2QYFA

Crystal structure of the mad2/p31(comet)/mad2-binding peptide ternary complex
Total Genus 59
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
197
structure length
197
Chain Sequence
QGITARGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLELIKYLNNVVEQLKDWLYKCSVQKLVVVISNIESGEVLERWQFDIECDKTAKDDSAPREKSQKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVVPEKWEESGPQFITNSEEVRLRSFTTTIHKVNSMVAYKIPVND
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title p31comet blocks Mad2 activation through structural mimicry.
pubmed doi rcsb
molecule keywords Mitotic spindle assembly checkpoint protein MAD2A
molecule tags Cell cycle
source organism Homo sapiens
total genus 59
structure length 197
sequence length 197
chains with identical sequence C
ec nomenclature
pdb deposition date 2007-08-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02301 HORMA HORMA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.900.10 Alpha Beta 2-Layer Sandwich Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A HORMA domain 2qyfA00
4GK0A 4TZQA 1GO4A 4YK8B 1S2HA 4AEZB 5LCWZ 2QYFA 4TRKA 4TZLA 1DUJA 2V64A 3ABEC 1KLQA 4TZSA 4GK5A 4FJOC 4TZMA 4TZNA 3ABDA 4EXTC 5C50B 4J2GA 4TZJA 3GMHA 2V64D 3VU7C 2VFXA 4TZOA
chains in the Genus database with same CATH superfamily
4GK0A 4TZQA 1GO4A 4YK8B 1S2HA 2QYFB 4AEZB 5LCWZ 2QYFA 4TRKA 4TZLA 1DUJA 2V64A 3ABEC 1KLQA 4TZSA 4GK5A 4FJOC 4TZMA 4TZNA 3ABDA 4EXTC 5C50B 4J2GA 4TZJA 3GMHA 2V64D 3VU7C 2VFXA 4TZOA
chains in the Genus database with same CATH topology
4GK0A 4TZQA 1GO4A 4YK8B 1S2HA 4AEZB 5LCWZ 2QYFA 4TRKA 4TZLA 1DUJA 2V64A 3ABEC 1KLQA 4TZSA 4GK5A 4FJOC 4TZMA 4TZNA 3ABDA 4EXTC 5C50B 4J2GA 4TZJA 3GMHA 2V64D 3VU7C 2VFXA 4TZOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GK0 A;  4TZQ A;  1GO4 A;  4YK8 B;  1S2H A;  4AEZ B;  5LCW Z;  2QYF A;  4TRK A;  4TZL A;  1DUJ A;  2V64 A;  3ABE C;  1KLQ A;  4TZS A;  4GK5 A;  4FJO C;  4TZM A;  4TZN A;  3ABD A;  4EXT C;  5C50 B;  4J2G A;  4TZJ A;  3GMH A;  2V64 D;  3VU7 C;  2VFX A;  4TZO A; 
#chains in the Genus database with same CATH topology
 4GK0 A;  4TZQ A;  1GO4 A;  4YK8 B;  1S2H A;  2QYF B;  4AEZ B;  5LCW Z;  2QYF A;  4TRK A;  4TZL A;  1DUJ A;  2V64 A;  3ABE C;  1KLQ A;  4TZS A;  4GK5 A;  4FJO C;  4TZM A;  4TZN A;  3ABD A;  4EXT C;  5C50 B;  4J2G A;  4TZJ A;  3GMH A;  2V64 D;  3VU7 C;  2VFX A;  4TZO A; 
#chains in the Genus database with same CATH homology
 4GK0 A;  4TZQ A;  1GO4 A;  4YK8 B;  1S2H A;  4AEZ B;  5LCW Z;  2QYF A;  4TRK A;  4TZL A;  1DUJ A;  2V64 A;  3ABE C;  1KLQ A;  4TZS A;  4GK5 A;  4FJO C;  4TZM A;  4TZN A;  3ABD A;  4EXT C;  5C50 B;  4J2G A;  4TZJ A;  3GMH A;  2V64 D;  3VU7 C;  2VFX A;  4TZO A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...