2WPOA

Hcmv protease inhibitor complex
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
253
structure length
230
Chain Sequence
DEQQSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAQLSVALPLNINHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKVVEFLSGSYAGLSLSSRRCDDVEQTTPFKHVALCSVGRRRGTLAVYGRDPEWVMQRFPDLTAADRDGLRAQWQSGDPFRSDSYGLLGNSVDAMYIRERLPKLRYDKQLVGVTERESYVKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor
molecule keywords HUMAN CYTOMEGALOVIRUS PROTEASE
publication title Conserved mode of peptidomimetic inhibition and substrate recognition of human cytomegalovirus protease.
pubmed doi rcsb
source organism Human herpesvirus 5
total genus 60
structure length 230
sequence length 253
chains with identical sequence B, C, D
ec nomenclature ec 3.4.21.97: Assemblin.
pdb deposition date 1998-08-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.20.16.10 Alpha Beta Alpha-Beta Barrel Serine Protease, Human Cytomegalovirus Protease; Chain A Herpesvirus/Caudovirus protease domain 2wpoA00
1ID4A 4V07A 1WPOA 1IECA 1AT3A 1NJUA 1NKMA 3NJQB 1CMVA 1IEGA 1FL1A 1IEDA 1NJTA 2PBKA 1JQ6A 2WPOA 1O6EA 4P2TA 4V0TA 1NKKA 4P3HA 4V08A 1JQ7A 4CX8A 1LAYA 1VZVA 3NJQA 1IEFA
chains in the Genus database with same CATH superfamily
1ID4A 4V07A 1WPOA 1IECA 1AT3A 1NJUA 1NKMA 3NJQB 1CMVA 1IEGA 1FL1A 1IEDA 1NJTA 2PBKA 1JQ6A 2WPOA 1O6EA 4P2TA 4V0TA 1NKKA 4P3HA 4V08A 1JQ7A 4CX8A 1LAYA 1VZVA 3NJQA 1IEFA
chains in the Genus database with same CATH topology
1ID4A 4V07A 1WPOA 1IECA 1AT3A 1NJUA 1NKMA 3NJQB 1CMVA 1IEGA 1FL1A 1IEDA 1NJTA 2PBKA 1JQ6A 2WPOA 1O6EA 4P2TA 4V0TA 1NKKA 4P3HA 4V08A 1JQ7A 4CX8A 1LAYA 1VZVA 3NJQA 1IEFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ID4 A;  4V07 A;  1WPO A;  1IEC A;  1AT3 A;  1NJU A;  1NKM A;  3NJQ B;  1CMV A;  1IEG A;  1FL1 A;  1IED A;  1NJT A;  2PBK A;  1JQ6 A;  2WPO A;  1O6E A;  4P2T A;  4V0T A;  1NKK A;  4P3H A;  4V08 A;  1JQ7 A;  4CX8 A;  1LAY A;  1VZV A;  3NJQ A;  1IEF A; 
#chains in the Genus database with same CATH topology
 1ID4 A;  4V07 A;  1WPO A;  1IEC A;  1AT3 A;  1NJU A;  1NKM A;  3NJQ B;  1CMV A;  1IEG A;  1FL1 A;  1IED A;  1NJT A;  2PBK A;  1JQ6 A;  2WPO A;  1O6E A;  4P2T A;  4V0T A;  1NKK A;  4P3H A;  4V08 A;  1JQ7 A;  4CX8 A;  1LAY A;  1VZV A;  3NJQ A;  1IEF A; 
#chains in the Genus database with same CATH homology
 1ID4 A;  4V07 A;  1WPO A;  1IEC A;  1AT3 A;  1NJU A;  1NKM A;  3NJQ B;  1CMV A;  1IEG A;  1FL1 A;  1IED A;  1NJT A;  2PBK A;  1JQ6 A;  2WPO A;  1O6E A;  4P2T A;  4V0T A;  1NKK A;  4P3H A;  4V08 A;  1JQ7 A;  4CX8 A;  1LAY A;  1VZV A;  3NJQ A;  1IEF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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