2H7TA

Solution structure of the c-terminal domain of insulin-like growth factor binding protein 2 (igfbp-2)
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
107
structure length
107
Chain Sequence
GPPPARTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECHLFYNEQQEARGVHTQRMQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure, dynamics and heparin binding of the C-terminal domain of insulin-like growth factor-binding protein-2 (IGFBP-2)
pubmed doi rcsb
molecule keywords Insulin-like growth factor-binding protein 2
molecule tags Protein binding
source organism Homo sapiens
total genus 12
structure length 107
sequence length 107
ec nomenclature
pdb deposition date 2006-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00086 Thyroglobulin_1 Thyroglobulin type-1 repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.800.10 Few Secondary Structures Irregular Invariant Chain; Chain I Thyroglobulin type-1 2h7tA01
1ICFI 2DSQG 2H7TA 1ZT3A 1RMJA 1ZT5A 2DSRG 1L3HA
chains in the Genus database with same CATH superfamily
1ICFI 2DSQG 2H7TA 1ZT3A 1RMJA 1ZT5A 2DSRG 1L3HA
chains in the Genus database with same CATH topology
1ICFI 2DSQG 2H7TA 1ZT3A 1RMJA 1ZT5A 2DSRG 1L3HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ICF I;  2DSQ G;  2H7T A;  1ZT3 A;  1RMJ A;  1ZT5 A;  2DSR G;  1L3H A; 
#chains in the Genus database with same CATH topology
 1ICF I;  2DSQ G;  2H7T A;  1ZT3 A;  1RMJ A;  1ZT5 A;  2DSR G;  1L3H A; 
#chains in the Genus database with same CATH homology
 1ICF I;  2DSQ G;  2H7T A;  1ZT3 A;  1RMJ A;  1ZT5 A;  2DSR G;  1L3H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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