2EIJA

Bovine heart cytochrome c oxidase in the fully reduced state
Total Genus 207
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
207
sequence length
513
structure length
513
Chain Sequence
FINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A histidine residue acting as a controlling site for dioxygen reduction and proton pumping by cytochrome c oxidase
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Cytochrome c oxidase subunit 1
total genus 207
structure length 513
sequence length 513
chains with identical sequence N
ec nomenclature ec 1.9.3.1: Cytochrome-c oxidase.
pdb deposition date 2007-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00115 COX1 Cytochrome C and Quinol oxidase polypeptide I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase; Chain A Cytochrome c oxidase-like, subunit I domain 2eijA00
3EH5A 3FYEA 1V54A 2OCCA 3WFBB 4FAAA 3S8GA 3QJRA 1V55A 3ASOA 4G7SA 3OMNA 3QJUA 4GP5A 2EILA 4GP4A 3WFEB 3EH4A 3ABKA 5B1BA 3X2QA 1M56A 3S3DA 3FYIA 3ABMA 3HB3A 2DYSA 3BVDA 4G7RA 3AG2A 3ABLA 3QJTA 3ASNA 3OMAA 4XYDA 3WFCB 2Y69A 2QPEA 3S3CA 4G7QA 1FFTA 2EIJA 3AYGA 2EINA 3S3BA 3EH3A 3OM3A 4G70A 4GP8A 2YEVA 3DTUA 2GSMA 5B3SA 4G72A 3AG3A 1AR1A 3AG4A 5DJQA 3S8FA 2EIMA 1M57A 1QLEA 2QPDA 3MK7A 1XMEA 4G71A 3AG1A 1OCRA 3WG7A 2EIKA 3QJQA 3EHBA 3QJVA 4N4YA 4FA7A 5B1AA 1EHKA 2DYRA 1OCCA 1OCZA 3O0RB 3OMIA 2ZXWA 3AYFA 5IY5A 3WFDB 1OCOA 3QJSA
chains in the Genus database with same CATH superfamily
3EH5A 3FYEA 1V54A 2OCCA 3WFBB 4FAAA 3S8GA 3QJRA 1V55A 3ASOA 4G7SA 3OMNA 3QJUA 4GP5A 2EILA 4GP4A 3WFEB 3EH4A 3ABKA 5B1BA 3X2QA 1M56A 3S3DA 3FYIA 3ABMA 3HB3A 2DYSA 3BVDA 4G7RA 3AG2A 3ABLA 3QJTA 3ASNA 3OMAA 4XYDA 3WFCB 2Y69A 2QPEA 3S3CA 4G7QA 1FFTA 2EIJA 3AYGA 2EINA 3S3BA 3EH3A 3OM3A 4G70A 4GP8A 2YEVA 3DTUA 2GSMA 5B3SA 4G72A 3AG3A 1AR1A 3AG4A 5DJQA 3S8FA 2EIMA 1M57A 1QLEA 2QPDA 3MK7A 1XMEA 4G71A 3AG1A 1OCRA 3WG7A 2EIKA 3QJQA 3EHBA 3QJVA 4N4YA 4FA7A 5B1AA 1EHKA 2DYRA 1OCCA 1OCZA 3O0RB 3OMIA 2ZXWA 3AYFA 5IY5A 3WFDB 1OCOA 3QJSA
chains in the Genus database with same CATH topology
3EH5A 3FYEA 1V54A 2OCCA 3WFBB 4FAAA 3S8GA 3QJRA 1V55A 3ASOA 4G7SA 3OMNA 3QJUA 4GP5A 2EILA 4GP4A 3WFEB 3EH4A 3ABKA 5B1BA 3X2QA 1M56A 3S3DA 3FYIA 3ABMA 3HB3A 2DYSA 3BVDA 4G7RA 3AG2A 3ABLA 3QJTA 3ASNA 3OMAA 4XYDA 3WFCB 2Y69A 2QPEA 3S3CA 4G7QA 1FFTA 2EIJA 3AYGA 2EINA 3S3BA 3EH3A 3OM3A 4G70A 4GP8A 2YEVA 3DTUA 2GSMA 5B3SA 4G72A 3AG3A 1AR1A 3AG4A 5DJQA 3S8FA 2EIMA 1M57A 1QLEA 2QPDA 3MK7A 1XMEA 4G71A 3AG1A 1OCRA 3WG7A 2EIKA 3QJQA 3EHBA 3QJVA 4N4YA 4FA7A 5B1AA 1EHKA 2DYRA 1OCCA 1OCZA 3O0RB 3OMIA 2ZXWA 3AYFA 5IY5A 3WFDB 1OCOA 3QJSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EH5 A;  3FYE A;  1V54 A;  2OCC A;  3WFB B;  4FAA A;  3S8G A;  3QJR A;  1V55 A;  3ASO A;  4G7S A;  3OMN A;  3QJU A;  4GP5 A;  2EIL A;  4GP4 A;  3WFE B;  3EH4 A;  3ABK A;  5B1B A;  3X2Q A;  1M56 A;  3S3D A;  3FYI A;  3ABM A;  3HB3 A;  2DYS A;  3BVD A;  4G7R A;  3AG2 A;  3ABL A;  3QJT A;  3ASN A;  3OMA A;  4XYD A;  3WFC B;  2Y69 A;  2QPE A;  3S3C A;  4G7Q A;  1FFT A;  2EIJ A;  3AYG A;  2EIN A;  3S3B A;  3EH3 A;  3OM3 A;  4G70 A;  4GP8 A;  2YEV A;  3DTU A;  2GSM A;  5B3S A;  4G72 A;  3AG3 A;  1AR1 A;  3AG4 A;  5DJQ A;  3S8F A;  2EIM A;  1M57 A;  1QLE A;  2QPD A;  3MK7 A;  1XME A;  4G71 A;  3AG1 A;  1OCR A;  3WG7 A;  2EIK A;  3QJQ A;  3EHB A;  3QJV A;  4N4Y A;  4FA7 A;  5B1A A;  1EHK A;  2DYR A;  1OCC A;  1OCZ A;  3O0R B;  3OMI A;  2ZXW A;  3AYF A;  5IY5 A;  3WFD B;  1OCO A;  3QJS A; 
#chains in the Genus database with same CATH topology
 3EH5 A;  3FYE A;  1V54 A;  2OCC A;  3WFB B;  4FAA A;  3S8G A;  3QJR A;  1V55 A;  3ASO A;  4G7S A;  3OMN A;  3QJU A;  4GP5 A;  2EIL A;  4GP4 A;  3WFE B;  3EH4 A;  3ABK A;  5B1B A;  3X2Q A;  1M56 A;  3S3D A;  3FYI A;  3ABM A;  3HB3 A;  2DYS A;  3BVD A;  4G7R A;  3AG2 A;  3ABL A;  3QJT A;  3ASN A;  3OMA A;  4XYD A;  3WFC B;  2Y69 A;  2QPE A;  3S3C A;  4G7Q A;  1FFT A;  2EIJ A;  3AYG A;  2EIN A;  3S3B A;  3EH3 A;  3OM3 A;  4G70 A;  4GP8 A;  2YEV A;  3DTU A;  2GSM A;  5B3S A;  4G72 A;  3AG3 A;  1AR1 A;  3AG4 A;  5DJQ A;  3S8F A;  2EIM A;  1M57 A;  1QLE A;  2QPD A;  3MK7 A;  1XME A;  4G71 A;  3AG1 A;  1OCR A;  3WG7 A;  2EIK A;  3QJQ A;  3EHB A;  3QJV A;  4N4Y A;  4FA7 A;  5B1A A;  1EHK A;  2DYR A;  1OCC A;  1OCZ A;  3O0R B;  3OMI A;  2ZXW A;  3AYF A;  5IY5 A;  3WFD B;  1OCO A;  3QJS A; 
#chains in the Genus database with same CATH homology
 3EH5 A;  3FYE A;  1V54 A;  2OCC A;  3WFB B;  4FAA A;  3S8G A;  3QJR A;  1V55 A;  3ASO A;  4G7S A;  3OMN A;  3QJU A;  4GP5 A;  2EIL A;  4GP4 A;  3WFE B;  3EH4 A;  3ABK A;  5B1B A;  3X2Q A;  1M56 A;  3S3D A;  3FYI A;  3ABM A;  3HB3 A;  2DYS A;  3BVD A;  4G7R A;  3AG2 A;  3ABL A;  3QJT A;  3ASN A;  3OMA A;  4XYD A;  3WFC B;  2Y69 A;  2QPE A;  3S3C A;  4G7Q A;  1FFT A;  2EIJ A;  3AYG A;  2EIN A;  3S3B A;  3EH3 A;  3OM3 A;  4G70 A;  4GP8 A;  2YEV A;  3DTU A;  2GSM A;  5B3S A;  4G72 A;  3AG3 A;  1AR1 A;  3AG4 A;  5DJQ A;  3S8F A;  2EIM A;  1M57 A;  1QLE A;  2QPD A;  3MK7 A;  1XME A;  4G71 A;  3AG1 A;  1OCR A;  3WG7 A;  2EIK A;  3QJQ A;  3EHB A;  3QJV A;  4N4Y A;  4FA7 A;  5B1A A;  1EHK A;  2DYR A;  1OCC A;  1OCZ A;  3O0R B;  3OMI A;  2ZXW A;  3AYF A;  5IY5 A;  3WFD B;  1OCO A;  3QJS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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