2EINA

Zinc ion binding structure of bovine heart cytochrome c oxidase in the fully oxidized state
Total Genus 202
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
202
sequence length
513
structure length
513
Chain Sequence
FINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A histidine residue acting as a controlling site for dioxygen reduction and proton pumping by cytochrome c oxidase
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Cytochrome c oxidase subunit 1
total genus 202
structure length 513
sequence length 513
chains with identical sequence N
ec nomenclature ec 1.9.3.1: Cytochrome-c oxidase.
pdb deposition date 2007-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00115 COX1 Cytochrome C and Quinol oxidase polypeptide I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase; Chain A Cytochrome c oxidase-like, subunit I domain 2einA00
3S3BA 3ASNA 5IY5A 1FFTA 1OCCA 2DYRA 3ABMA 3ASOA 3X2QA 3WFBB 2ZXWA 2GSMA 4N4YA 2QPDA 2DYSA 3ABKA 3QJVA 3AG1A 4G7RA 3QJTA 1AR1A 3DTUA 3HB3A 3S3CA 3EH3A 1M56A 3WFCB 5DJQA 2OCCA 3EH5A 4G7SA 3WFEB 3O0RB 4GP4A 3S8FA 3S3DA 3OMIA 1QLEA 2Y69A 3AYGA 1OCRA 1EHKA 2EIKA 3WFDB 3FYEA 2YEVA 3QJQA 1OCZA 3AYFA 2EIMA 1V55A 4G71A 3EH4A 4G7QA 2EILA 1M57A 1XMEA 4GP8A 1OCOA 4FA7A 3AG2A 3QJRA 3WG7A 4GP5A 5B3SA 2EINA 3EHBA 3OM3A 3QJSA 4FAAA 3AG4A 3S8GA 3AG3A 4G70A 5B1BA 4XYDA 4G72A 3ABLA 3OMNA 3MK7A 3OMAA 2QPEA 3BVDA 2EIJA 3QJUA 1V54A 5B1AA 3FYIA
chains in the Genus database with same CATH superfamily
3S3BA 3ASNA 5IY5A 1FFTA 1OCCA 2DYRA 3ABMA 3ASOA 3X2QA 3WFBB 2ZXWA 2GSMA 4N4YA 2QPDA 2DYSA 3ABKA 3QJVA 3AG1A 4G7RA 3QJTA 1AR1A 3DTUA 3HB3A 3S3CA 3EH3A 1M56A 3WFCB 5DJQA 2OCCA 3EH5A 4G7SA 3WFEB 3O0RB 4GP4A 3S8FA 3S3DA 3OMIA 1QLEA 2Y69A 3AYGA 1OCRA 1EHKA 2EIKA 3WFDB 3FYEA 2YEVA 3QJQA 1OCZA 3AYFA 2EIMA 1V55A 4G71A 3EH4A 4G7QA 2EILA 1M57A 1XMEA 4GP8A 1OCOA 4FA7A 3AG2A 3QJRA 3WG7A 4GP5A 5B3SA 2EINA 3EHBA 3OM3A 3QJSA 4FAAA 3AG4A 3S8GA 3AG3A 4G70A 5B1BA 4XYDA 4G72A 3ABLA 3OMNA 3MK7A 3OMAA 2QPEA 3BVDA 2EIJA 3QJUA 1V54A 5B1AA 3FYIA
chains in the Genus database with same CATH topology
3S3BA 3ASNA 5IY5A 1FFTA 1OCCA 2DYRA 3ABMA 3ASOA 3X2QA 3WFBB 2ZXWA 2GSMA 4N4YA 2QPDA 2DYSA 3ABKA 3QJVA 3AG1A 4G7RA 3QJTA 1AR1A 3DTUA 3HB3A 3S3CA 3EH3A 1M56A 3WFCB 5DJQA 2OCCA 3EH5A 4G7SA 3WFEB 3O0RB 4GP4A 3S8FA 3S3DA 3OMIA 1QLEA 2Y69A 3AYGA 1OCRA 1EHKA 2EIKA 3WFDB 3FYEA 2YEVA 3QJQA 1OCZA 3AYFA 2EIMA 1V55A 4G71A 3EH4A 4G7QA 2EILA 1M57A 1XMEA 4GP8A 1OCOA 4FA7A 3AG2A 3QJRA 3WG7A 4GP5A 5B3SA 2EINA 3EHBA 3OM3A 3QJSA 4FAAA 3AG4A 3S8GA 3AG3A 4G70A 5B1BA 4XYDA 4G72A 3ABLA 3OMNA 3MK7A 3OMAA 2QPEA 3BVDA 2EIJA 3QJUA 1V54A 5B1AA 3FYIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S3B A;  3ASN A;  5IY5 A;  1FFT A;  1OCC A;  2DYR A;  3ABM A;  3ASO A;  3X2Q A;  3WFB B;  2ZXW A;  2GSM A;  4N4Y A;  2QPD A;  2DYS A;  3ABK A;  3QJV A;  3AG1 A;  4G7R A;  3QJT A;  1AR1 A;  3DTU A;  3HB3 A;  3S3C A;  3EH3 A;  1M56 A;  3WFC B;  5DJQ A;  2OCC A;  3EH5 A;  4G7S A;  3WFE B;  3O0R B;  4GP4 A;  3S8F A;  3S3D A;  3OMI A;  1QLE A;  2Y69 A;  3AYG A;  1OCR A;  1EHK A;  2EIK A;  3WFD B;  3FYE A;  2YEV A;  3QJQ A;  1OCZ A;  3AYF A;  2EIM A;  1V55 A;  4G71 A;  3EH4 A;  4G7Q A;  2EIL A;  1M57 A;  1XME A;  4GP8 A;  1OCO A;  4FA7 A;  3AG2 A;  3QJR A;  3WG7 A;  4GP5 A;  5B3S A;  2EIN A;  3EHB A;  3OM3 A;  3QJS A;  4FAA A;  3AG4 A;  3S8G A;  3AG3 A;  4G70 A;  5B1B A;  4XYD A;  4G72 A;  3ABL A;  3OMN A;  3MK7 A;  3OMA A;  2QPE A;  3BVD A;  2EIJ A;  3QJU A;  1V54 A;  5B1A A;  3FYI A; 
#chains in the Genus database with same CATH topology
 3S3B A;  3ASN A;  5IY5 A;  1FFT A;  1OCC A;  2DYR A;  3ABM A;  3ASO A;  3X2Q A;  3WFB B;  2ZXW A;  2GSM A;  4N4Y A;  2QPD A;  2DYS A;  3ABK A;  3QJV A;  3AG1 A;  4G7R A;  3QJT A;  1AR1 A;  3DTU A;  3HB3 A;  3S3C A;  3EH3 A;  1M56 A;  3WFC B;  5DJQ A;  2OCC A;  3EH5 A;  4G7S A;  3WFE B;  3O0R B;  4GP4 A;  3S8F A;  3S3D A;  3OMI A;  1QLE A;  2Y69 A;  3AYG A;  1OCR A;  1EHK A;  2EIK A;  3WFD B;  3FYE A;  2YEV A;  3QJQ A;  1OCZ A;  3AYF A;  2EIM A;  1V55 A;  4G71 A;  3EH4 A;  4G7Q A;  2EIL A;  1M57 A;  1XME A;  4GP8 A;  1OCO A;  4FA7 A;  3AG2 A;  3QJR A;  3WG7 A;  4GP5 A;  5B3S A;  2EIN A;  3EHB A;  3OM3 A;  3QJS A;  4FAA A;  3AG4 A;  3S8G A;  3AG3 A;  4G70 A;  5B1B A;  4XYD A;  4G72 A;  3ABL A;  3OMN A;  3MK7 A;  3OMA A;  2QPE A;  3BVD A;  2EIJ A;  3QJU A;  1V54 A;  5B1A A;  3FYI A; 
#chains in the Genus database with same CATH homology
 3S3B A;  3ASN A;  5IY5 A;  1FFT A;  1OCC A;  2DYR A;  3ABM A;  3ASO A;  3X2Q A;  3WFB B;  2ZXW A;  2GSM A;  4N4Y A;  2QPD A;  2DYS A;  3ABK A;  3QJV A;  3AG1 A;  4G7R A;  3QJT A;  1AR1 A;  3DTU A;  3HB3 A;  3S3C A;  3EH3 A;  1M56 A;  3WFC B;  5DJQ A;  2OCC A;  3EH5 A;  4G7S A;  3WFE B;  3O0R B;  4GP4 A;  3S8F A;  3S3D A;  3OMI A;  1QLE A;  2Y69 A;  3AYG A;  1OCR A;  1EHK A;  2EIK A;  3WFD B;  3FYE A;  2YEV A;  3QJQ A;  1OCZ A;  3AYF A;  2EIM A;  1V55 A;  4G71 A;  3EH4 A;  4G7Q A;  2EIL A;  1M57 A;  1XME A;  4GP8 A;  1OCO A;  4FA7 A;  3AG2 A;  3QJR A;  3WG7 A;  4GP5 A;  5B3S A;  2EIN A;  3EHB A;  3OM3 A;  3QJS A;  4FAA A;  3AG4 A;  3S8G A;  3AG3 A;  4G70 A;  5B1B A;  4XYD A;  4G72 A;  3ABL A;  3OMN A;  3MK7 A;  3OMA A;  2QPE A;  3BVD A;  2EIJ A;  3QJU A;  1V54 A;  5B1A A;  3FYI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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