  4V07 A;  3NJQ B;  1FL1 A;  4P3H A;  2WPO A;  1ID4 A;  4V08 A;  1IED A;  4V0T A;  1AT3 A;  1VZV A;  3NJQ A;  4P2T A;  1IEC A;  2PBK A;  1LAY A;  1O6E A;  1CMV A;  1IEG A;  1JQ7 A;  1NKK A;  1NKM A;  1NJT A;  1JQ6 A;  4CX8 A; 
#chains in the Genus database with same CATH homology
 1IEF A;  1NJU A;  1WPO A;  4V07 A;  3NJQ B;  1FL1 A;  4P3H A;  2WPO A;  1ID4 A;  4V08 A;  1IED A;  4V0T A;  1AT3 A;  1VZV A;  3NJQ A;  4P2T A;  1IEC A;  2PBK A;  1LAY A;  1O6E A;  1CMV A;  1IEG A;  1JQ7 A;  1NKK A;  1NKM A;  1NJT A;  1JQ6 A;  4CX8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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