2DSQG

Structural basis for the inhibition of insulin-like growth factors by igf binding proteins
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
83
structure length
73
Chain Sequence
EPCRIELYRVVESLAKASKFYLPNCNKNGFYHSRQCETSMEAGLCWCVYPWNGKRIPGSPEIRGDPNCQIYFN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein binding/hormone/growth factor
molecule keywords Insulin-like growth factor-binding protein 4
publication title Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins.
pubmed doi rcsb
source organism Homo sapiens
total genus 12
structure length 73
sequence length 83
chains with identical sequence H
ec nomenclature
pdb deposition date 2006-07-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
G PF00086 Thyroglobulin_1 Thyroglobulin type-1 repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.800.10 Few Secondary Structures Irregular Invariant Chain; Chain I Thyroglobulin type-1 2dsqG00
2H7TA 1L3HA 2DSRG 1ICFI 2DSQG 1ZT3A 1ZT5A 1RMJA
chains in the Genus database with same CATH superfamily
2H7TA 1L3HA 2DSRG 1ICFI 2DSQG 1ZT3A 1ZT5A 1RMJA
chains in the Genus database with same CATH topology
2H7TA 1L3HA 2DSRG 1ICFI 2DSQG 1ZT3A 1ZT5A 1RMJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2H7T A;  1L3H A;  2DSR G;  1ICF I;  2DSQ G;  1ZT3 A;  1ZT5 A;  1RMJ A; 
#chains in the Genus database with same CATH topology
 2H7T A;  1L3H A;  2DSR G;  1ICF I;  2DSQ G;  1ZT3 A;  1ZT5 A;  1RMJ A; 
#chains in the Genus database with same CATH homology
 2H7T A;  1L3H A;  2DSR G;  1ICF I;  2DSQ G;  1ZT3 A;  1ZT5 A;  1RMJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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