1NKKA

Complex structure of hcmv protease and a peptidomimetic inhibitor
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
253
structure length
222
Chain Sequence
DEQQSQAVAPVYVGGFLARYDQSPDEARLLLPRDVVEHWLHAQVALPLNINHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKVVEFLSGSYAGLSLSSRRTTPFKHVALCSVGRRRGTLAVYGRDPEWVTQRFPDLTAADRDGLRAQWQRGDPFRSDSYGLLGNSVDALYIRERLPKLRYDKQLVGVTERESYVKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Capsid protein P40
publication title Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease
pubmed doi rcsb
source organism Human herpesvirus 5
total genus 71
structure length 222
sequence length 253
chains with identical sequence B, C, D
ec nomenclature ec 3.4.21.97: Assemblin.
pdb deposition date 2003-01-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.20.16.10 Alpha Beta Alpha-Beta Barrel Serine Protease, Human Cytomegalovirus Protease; Chain A Herpesvirus/Caudovirus protease domain 1nkkA00
4CX8A 1NKKA 1VZVA 4P3HA 1IEGA 4V07A 4P2TA 4V08A 1JQ6A 1ID4A 2WPOA 1IEDA 1NJUA 1IEFA 1NKMA 2PBKA 1JQ7A 1NJTA 1CMVA 1O6EA 1WPOA 1AT3A 1IECA 4V0TA 1LAYA 3NJQA 1FL1A 3NJQB
chains in the Genus database with same CATH superfamily
4CX8A 1NKKA 1VZVA 4P3HA 1IEGA 4V07A 4P2TA 4V08A 1JQ6A 1ID4A 2WPOA 1IEDA 1NJUA 1IEFA 1NKMA 2PBKA 1JQ7A 1NJTA 1CMVA 1O6EA 1WPOA 1AT3A 1IECA 4V0TA 1LAYA 3NJQA 1FL1A 3NJQB
chains in the Genus database with same CATH topology
4CX8A 1NKKA 1VZVA 4P3HA 1IEGA 4V07A 4P2TA 4V08A 1JQ6A 1ID4A 2WPOA 1IEDA 1NJUA 1IEFA 1NKMA 2PBKA 1JQ7A 1NJTA 1CMVA 1O6EA 1WPOA 1AT3A 1IECA 4V0TA 1LAYA 3NJQA 1FL1A 3NJQB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CX8 A;  1NKK A;  1VZV A;  4P3H A;  1IEG A;  4V07 A;  4P2T A;  4V08 A;  1JQ6 A;  1ID4 A;  2WPO A;  1IED A;  1NJU A;  1IEF A;  1NKM A;  2PBK A;  1JQ7 A;  1NJT A;  1CMV A;  1O6E A;  1WPO A;  1AT3 A;  1IEC A;  4V0T A;  1LAY A;  3NJQ A;  1FL1 A;  3NJQ B; 
#chains in the Genus database with same CATH topology
 4CX8 A;  1NKK A;  1VZV A;  4P3H A;  1IEG A;  4V07 A;  4P2T A;  4V08 A;  1JQ6 A;  1ID4 A;  2WPO A;  1IED A;  1NJU A;  1IEF A;  1NKM A;  2PBK A;  1JQ7 A;  1NJT A;  1CMV A;  1O6E A;  1WPO A;  1AT3 A;  1IEC A;  4V0T A;  1LAY A;  3NJQ A;  1FL1 A;  3NJQ B; 
#chains in the Genus database with same CATH homology
 4CX8 A;  1NKK A;  1VZV A;  4P3H A;  1IEG A;  4V07 A;  4P2T A;  4V08 A;  1JQ6 A;  1ID4 A;  2WPO A;  1IED A;  1NJU A;  1IEF A;  1NKM A;  2PBK A;  1JQ7 A;  1NJT A;  1CMV A;  1O6E A;  1WPO A;  1AT3 A;  1IEC A;  4V0T A;  1LAY A;  3NJQ A;  1FL1 A;  3NJQ B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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