2EIKA

Cadmium ion binding structure of bovine heart cytochrome c oxidase in the fully reduced state
Total Genus 208
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
208
sequence length
513
structure length
513
Chain Sequence
FINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A histidine residue acting as a controlling site for dioxygen reduction and proton pumping by cytochrome c oxidase
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Cytochrome c oxidase subunit 1
total genus 208
structure length 513
sequence length 513
chains with identical sequence N
ec nomenclature ec 1.9.3.1: Cytochrome-c oxidase.
pdb deposition date 2007-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00115 COX1 Cytochrome C and Quinol oxidase polypeptide I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase; Chain A Cytochrome c oxidase-like, subunit I domain 2eikA00
4G7SA 3ASOA 3S3BA 3AG4A 4GP8A 4FAAA 3WFDB 3WFCB 3WG7A 3EHBA 3QJUA 3AYFA 1XMEA 3O0RB 1EHKA 3MK7A 5B3SA 3ABKA 3QJSA 4FA7A 5IY5A 2EIKA 3WFBB 4XYDA 3FYEA 3QJTA 3OMNA 1V54A 3S8FA 3HB3A 4N4YA 1OCCA 2QPDA 2DYSA 3EH3A 2ZXWA 4G7RA 4GP5A 2QPEA 1M57A 4GP4A 3AG3A 3AG1A 3DTUA 2EIJA 1AR1A 3S3DA 5B1AA 2OCCA 3EH4A 3ABMA 5DJQA 2GSMA 3QJQA 3QJVA 2EIMA 1V55A 1OCRA 1M56A 2YEVA 3S8GA 4G7QA 3OM3A 3S3CA 3WFEB 3EH5A 5B1BA 2DYRA 3FYIA 3AG2A 1OCZA 3QJRA 1QLEA 3X2QA 4G70A 3AYGA 1OCOA 4G72A 3OMAA 2EINA 3ASNA 3OMIA 1FFTA 3ABLA 4G71A 2EILA 2Y69A 3BVDA
chains in the Genus database with same CATH superfamily
4G7SA 3ASOA 3S3BA 3AG4A 4GP8A 4FAAA 3WFDB 3WFCB 3WG7A 3EHBA 3QJUA 3AYFA 1XMEA 3O0RB 1EHKA 3MK7A 5B3SA 3ABKA 3QJSA 4FA7A 5IY5A 2EIKA 3WFBB 4XYDA 3FYEA 3QJTA 3OMNA 1V54A 3S8FA 3HB3A 4N4YA 1OCCA 2QPDA 2DYSA 3EH3A 2ZXWA 4G7RA 4GP5A 2QPEA 1M57A 4GP4A 3AG3A 3AG1A 3DTUA 2EIJA 1AR1A 3S3DA 5B1AA 2OCCA 3EH4A 3ABMA 5DJQA 2GSMA 3QJQA 3QJVA 2EIMA 1V55A 1OCRA 1M56A 2YEVA 3S8GA 4G7QA 3OM3A 3S3CA 3WFEB 3EH5A 5B1BA 2DYRA 3FYIA 3AG2A 1OCZA 3QJRA 1QLEA 3X2QA 4G70A 3AYGA 1OCOA 4G72A 3OMAA 2EINA 3ASNA 3OMIA 1FFTA 3ABLA 4G71A 2EILA 2Y69A 3BVDA
chains in the Genus database with same CATH topology
4G7SA 3ASOA 3S3BA 3AG4A 4GP8A 4FAAA 3WFDB 3WFCB 3WG7A 3EHBA 3QJUA 3AYFA 1XMEA 3O0RB 1EHKA 3MK7A 5B3SA 3ABKA 3QJSA 4FA7A 5IY5A 2EIKA 3WFBB 4XYDA 3FYEA 3QJTA 3OMNA 1V54A 3S8FA 3HB3A 4N4YA 1OCCA 2QPDA 2DYSA 3EH3A 2ZXWA 4G7RA 4GP5A 2QPEA 1M57A 4GP4A 3AG3A 3AG1A 3DTUA 2EIJA 1AR1A 3S3DA 5B1AA 2OCCA 3EH4A 3ABMA 5DJQA 2GSMA 3QJQA 3QJVA 2EIMA 1V55A 1OCRA 1M56A 2YEVA 3S8GA 4G7QA 3OM3A 3S3CA 3WFEB 3EH5A 5B1BA 2DYRA 3FYIA 3AG2A 1OCZA 3QJRA 1QLEA 3X2QA 4G70A 3AYGA 1OCOA 4G72A 3OMAA 2EINA 3ASNA 3OMIA 1FFTA 3ABLA 4G71A 2EILA 2Y69A 3BVDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4G7S A;  3ASO A;  3S3B A;  3AG4 A;  4GP8 A;  4FAA A;  3WFD B;  3WFC B;  3WG7 A;  3EHB A;  3QJU A;  3AYF A;  1XME A;  3O0R B;  1EHK A;  3MK7 A;  5B3S A;  3ABK A;  3QJS A;  4FA7 A;  5IY5 A;  2EIK A;  3WFB B;  4XYD A;  3FYE A;  3QJT A;  3OMN A;  1V54 A;  3S8F A;  3HB3 A;  4N4Y A;  1OCC A;  2QPD A;  2DYS A;  3EH3 A;  2ZXW A;  4G7R A;  4GP5 A;  2QPE A;  1M57 A;  4GP4 A;  3AG3 A;  3AG1 A;  3DTU A;  2EIJ A;  1AR1 A;  3S3D A;  5B1A A;  2OCC A;  3EH4 A;  3ABM A;  5DJQ A;  2GSM A;  3QJQ A;  3QJV A;  2EIM A;  1V55 A;  1OCR A;  1M56 A;  2YEV A;  3S8G A;  4G7Q A;  3OM3 A;  3S3C A;  3WFE B;  3EH5 A;  5B1B A;  2DYR A;  3FYI A;  3AG2 A;  1OCZ A;  3QJR A;  1QLE A;  3X2Q A;  4G70 A;  3AYG A;  1OCO A;  4G72 A;  3OMA A;  2EIN A;  3ASN A;  3OMI A;  1FFT A;  3ABL A;  4G71 A;  2EIL A;  2Y69 A;  3BVD A; 
#chains in the Genus database with same CATH topology
 4G7S A;  3ASO A;  3S3B A;  3AG4 A;  4GP8 A;  4FAA A;  3WFD B;  3WFC B;  3WG7 A;  3EHB A;  3QJU A;  3AYF A;  1XME A;  3O0R B;  1EHK A;  3MK7 A;  5B3S A;  3ABK A;  3QJS A;  4FA7 A;  5IY5 A;  2EIK A;  3WFB B;  4XYD A;  3FYE A;  3QJT A;  3OMN A;  1V54 A;  3S8F A;  3HB3 A;  4N4Y A;  1OCC A;  2QPD A;  2DYS A;  3EH3 A;  2ZXW A;  4G7R A;  4GP5 A;  2QPE A;  1M57 A;  4GP4 A;  3AG3 A;  3AG1 A;  3DTU A;  2EIJ A;  1AR1 A;  3S3D A;  5B1A A;  2OCC A;  3EH4 A;  3ABM A;  5DJQ A;  2GSM A;  3QJQ A;  3QJV A;  2EIM A;  1V55 A;  1OCR A;  1M56 A;  2YEV A;  3S8G A;  4G7Q A;  3OM3 A;  3S3C A;  3WFE B;  3EH5 A;  5B1B A;  2DYR A;  3FYI A;  3AG2 A;  1OCZ A;  3QJR A;  1QLE A;  3X2Q A;  4G70 A;  3AYG A;  1OCO A;  4G72 A;  3OMA A;  2EIN A;  3ASN A;  3OMI A;  1FFT A;  3ABL A;  4G71 A;  2EIL A;  2Y69 A;  3BVD A; 
#chains in the Genus database with same CATH homology
 4G7S A;  3ASO A;  3S3B A;  3AG4 A;  4GP8 A;  4FAA A;  3WFD B;  3WFC B;  3WG7 A;  3EHB A;  3QJU A;  3AYF A;  1XME A;  3O0R B;  1EHK A;  3MK7 A;  5B3S A;  3ABK A;  3QJS A;  4FA7 A;  5IY5 A;  2EIK A;  3WFB B;  4XYD A;  3FYE A;  3QJT A;  3OMN A;  1V54 A;  3S8F A;  3HB3 A;  4N4Y A;  1OCC A;  2QPD A;  2DYS A;  3EH3 A;  2ZXW A;  4G7R A;  4GP5 A;  2QPE A;  1M57 A;  4GP4 A;  3AG3 A;  3AG1 A;  3DTU A;  2EIJ A;  1AR1 A;  3S3D A;  5B1A A;  2OCC A;  3EH4 A;  3ABM A;  5DJQ A;  2GSM A;  3QJQ A;  3QJV A;  2EIM A;  1V55 A;  1OCR A;  1M56 A;  2YEV A;  3S8G A;  4G7Q A;  3OM3 A;  3S3C A;  3WFE B;  3EH5 A;  5B1B A;  2DYR A;  3FYI A;  3AG2 A;  1OCZ A;  3QJR A;  1QLE A;  3X2Q A;  4G70 A;  3AYG A;  1OCO A;  4G72 A;  3OMA A;  2EIN A;  3ASN A;  3OMI A;  1FFT A;  3ABL A;  4G71 A;  2EIL A;  2Y69 A;  3BVD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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