2QYFA

Crystal structure of the mad2/p31(comet)/mad2-binding peptide ternary complex
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
197
structure length
197
Chain Sequence
QGITARGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLELIKYLNNVVEQLKDWLYKCSVQKLVVVISNIESGEVLERWQFDIECDKTAKDDSAPREKSQKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVVPEKWEESGPQFITNSEEVRLRSFTTTIHKVNSMVAYKIPVND
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell cycle
molecule keywords Mitotic spindle assembly checkpoint protein MAD2A
publication title p31comet blocks Mad2 activation through structural mimicry.
pubmed doi rcsb
source organism Homo sapiens
total genus 59
structure length 197
sequence length 197
chains with identical sequence C
ec nomenclature
pdb deposition date 2007-08-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02301 HORMA HORMA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.900.10 Alpha Beta 2-Layer Sandwich Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A HORMA domain 2qyfA00
2V64D 4GK5A 4AEZB 4TZOA 2QYFA 4TZQA 2VFXA 3ABDA 4TZJA 2V64A 4GK0A 4J2GA 4TZSA 4EXTC 1S2HA 3VU7C 4TZNA 5C50B 1KLQA 4TZMA 4FJOC 5LCWZ 1GO4A 4TZLA 4YK8B 3ABEC 1DUJA 4TRKA 3GMHA
chains in the Genus database with same CATH superfamily
2V64D 4GK5A 4AEZB 4TZOA 2QYFA 4TZQA 2VFXA 3ABDA 4TZJA 2V64A 4GK0A 4J2GA 4TZSA 4EXTC 1S2HA 3VU7C 4TZNA 5C50B 1KLQA 4TZMA 4FJOC 5LCWZ 1GO4A 2QYFB 4TZLA 4YK8B 3ABEC 1DUJA 4TRKA 3GMHA
chains in the Genus database with same CATH topology
2V64D 4GK5A 4AEZB 4TZOA 2QYFA 4TZQA 2VFXA 3ABDA 4TZJA 2V64A 4GK0A 4J2GA 4TZSA 4EXTC 1S2HA 3VU7C 4TZNA 5C50B 1KLQA 4TZMA 4FJOC 5LCWZ 1GO4A 4TZLA 4YK8B 3ABEC 1DUJA 4TRKA 3GMHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V64 D;  4GK5 A;  4AEZ B;  4TZO A;  2QYF A;  4TZQ A;  2VFX A;  3ABD A;  4TZJ A;  2V64 A;  4GK0 A;  4J2G A;  4TZS A;  4EXT C;  1S2H A;  3VU7 C;  4TZN A;  5C50 B;  1KLQ A;  4TZM A;  4FJO C;  5LCW Z;  1GO4 A;  4TZL A;  4YK8 B;  3ABE C;  1DUJ A;  4TRK A;  3GMH A; 
#chains in the Genus database with same CATH topology
 2V64 D;  4GK5 A;  4AEZ B;  4TZO A;  2QYF A;  4TZQ A;  2VFX A;  3ABD A;  4TZJ A;  2V64 A;  4GK0 A;  4J2G A;  4TZS A;  4EXT C;  1S2H A;  3VU7 C;  4TZN A;  5C50 B;  1KLQ A;  4TZM A;  4FJO C;  5LCW Z;  1GO4 A;  2QYF B;  4TZL A;  4YK8 B;  3ABE C;  1DUJ A;  4TRK A;  3GMH A; 
#chains in the Genus database with same CATH homology
 2V64 D;  4GK5 A;  4AEZ B;  4TZO A;  2QYF A;  4TZQ A;  2VFX A;  3ABD A;  4TZJ A;  2V64 A;  4GK0 A;  4J2G A;  4TZS A;  4EXT C;  1S2H A;  3VU7 C;  4TZN A;  5C50 B;  1KLQ A;  4TZM A;  4FJO C;  5LCW Z;  1GO4 A;  4TZL A;  4YK8 B;  3ABE C;  1DUJ A;  4TRK A;  3GMH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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