2Q6MA

Catalytic fragment of cholix toxin from vibrio cholerae in complex with the pj34 inhibitor
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
206
structure length
201
Chain Sequence
GSHMAVITPQGVTNWTYQELEATHQALTREGYVFVGYHGTNHVAAQTIVNRIAPVTENEEKWGGLYVATHAEVAHGYARIKEGTGEYGLPTRAERDARGVMLRVYIPRASLERFYRTNTPLENAEEHITQVIGHSLPLRNEAFTGPESAGGEDETVIGWDMAIHAVAIPSTIPGNAYEELAIDEEAVAKEQSISTKPPYKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Cholix Toxin, a Novel ADP-ribosylating Factor from Vibrio cholerae.
pubmed doi rcsb
molecule keywords Cholix toxin
molecule tags Toxin
source organism Vibrio cholerae
total genus 56
structure length 201
sequence length 206
ec nomenclature ec 2.4.2.36: NAD(+)--diphthamide ADP-ribosyltransferase.
pdb deposition date 2007-06-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09009 Exotox-A_cataly Exotoxin A catalytic
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.175.10 Alpha Beta Alpha-Beta Complex Diphtheria Toxin; domain 1 Diphtheria Toxin, domain 1 2q6mA00
3KI7A 3KI4A 3KI0A 3B78B 4AE0A 4OW6A 3B82B 1XK9A 1ZM4B 3KI1A 1TOXA 1ZM9B 4AE1A 1AERA 2ZITB 2Q5TA 1MDTA 1F0LA 3KI3A 2Q6MA 3KI5A 1XDTT 1IKQA 1ZM2B 3B8HB 1ZM3B 1DMAA 5I82A 1SGKA 1DTPA 1DDTA 3NY6A 1IKPA 3KI6A 3Q9OA 3ESSA 3KI2A
chains in the Genus database with same CATH superfamily
3KI7A 3KI4A 3KI0A 3B78B 4AE0A 4OW6A 3B82B 1XK9A 1ZM4B 3KI1A 1TOXA 1ZM9B 4AE1A 1AERA 2ZITB 2Q5TA 1MDTA 1F0LA 3KI3A 2Q6MA 3KI5A 1XDTT 1IKQA 1ZM2B 3B8HB 1ZM3B 1DMAA 5I82A 1SGKA 1DTPA 1DDTA 3NY6A 1IKPA 3KI6A 3Q9OA 3ESSA 3KI2A
chains in the Genus database with same CATH topology
3KI7A 3KI4A 3KI0A 3B78B 4AE0A 4OW6A 3B82B 1XK9A 1ZM4B 3KI1A 1TOXA 1ZM9B 4AE1A 1AERA 2ZITB 2Q5TA 1MDTA 1F0LA 3KI3A 2Q6MA 3KI5A 1XDTT 1IKQA 1ZM2B 3B8HB 1ZM3B 1DMAA 5I82A 1SGKA 1DTPA 1DDTA 3NY6A 1IKPA 3KI6A 3Q9OA 3ESSA 3KI2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KI7 A;  3KI4 A;  3KI0 A;  3B78 B;  4AE0 A;  4OW6 A;  3B82 B;  1XK9 A;  1ZM4 B;  3KI1 A;  1TOX A;  1ZM9 B;  4AE1 A;  1AER A;  2ZIT B;  2Q5T A;  1MDT A;  1F0L A;  3KI3 A;  2Q6M A;  3KI5 A;  1XDT T;  1IKQ A;  1ZM2 B;  3B8H B;  1ZM3 B;  1DMA A;  5I82 A;  1SGK A;  1DTP A;  1DDT A;  3NY6 A;  1IKP A;  3KI6 A;  3Q9O A;  3ESS A;  3KI2 A; 
#chains in the Genus database with same CATH topology
 3KI7 A;  3KI4 A;  3KI0 A;  3B78 B;  4AE0 A;  4OW6 A;  3B82 B;  1XK9 A;  1ZM4 B;  3KI1 A;  1TOX A;  1ZM9 B;  4AE1 A;  1AER A;  2ZIT B;  2Q5T A;  1MDT A;  1F0L A;  3KI3 A;  2Q6M A;  3KI5 A;  1XDT T;  1IKQ A;  1ZM2 B;  3B8H B;  1ZM3 B;  1DMA A;  5I82 A;  1SGK A;  1DTP A;  1DDT A;  3NY6 A;  1IKP A;  3KI6 A;  3Q9O A;  3ESS A;  3KI2 A; 
#chains in the Genus database with same CATH homology
 3KI7 A;  3KI4 A;  3KI0 A;  3B78 B;  4AE0 A;  4OW6 A;  3B82 B;  1XK9 A;  1ZM4 B;  3KI1 A;  1TOX A;  1ZM9 B;  4AE1 A;  1AER A;  2ZIT B;  2Q5T A;  1MDT A;  1F0L A;  3KI3 A;  2Q6M A;  3KI5 A;  1XDT T;  1IKQ A;  1ZM2 B;  3B8H B;  1ZM3 B;  1DMA A;  5I82 A;  1SGK A;  1DTP A;  1DDT A;  3NY6 A;  1IKP A;  3KI6 A;  3Q9O A;  3ESS A;  3KI2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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