1IEGA

Crystal structure of the catalytic site mutant s134a/h157a of the human cytomegalovirus protease
Total Genus 64
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
248
structure length
207
Chain Sequence
QAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLALPLNINHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKVVEFLSGSYAGLSLAPFKAVALCSVGRRRGTLAVYGRDPEWVTQRFPDLTAADRDGLRAQWQGDPFRSDSYGLLGNSVDALYIRERLPKLRYDKQLVGVTERESYVKA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase
molecule keywords CAPSID PROTEIN P40: ASSEMBLIN PROTEASE
publication title Investigating the role of histidine 157 in the catalytic activity of human cytomegalovirus protease.
pubmed doi rcsb
source organism Human herpesvirus 5
total genus 64
structure length 207
sequence length 248
chains with identical sequence B
ec nomenclature ec 3.4.21.97: Assemblin.
pdb deposition date 2001-04-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.20.16.10 Alpha Beta Alpha-Beta Barrel Serine Protease, Human Cytomegalovirus Protease; Chain A Herpesvirus/Caudovirus protease domain 1iegA00
4V07A 1JQ6A 1O6EA 1NJUA 1IEDA 4V08A 4P2TA 4V0TA 1AT3A 1LAYA 1NJTA 4CX8A 1VZVA 1IEFA 1NKMA 3NJQA 1IECA 1FL1A 1JQ7A 1NKKA 2PBKA 4P3HA 3NJQB 1IEGA 2WPOA 1WPOA 1ID4A 1CMVA
chains in the Genus database with same CATH superfamily
4V07A 1JQ6A 1O6EA 1NJUA 1IEDA 4V08A 4P2TA 4V0TA 1AT3A 1LAYA 1NJTA 4CX8A 1VZVA 1IEFA 1NKMA 3NJQA 1IECA 1FL1A 1JQ7A 1NKKA 2PBKA 4P3HA 3NJQB 1IEGA 2WPOA 1WPOA 1ID4A 1CMVA
chains in the Genus database with same CATH topology
4V07A 1JQ6A 1O6EA 1NJUA 1IEDA 4V08A 4P2TA 4V0TA 1AT3A 1LAYA 1NJTA 4CX8A 1VZVA 1IEFA 1NKMA 3NJQA 1IECA 1FL1A 1JQ7A 1NKKA 2PBKA 4P3HA 3NJQB 1IEGA 2WPOA 1WPOA 1ID4A 1CMVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4V07 A;  1JQ6 A;  1O6E A;  1NJU A;  1IED A;  4V08 A;  4P2T A;  4V0T A;  1AT3 A;  1LAY A;  1NJT A;  4CX8 A;  1VZV A;  1IEF A;  1NKM A;  3NJQ A;  1IEC A;  1FL1 A;  1JQ7 A;  1NKK A;  2PBK A;  4P3H A;  3NJQ B;  1IEG A;  2WPO A;  1WPO A;  1ID4 A;  1CMV A; 
#chains in the Genus database with same CATH topology
 4V07 A;  1JQ6 A;  1O6E A;  1NJU A;  1IED A;  4V08 A;  4P2T A;  4V0T A;  1AT3 A;  1LAY A;  1NJT A;  4CX8 A;  1VZV A;  1IEF A;  1NKM A;  3NJQ A;  1IEC A;  1FL1 A;  1JQ7 A;  1NKK A;  2PBK A;  4P3H A;  3NJQ B;  1IEG A;  2WPO A;  1WPO A;  1ID4 A;  1CMV A; 
#chains in the Genus database with same CATH homology
 4V07 A;  1JQ6 A;  1O6E A;  1NJU A;  1IED A;  4V08 A;  4P2T A;  4V0T A;  1AT3 A;  1LAY A;  1NJT A;  4CX8 A;  1VZV A;  1IEF A;  1NKM A;  3NJQ A;  1IEC A;  1FL1 A;  1JQ7 A;  1NKK A;  2PBK A;  4P3H A;  3NJQ B;  1IEG A;  2WPO A;  1WPO A;  1ID4 A;  1CMV A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...