2QYFA

Crystal structure of the mad2/p31(comet)/mad2-binding peptide ternary complex
Total Genus 59
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
197
structure length
197
Chain Sequence
QGITARGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLELIKYLNNVVEQLKDWLYKCSVQKLVVVISNIESGEVLERWQFDIECDKTAKDDSAPREKSQKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVVPEKWEESGPQFITNSEEVRLRSFTTTIHKVNSMVAYKIPVND
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title p31comet blocks Mad2 activation through structural mimicry.
pubmed doi rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords Mitotic spindle assembly checkpoint protein MAD2A
total genus 59
structure length 197
sequence length 197
chains with identical sequence C
ec nomenclature
pdb deposition date 2007-08-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02301 HORMA HORMA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.900.10 Alpha Beta 2-Layer Sandwich Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A HORMA domain 2qyfA00
1GO4A 2VFXA 4FJOC 3VU7C 5LCWZ 4J2GA 4TZMA 3ABDA 3ABEC 2QYFA 4AEZB 4TRKA 1S2HA 4TZQA 4EXTC 1DUJA 4TZOA 4GK5A 4TZJA 4TZNA 3GMHA 5C50B 2V64D 4GK0A 1KLQA 2V64A 4TZSA 4YK8B 4TZLA
chains in the Genus database with same CATH superfamily
1GO4A 2VFXA 4FJOC 3VU7C 5LCWZ 4J2GA 4TZMA 3ABDA 3ABEC 2QYFA 4AEZB 4TRKA 1S2HA 4TZQA 4EXTC 1DUJA 4TZOA 2QYFB 4GK5A 4TZJA 4TZNA 3GMHA 5C50B 2V64D 4GK0A 1KLQA 2V64A 4TZSA 4YK8B 4TZLA
chains in the Genus database with same CATH topology
1GO4A 2VFXA 4FJOC 3VU7C 5LCWZ 4J2GA 4TZMA 3ABDA 3ABEC 2QYFA 4AEZB 4TRKA 1S2HA 4TZQA 4EXTC 1DUJA 4TZOA 4GK5A 4TZJA 4TZNA 3GMHA 5C50B 2V64D 4GK0A 1KLQA 2V64A 4TZSA 4YK8B 4TZLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GO4 A;  2VFX A;  4FJO C;  3VU7 C;  5LCW Z;  4J2G A;  4TZM A;  3ABD A;  3ABE C;  2QYF A;  4AEZ B;  4TRK A;  1S2H A;  4TZQ A;  4EXT C;  1DUJ A;  4TZO A;  4GK5 A;  4TZJ A;  4TZN A;  3GMH A;  5C50 B;  2V64 D;  4GK0 A;  1KLQ A;  2V64 A;  4TZS A;  4YK8 B;  4TZL A; 
#chains in the Genus database with same CATH topology
 1GO4 A;  2VFX A;  4FJO C;  3VU7 C;  5LCW Z;  4J2G A;  4TZM A;  3ABD A;  3ABE C;  2QYF A;  4AEZ B;  4TRK A;  1S2H A;  4TZQ A;  4EXT C;  1DUJ A;  4TZO A;  2QYF B;  4GK5 A;  4TZJ A;  4TZN A;  3GMH A;  5C50 B;  2V64 D;  4GK0 A;  1KLQ A;  2V64 A;  4TZS A;  4YK8 B;  4TZL A; 
#chains in the Genus database with same CATH homology
 1GO4 A;  2VFX A;  4FJO C;  3VU7 C;  5LCW Z;  4J2G A;  4TZM A;  3ABD A;  3ABE C;  2QYF A;  4AEZ B;  4TRK A;  1S2H A;  4TZQ A;  4EXT C;  1DUJ A;  4TZO A;  4GK5 A;  4TZJ A;  4TZN A;  3GMH A;  5C50 B;  2V64 D;  4GK0 A;  1KLQ A;  2V64 A;  4TZS A;  4YK8 B;  4TZL A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...