1XK9A

Pseudomanas exotoxin a in complex with the pj34 inhibitor
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
204
structure length
204
Chain Sequence
EFLGDGGDVSFSTRGTQNWTVERLLQAHRQLEERGYVFVGYHGTFLEAAQSIVFGGVRARSQDLDAIWRGFYIAGDPALAYGYAQDQEPDARGRIRNGALLRVYVPRSSLPGFYRTSLTLAAPEAAGEVERLIGHPLPLRLDAITGPEEEGGRLETILGWPLAERTVVIPSAIPTDPRNVGGDLDPSSIPDKEQAISALPDYAS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure-function analysis of water-soluble inhibitors of the catalytic domain of exotoxin A from Pseudomonas aeruginosa
pubmed doi rcsb
molecule keywords Exotoxin A
molecule tags Transferase
source organism Pseudomonas aeruginosa
total genus 50
structure length 204
sequence length 204
chains with identical sequence B
ec nomenclature ec 2.4.2.36: NAD(+)--diphthamide ADP-ribosyltransferase.
pdb deposition date 2004-09-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09009 Exotox-A_cataly Exotoxin A catalytic
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.175.10 Alpha Beta Alpha-Beta Complex Diphtheria Toxin; domain 1 Diphtheria Toxin, domain 1 1xk9A00
1F0LA 3ESSA 1ZM2B 2Q6MA 3B8HB 4AE0A 2ZITB 1ZM3B 3KI4A 1XDTT 3KI2A 1IKQA 1XK9A 1AERA 3Q9OA 3B82B 3KI5A 3NY6A 3KI3A 5I82A 1MDTA 3KI6A 1DDTA 1SGKA 2Q5TA 3KI7A 1ZM4B 3B78B 3KI0A 1IKPA 1DMAA 4OW6A 1ZM9B 4AE1A 1TOXA 3KI1A 1DTPA
chains in the Genus database with same CATH superfamily
1F0LA 3ESSA 1ZM2B 2Q6MA 3B8HB 4AE0A 2ZITB 1ZM3B 3KI4A 1XDTT 3KI2A 1IKQA 1XK9A 1AERA 3Q9OA 3B82B 3KI5A 3NY6A 3KI3A 5I82A 1MDTA 3KI6A 1DDTA 1SGKA 2Q5TA 3KI7A 1ZM4B 3B78B 3KI0A 1IKPA 1DMAA 4OW6A 1ZM9B 4AE1A 1TOXA 3KI1A 1DTPA
chains in the Genus database with same CATH topology
1F0LA 3ESSA 1ZM2B 2Q6MA 3B8HB 4AE0A 2ZITB 1ZM3B 3KI4A 1XDTT 3KI2A 1IKQA 1XK9A 1AERA 3Q9OA 3B82B 3KI5A 3NY6A 3KI3A 5I82A 1MDTA 3KI6A 1DDTA 1SGKA 2Q5TA 3KI7A 1ZM4B 3B78B 3KI0A 1IKPA 1DMAA 4OW6A 1ZM9B 4AE1A 1TOXA 3KI1A 1DTPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1F0L A;  3ESS A;  1ZM2 B;  2Q6M A;  3B8H B;  4AE0 A;  2ZIT B;  1ZM3 B;  3KI4 A;  1XDT T;  3KI2 A;  1IKQ A;  1XK9 A;  1AER A;  3Q9O A;  3B82 B;  3KI5 A;  3NY6 A;  3KI3 A;  5I82 A;  1MDT A;  3KI6 A;  1DDT A;  1SGK A;  2Q5T A;  3KI7 A;  1ZM4 B;  3B78 B;  3KI0 A;  1IKP A;  1DMA A;  4OW6 A;  1ZM9 B;  4AE1 A;  1TOX A;  3KI1 A;  1DTP A; 
#chains in the Genus database with same CATH topology
 1F0L A;  3ESS A;  1ZM2 B;  2Q6M A;  3B8H B;  4AE0 A;  2ZIT B;  1ZM3 B;  3KI4 A;  1XDT T;  3KI2 A;  1IKQ A;  1XK9 A;  1AER A;  3Q9O A;  3B82 B;  3KI5 A;  3NY6 A;  3KI3 A;  5I82 A;  1MDT A;  3KI6 A;  1DDT A;  1SGK A;  2Q5T A;  3KI7 A;  1ZM4 B;  3B78 B;  3KI0 A;  1IKP A;  1DMA A;  4OW6 A;  1ZM9 B;  4AE1 A;  1TOX A;  3KI1 A;  1DTP A; 
#chains in the Genus database with same CATH homology
 1F0L A;  3ESS A;  1ZM2 B;  2Q6M A;  3B8H B;  4AE0 A;  2ZIT B;  1ZM3 B;  3KI4 A;  1XDT T;  3KI2 A;  1IKQ A;  1XK9 A;  1AER A;  3Q9O A;  3B82 B;  3KI5 A;  3NY6 A;  3KI3 A;  5I82 A;  1MDT A;  3KI6 A;  1DDT A;  1SGK A;  2Q5T A;  3KI7 A;  1ZM4 B;  3B78 B;  3KI0 A;  1IKP A;  1DMA A;  4OW6 A;  1ZM9 B;  4AE1 A;  1TOX A;  3KI1 A;  1DTP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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