3NJQA

Crystal structure of kaposi's sarcoma-associated herpesvirus protease in complex with dimer disruptor
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
190
structure length
189
Chain Sequence
GLYVGGFVDVVSPKLEQELYLDPDQVTDYLPVTEPLPITIEHLPETEVGWTLGLFQVSHGIFCTGAITSPAFLELASRLADTSHVARAPVKNLPKEPLLEILHTWLPGLSLSSIHPRELSQTPSGPVFQHVSLCALGRRRGTVAVYGHDAEWVVSRFSSVSKSERAHILQHVSSCRLEDLSTPNFVSPL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Viral protein/inhibitor
molecule keywords ORF 17
publication title Enzyme inhibition by allosteric capture of an inactive conformation.
pubmed doi rcsb
source organism Human herpesvirus 8 type m
total genus 47
structure length 189
sequence length 190
ec nomenclature
pdb deposition date 2010-06-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.20.16.10 Alpha Beta Alpha-Beta Barrel Serine Protease, Human Cytomegalovirus Protease; Chain A Herpesvirus/Caudovirus protease domain 3njqA00
1IECA 1NKMA 1NJUA 4P3HA 1AT3A 4P2TA 2PBKA 1IEFA 1IEGA 4V0TA 1FL1A 1LAYA 4V07A 3NJQA 4CX8A 1JQ7A 1WPOA 3NJQB 1VZVA 1O6EA 4V08A 1NJTA 2WPOA 1NKKA 1IEDA 1ID4A 1JQ6A 1CMVA
chains in the Genus database with same CATH superfamily
1IECA 1NKMA 1NJUA 4P3HA 1AT3A 4P2TA 2PBKA 1IEFA 1IEGA 4V0TA 1FL1A 1LAYA 4V07A 3NJQA 4CX8A 1JQ7A 1WPOA 3NJQB 1VZVA 1O6EA 4V08A 1NJTA 2WPOA 1NKKA 1IEDA 1ID4A 1JQ6A 1CMVA
chains in the Genus database with same CATH topology
1IECA 1NKMA 1NJUA 4P3HA 1AT3A 4P2TA 2PBKA 1IEFA 1IEGA 4V0TA 1FL1A 1LAYA 4V07A 3NJQA 4CX8A 1JQ7A 1WPOA 3NJQB 1VZVA 1O6EA 4V08A 1NJTA 2WPOA 1NKKA 1IEDA 1ID4A 1JQ6A 1CMVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IEC A;  1NKM A;  1NJU A;  4P3H A;  1AT3 A;  4P2T A;  2PBK A;  1IEF A;  1IEG A;  4V0T A;  1FL1 A;  1LAY A;  4V07 A;  3NJQ A;  4CX8 A;  1JQ7 A;  1WPO A;  3NJQ B;  1VZV A;  1O6E A;  4V08 A;  1NJT A;  2WPO A;  1NKK A;  1IED A;  1ID4 A;  1JQ6 A;  1CMV A; 
#chains in the Genus database with same CATH topology
 1IEC A;  1NKM A;  1NJU A;  4P3H A;  1AT3 A;  4P2T A;  2PBK A;  1IEF A;  1IEG A;  4V0T A;  1FL1 A;  1LAY A;  4V07 A;  3NJQ A;  4CX8 A;  1JQ7 A;  1WPO A;  3NJQ B;  1VZV A;  1O6E A;  4V08 A;  1NJT A;  2WPO A;  1NKK A;  1IED A;  1ID4 A;  1JQ6 A;  1CMV A; 
#chains in the Genus database with same CATH homology
 1IEC A;  1NKM A;  1NJU A;  4P3H A;  1AT3 A;  4P2T A;  2PBK A;  1IEF A;  1IEG A;  4V0T A;  1FL1 A;  1LAY A;  4V07 A;  3NJQ A;  4CX8 A;  1JQ7 A;  1WPO A;  3NJQ B;  1VZV A;  1O6E A;  4V08 A;  1NJT A;  2WPO A;  1NKK A;  1IED A;  1ID4 A;  1JQ6 A;  1CMV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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