2EINA

Zinc ion binding structure of bovine heart cytochrome c oxidase in the fully oxidized state
Total Genus 202
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
202
sequence length
513
structure length
513
Chain Sequence
FINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A histidine residue acting as a controlling site for dioxygen reduction and proton pumping by cytochrome c oxidase
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Cytochrome c oxidase subunit 1
total genus 202
structure length 513
sequence length 513
chains with identical sequence N
ec nomenclature ec 1.9.3.1: Cytochrome-c oxidase.
pdb deposition date 2007-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00115 COX1 Cytochrome C and Quinol oxidase polypeptide I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase; Chain A Cytochrome c oxidase-like, subunit I domain 2einA00
2EIJA 1AR1A 2EIKA 2EINA 3O0RB 3WFDB 3S3DA 4GP8A 3QJUA 3QJQA 4G70A 3QJTA 3BVDA 3EH4A 3EH5A 3AG2A 3ABKA 5B1AA 3ASNA 5DJQA 2OCCA 3QJSA 3DTUA 1QLEA 3S3CA 3FYEA 3OMIA 2YEVA 3ABLA 3WG7A 5B3SA 3HB3A 3S3BA 1V55A 4N4YA 4G7RA 3QJVA 4FAAA 3FYIA 4G71A 3EH3A 4G72A 3AG4A 3AYFA 4G7QA 2DYRA 3MK7A 1M57A 2QPEA 4GP4A 3AYGA 1FFTA 4G7SA 3OMAA 1OCRA 1OCCA 3QJRA 1M56A 3OM3A 3WFEB 3ABMA 2QPDA 3WFBB 1XMEA 3EHBA 2Y69A 3S8FA 2EILA 1EHKA 3X2QA 1V54A 3AG3A 4GP5A 5B1BA 2DYSA 3ASOA 4FA7A 1OCZA 1OCOA 2EIMA 5IY5A 2GSMA 4XYDA 2ZXWA 3WFCB 3AG1A 3S8GA 3OMNA
chains in the Genus database with same CATH superfamily
2EIJA 1AR1A 2EIKA 2EINA 3O0RB 3WFDB 3S3DA 4GP8A 3QJUA 3QJQA 4G70A 3QJTA 3BVDA 3EH4A 3EH5A 3AG2A 3ABKA 5B1AA 3ASNA 5DJQA 2OCCA 3QJSA 3DTUA 1QLEA 3S3CA 3FYEA 3OMIA 2YEVA 3ABLA 3WG7A 5B3SA 3HB3A 3S3BA 1V55A 4N4YA 4G7RA 3QJVA 4FAAA 3FYIA 4G71A 3EH3A 4G72A 3AG4A 3AYFA 4G7QA 2DYRA 3MK7A 1M57A 2QPEA 4GP4A 3AYGA 1FFTA 4G7SA 3OMAA 1OCRA 1OCCA 3QJRA 1M56A 3OM3A 3WFEB 3ABMA 2QPDA 3WFBB 1XMEA 3EHBA 2Y69A 3S8FA 2EILA 1EHKA 3X2QA 1V54A 3AG3A 4GP5A 5B1BA 2DYSA 3ASOA 4FA7A 1OCZA 1OCOA 2EIMA 5IY5A 2GSMA 4XYDA 2ZXWA 3WFCB 3AG1A 3S8GA 3OMNA
chains in the Genus database with same CATH topology
2EIJA 1AR1A 2EIKA 2EINA 3O0RB 3WFDB 3S3DA 4GP8A 3QJUA 3QJQA 4G70A 3QJTA 3BVDA 3EH4A 3EH5A 3AG2A 3ABKA 5B1AA 3ASNA 5DJQA 2OCCA 3QJSA 3DTUA 1QLEA 3S3CA 3FYEA 3OMIA 2YEVA 3ABLA 3WG7A 5B3SA 3HB3A 3S3BA 1V55A 4N4YA 4G7RA 3QJVA 4FAAA 3FYIA 4G71A 3EH3A 4G72A 3AG4A 3AYFA 4G7QA 2DYRA 3MK7A 1M57A 2QPEA 4GP4A 3AYGA 1FFTA 4G7SA 3OMAA 1OCRA 1OCCA 3QJRA 1M56A 3OM3A 3WFEB 3ABMA 2QPDA 3WFBB 1XMEA 3EHBA 2Y69A 3S8FA 2EILA 1EHKA 3X2QA 1V54A 3AG3A 4GP5A 5B1BA 2DYSA 3ASOA 4FA7A 1OCZA 1OCOA 2EIMA 5IY5A 2GSMA 4XYDA 2ZXWA 3WFCB 3AG1A 3S8GA 3OMNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EIJ A;  1AR1 A;  2EIK A;  2EIN A;  3O0R B;  3WFD B;  3S3D A;  4GP8 A;  3QJU A;  3QJQ A;  4G70 A;  3QJT A;  3BVD A;  3EH4 A;  3EH5 A;  3AG2 A;  3ABK A;  5B1A A;  3ASN A;  5DJQ A;  2OCC A;  3QJS A;  3DTU A;  1QLE A;  3S3C A;  3FYE A;  3OMI A;  2YEV A;  3ABL A;  3WG7 A;  5B3S A;  3HB3 A;  3S3B A;  1V55 A;  4N4Y A;  4G7R A;  3QJV A;  4FAA A;  3FYI A;  4G71 A;  3EH3 A;  4G72 A;  3AG4 A;  3AYF A;  4G7Q A;  2DYR A;  3MK7 A;  1M57 A;  2QPE A;  4GP4 A;  3AYG A;  1FFT A;  4G7S A;  3OMA A;  1OCR A;  1OCC A;  3QJR A;  1M56 A;  3OM3 A;  3WFE B;  3ABM A;  2QPD A;  3WFB B;  1XME A;  3EHB A;  2Y69 A;  3S8F A;  2EIL A;  1EHK A;  3X2Q A;  1V54 A;  3AG3 A;  4GP5 A;  5B1B A;  2DYS A;  3ASO A;  4FA7 A;  1OCZ A;  1OCO A;  2EIM A;  5IY5 A;  2GSM A;  4XYD A;  2ZXW A;  3WFC B;  3AG1 A;  3S8G A;  3OMN A; 
#chains in the Genus database with same CATH topology
 2EIJ A;  1AR1 A;  2EIK A;  2EIN A;  3O0R B;  3WFD B;  3S3D A;  4GP8 A;  3QJU A;  3QJQ A;  4G70 A;  3QJT A;  3BVD A;  3EH4 A;  3EH5 A;  3AG2 A;  3ABK A;  5B1A A;  3ASN A;  5DJQ A;  2OCC A;  3QJS A;  3DTU A;  1QLE A;  3S3C A;  3FYE A;  3OMI A;  2YEV A;  3ABL A;  3WG7 A;  5B3S A;  3HB3 A;  3S3B A;  1V55 A;  4N4Y A;  4G7R A;  3QJV A;  4FAA A;  3FYI A;  4G71 A;  3EH3 A;  4G72 A;  3AG4 A;  3AYF A;  4G7Q A;  2DYR A;  3MK7 A;  1M57 A;  2QPE A;  4GP4 A;  3AYG A;  1FFT A;  4G7S A;  3OMA A;  1OCR A;  1OCC A;  3QJR A;  1M56 A;  3OM3 A;  3WFE B;  3ABM A;  2QPD A;  3WFB B;  1XME A;  3EHB A;  2Y69 A;  3S8F A;  2EIL A;  1EHK A;  3X2Q A;  1V54 A;  3AG3 A;  4GP5 A;  5B1B A;  2DYS A;  3ASO A;  4FA7 A;  1OCZ A;  1OCO A;  2EIM A;  5IY5 A;  2GSM A;  4XYD A;  2ZXW A;  3WFC B;  3AG1 A;  3S8G A;  3OMN A; 
#chains in the Genus database with same CATH homology
 2EIJ A;  1AR1 A;  2EIK A;  2EIN A;  3O0R B;  3WFD B;  3S3D A;  4GP8 A;  3QJU A;  3QJQ A;  4G70 A;  3QJT A;  3BVD A;  3EH4 A;  3EH5 A;  3AG2 A;  3ABK A;  5B1A A;  3ASN A;  5DJQ A;  2OCC A;  3QJS A;  3DTU A;  1QLE A;  3S3C A;  3FYE A;  3OMI A;  2YEV A;  3ABL A;  3WG7 A;  5B3S A;  3HB3 A;  3S3B A;  1V55 A;  4N4Y A;  4G7R A;  3QJV A;  4FAA A;  3FYI A;  4G71 A;  3EH3 A;  4G72 A;  3AG4 A;  3AYF A;  4G7Q A;  2DYR A;  3MK7 A;  1M57 A;  2QPE A;  4GP4 A;  3AYG A;  1FFT A;  4G7S A;  3OMA A;  1OCR A;  1OCC A;  3QJR A;  1M56 A;  3OM3 A;  3WFE B;  3ABM A;  2QPD A;  3WFB B;  1XME A;  3EHB A;  2Y69 A;  3S8F A;  2EIL A;  1EHK A;  3X2Q A;  1V54 A;  3AG3 A;  4GP5 A;  5B1B A;  2DYS A;  3ASO A;  4FA7 A;  1OCZ A;  1OCO A;  2EIM A;  5IY5 A;  2GSM A;  4XYD A;  2ZXW A;  3WFC B;  3AG1 A;  3S8G A;  3OMN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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