2QYFB

Crystal structure of the mad2/p31(comet)/mad2-binding peptide ternary complex
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
219
structure length
188
Chain Sequence
CMVPVVFPGPVQEGCCQFTCELLKHIMYQRQQLPLPYEQLKHCQQALAELESVLSHLEDFFARTLVPRVLILLGGNALSPKEFYELDLSLLAPDQSLSTAACLRRLFRAIFMADAFSELQAPPLMGTVVMAQGHRNCGEDWFRPKLNYRVPSRGHKLTVTLSCGRPSIRTTAWEDYIWFQAPVTFKGF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title p31comet blocks Mad2 activation through structural mimicry.
pubmed doi rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords Mitotic spindle assembly checkpoint protein MAD2A
total genus 43
structure length 188
sequence length 219
chains with identical sequence D
ec nomenclature
pdb deposition date 2007-08-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.900.20 Alpha Beta 2-Layer Sandwich Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A 2qyfB00
2QYFB
chains in the Genus database with same CATH superfamily
2QYFB 4TZQA 1GO4A 2V64A 4TZJA 4AEZB 3GMHA 3ABDA 1DUJA 4TZNA 4EXTC 4GK0A 4TZMA 4J2GA 5LCWZ 2QYFA 2V64D 4YK8B 4FJOC 1KLQA 4TZLA 3VU7C 4TRKA 1S2HA 4TZOA 2VFXA 4GK5A 4TZSA 5C50B 3ABEC
chains in the Genus database with same CATH topology
2QYFB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QYF B; 
#chains in the Genus database with same CATH topology
 2QYF B;  4TZQ A;  1GO4 A;  2V64 A;  4TZJ A;  4AEZ B;  3GMH A;  3ABD A;  1DUJ A;  4TZN A;  4EXT C;  4GK0 A;  4TZM A;  4J2G A;  5LCW Z;  2QYF A;  2V64 D;  4YK8 B;  4FJO C;  1KLQ A;  4TZL A;  3VU7 C;  4TRK A;  1S2H A;  4TZO A;  2VFX A;  4GK5 A;  4TZS A;  5C50 B;  3ABE C; 
#chains in the Genus database with same CATH homology
 2QYF B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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