2EIKA

Cadmium ion binding structure of bovine heart cytochrome c oxidase in the fully reduced state
Total Genus 208
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
208
sequence length
513
structure length
513
Chain Sequence
FINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A histidine residue acting as a controlling site for dioxygen reduction and proton pumping by cytochrome c oxidase
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Cytochrome c oxidase subunit 1
total genus 208
structure length 513
sequence length 513
chains with identical sequence N
ec nomenclature ec 1.9.3.1: Cytochrome-c oxidase.
pdb deposition date 2007-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00115 COX1 Cytochrome C and Quinol oxidase polypeptide I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase; Chain A Cytochrome c oxidase-like, subunit I domain 2eikA00
3ABMA 3ABKA 4G7SA 1QLEA 5IY5A 1M57A 4G71A 3OMAA 3QJRA 3WFDB 3BVDA 3AG4A 3FYEA 2OCCA 3QJTA 1M56A 3WG7A 2Y69A 4G7QA 1FFTA 1XMEA 2EIKA 1OCRA 2EIMA 4FA7A 3EH5A 4G7RA 4XYDA 3WFEB 3S3BA 3FYIA 3DTUA 3OMIA 1AR1A 2EILA 2DYRA 3AG2A 2EIJA 3S3CA 2DYSA 3QJQA 1OCCA 3MK7A 3O0RB 2ZXWA 1V54A 4GP4A 3AYGA 4FAAA 3AG3A 2YEVA 5B1BA 3AG1A 3EHBA 1V55A 3S8GA 4GP5A 1OCZA 3WFCB 3ASOA 4GP8A 3QJUA 3OM3A 3X2QA 4N4YA 3HB3A 3WFBB 3OMNA 3AYFA 3QJSA 2QPEA 5B1AA 3ABLA 4G70A 2EINA 3EH4A 2QPDA 3S3DA 5DJQA 1OCOA 2GSMA 4G72A 3S8FA 5B3SA 3QJVA 1EHKA 3ASNA 3EH3A
chains in the Genus database with same CATH superfamily
3ABMA 3ABKA 4G7SA 1QLEA 5IY5A 1M57A 4G71A 3OMAA 3QJRA 3WFDB 3BVDA 3AG4A 3FYEA 2OCCA 3QJTA 1M56A 3WG7A 2Y69A 4G7QA 1FFTA 1XMEA 2EIKA 1OCRA 2EIMA 4FA7A 3EH5A 4G7RA 4XYDA 3WFEB 3S3BA 3FYIA 3DTUA 3OMIA 1AR1A 2EILA 2DYRA 3AG2A 2EIJA 3S3CA 2DYSA 3QJQA 1OCCA 3MK7A 3O0RB 2ZXWA 1V54A 4GP4A 3AYGA 4FAAA 3AG3A 2YEVA 5B1BA 3AG1A 3EHBA 1V55A 3S8GA 4GP5A 1OCZA 3WFCB 3ASOA 4GP8A 3QJUA 3OM3A 3X2QA 4N4YA 3HB3A 3WFBB 3OMNA 3AYFA 3QJSA 2QPEA 5B1AA 3ABLA 4G70A 2EINA 3EH4A 2QPDA 3S3DA 5DJQA 1OCOA 2GSMA 4G72A 3S8FA 5B3SA 3QJVA 1EHKA 3ASNA 3EH3A
chains in the Genus database with same CATH topology
3ABMA 3ABKA 4G7SA 1QLEA 5IY5A 1M57A 4G71A 3OMAA 3QJRA 3WFDB 3BVDA 3AG4A 3FYEA 2OCCA 3QJTA 1M56A 3WG7A 2Y69A 4G7QA 1FFTA 1XMEA 2EIKA 1OCRA 2EIMA 4FA7A 3EH5A 4G7RA 4XYDA 3WFEB 3S3BA 3FYIA 3DTUA 3OMIA 1AR1A 2EILA 2DYRA 3AG2A 2EIJA 3S3CA 2DYSA 3QJQA 1OCCA 3MK7A 3O0RB 2ZXWA 1V54A 4GP4A 3AYGA 4FAAA 3AG3A 2YEVA 5B1BA 3AG1A 3EHBA 1V55A 3S8GA 4GP5A 1OCZA 3WFCB 3ASOA 4GP8A 3QJUA 3OM3A 3X2QA 4N4YA 3HB3A 3WFBB 3OMNA 3AYFA 3QJSA 2QPEA 5B1AA 3ABLA 4G70A 2EINA 3EH4A 2QPDA 3S3DA 5DJQA 1OCOA 2GSMA 4G72A 3S8FA 5B3SA 3QJVA 1EHKA 3ASNA 3EH3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ABM A;  3ABK A;  4G7S A;  1QLE A;  5IY5 A;  1M57 A;  4G71 A;  3OMA A;  3QJR A;  3WFD B;  3BVD A;  3AG4 A;  3FYE A;  2OCC A;  3QJT A;  1M56 A;  3WG7 A;  2Y69 A;  4G7Q A;  1FFT A;  1XME A;  2EIK A;  1OCR A;  2EIM A;  4FA7 A;  3EH5 A;  4G7R A;  4XYD A;  3WFE B;  3S3B A;  3FYI A;  3DTU A;  3OMI A;  1AR1 A;  2EIL A;  2DYR A;  3AG2 A;  2EIJ A;  3S3C A;  2DYS A;  3QJQ A;  1OCC A;  3MK7 A;  3O0R B;  2ZXW A;  1V54 A;  4GP4 A;  3AYG A;  4FAA A;  3AG3 A;  2YEV A;  5B1B A;  3AG1 A;  3EHB A;  1V55 A;  3S8G A;  4GP5 A;  1OCZ A;  3WFC B;  3ASO A;  4GP8 A;  3QJU A;  3OM3 A;  3X2Q A;  4N4Y A;  3HB3 A;  3WFB B;  3OMN A;  3AYF A;  3QJS A;  2QPE A;  5B1A A;  3ABL A;  4G70 A;  2EIN A;  3EH4 A;  2QPD A;  3S3D A;  5DJQ A;  1OCO A;  2GSM A;  4G72 A;  3S8F A;  5B3S A;  3QJV A;  1EHK A;  3ASN A;  3EH3 A; 
#chains in the Genus database with same CATH topology
 3ABM A;  3ABK A;  4G7S A;  1QLE A;  5IY5 A;  1M57 A;  4G71 A;  3OMA A;  3QJR A;  3WFD B;  3BVD A;  3AG4 A;  3FYE A;  2OCC A;  3QJT A;  1M56 A;  3WG7 A;  2Y69 A;  4G7Q A;  1FFT A;  1XME A;  2EIK A;  1OCR A;  2EIM A;  4FA7 A;  3EH5 A;  4G7R A;  4XYD A;  3WFE B;  3S3B A;  3FYI A;  3DTU A;  3OMI A;  1AR1 A;  2EIL A;  2DYR A;  3AG2 A;  2EIJ A;  3S3C A;  2DYS A;  3QJQ A;  1OCC A;  3MK7 A;  3O0R B;  2ZXW A;  1V54 A;  4GP4 A;  3AYG A;  4FAA A;  3AG3 A;  2YEV A;  5B1B A;  3AG1 A;  3EHB A;  1V55 A;  3S8G A;  4GP5 A;  1OCZ A;  3WFC B;  3ASO A;  4GP8 A;  3QJU A;  3OM3 A;  3X2Q A;  4N4Y A;  3HB3 A;  3WFB B;  3OMN A;  3AYF A;  3QJS A;  2QPE A;  5B1A A;  3ABL A;  4G70 A;  2EIN A;  3EH4 A;  2QPD A;  3S3D A;  5DJQ A;  1OCO A;  2GSM A;  4G72 A;  3S8F A;  5B3S A;  3QJV A;  1EHK A;  3ASN A;  3EH3 A; 
#chains in the Genus database with same CATH homology
 3ABM A;  3ABK A;  4G7S A;  1QLE A;  5IY5 A;  1M57 A;  4G71 A;  3OMA A;  3QJR A;  3WFD B;  3BVD A;  3AG4 A;  3FYE A;  2OCC A;  3QJT A;  1M56 A;  3WG7 A;  2Y69 A;  4G7Q A;  1FFT A;  1XME A;  2EIK A;  1OCR A;  2EIM A;  4FA7 A;  3EH5 A;  4G7R A;  4XYD A;  3WFE B;  3S3B A;  3FYI A;  3DTU A;  3OMI A;  1AR1 A;  2EIL A;  2DYR A;  3AG2 A;  2EIJ A;  3S3C A;  2DYS A;  3QJQ A;  1OCC A;  3MK7 A;  3O0R B;  2ZXW A;  1V54 A;  4GP4 A;  3AYG A;  4FAA A;  3AG3 A;  2YEV A;  5B1B A;  3AG1 A;  3EHB A;  1V55 A;  3S8G A;  4GP5 A;  1OCZ A;  3WFC B;  3ASO A;  4GP8 A;  3QJU A;  3OM3 A;  3X2Q A;  4N4Y A;  3HB3 A;  3WFB B;  3OMN A;  3AYF A;  3QJS A;  2QPE A;  5B1A A;  3ABL A;  4G70 A;  2EIN A;  3EH4 A;  2QPD A;  3S3D A;  5DJQ A;  1OCO A;  2GSM A;  4G72 A;  3S8F A;  5B3S A;  3QJV A;  1EHK A;  3ASN A;  3EH3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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