2DSQG

Structural basis for the inhibition of insulin-like growth factors by igf binding proteins
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
83
structure length
73
Chain Sequence
EPCRIELYRVVESLAKASKFYLPNCNKNGFYHSRQCETSMEAGLCWCVYPWNGKRIPGSPEIRGDPNCQIYFN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins.
pubmed doi rcsb
molecule keywords Insulin-like growth factor-binding protein 4
molecule tags Protein binding/hormone/growth factor
source organism Homo sapiens
total genus 12
structure length 73
sequence length 83
chains with identical sequence H
ec nomenclature
pdb deposition date 2006-07-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
G PF00086 Thyroglobulin_1 Thyroglobulin type-1 repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.800.10 Few Secondary Structures Irregular Invariant Chain; Chain I Thyroglobulin type-1 2dsqG00
2DSQG 1ICFI 1RMJA 1L3HA 1ZT3A 1ZT5A 2DSRG 2H7TA
chains in the Genus database with same CATH superfamily
2DSQG 1ICFI 1RMJA 1L3HA 1ZT3A 1ZT5A 2DSRG 2H7TA
chains in the Genus database with same CATH topology
2DSQG 1ICFI 1RMJA 1L3HA 1ZT3A 1ZT5A 2DSRG 2H7TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DSQ G;  1ICF I;  1RMJ A;  1L3H A;  1ZT3 A;  1ZT5 A;  2DSR G;  2H7T A; 
#chains in the Genus database with same CATH topology
 2DSQ G;  1ICF I;  1RMJ A;  1L3H A;  1ZT3 A;  1ZT5 A;  2DSR G;  2H7T A; 
#chains in the Genus database with same CATH homology
 2DSQ G;  1ICF I;  1RMJ A;  1L3H A;  1ZT3 A;  1ZT5 A;  2DSR G;  2H7T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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