2EIMA

Zinc ion binding structure of bovine heart cytochrome c oxidase in the fully reduced state
Total Genus 209
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
209
sequence length
513
structure length
513
Chain Sequence
FINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A histidine residue acting as a controlling site for dioxygen reduction and proton pumping by cytochrome c oxidase
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Cytochrome c oxidase subunit 1
total genus 209
structure length 513
sequence length 513
chains with identical sequence N
ec nomenclature ec 1.9.3.1: Cytochrome-c oxidase.
pdb deposition date 2007-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00115 COX1 Cytochrome C and Quinol oxidase polypeptide I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase; Chain A Cytochrome c oxidase-like, subunit I domain 2eimA00
3S8GA 3BVDA 1M57A 4FAAA 2EIKA 3MK7A 3QJRA 2EIJA 3AG2A 4G72A 4FA7A 3S8FA 3WFEB 4G7QA 3ASNA 3DTUA 5DJQA 3OMNA 4G71A 3QJUA 2QPEA 1XMEA 1OCZA 3AG1A 4N4YA 2YEVA 1FFTA 4GP8A 3FYIA 1AR1A 4G7SA 3AG3A 1QLEA 2Y69A 2EIMA 3AG4A 2GSMA 3ASOA 3S3BA 3QJVA 2DYSA 3WFDB 3OMAA 4XYDA 2OCCA 3WFCB 3HB3A 3ABMA 1M56A 3S3DA 3AYGA 1OCRA 1V54A 3WG7A 1EHKA 4GP4A 3FYEA 3OM3A 5B1AA 4G70A 3X2QA 3AYFA 3S3CA 1OCCA 4GP5A 3EH5A 3EH4A 3EH3A 2ZXWA 3EHBA 3OMIA 3ABLA 1OCOA 3O0RB 3QJQA 3WFBB 3QJSA 3ABKA 5B1BA 5B3SA 2QPDA 2EINA 2EILA 5IY5A 1V55A 4G7RA 3QJTA 2DYRA
chains in the Genus database with same CATH superfamily
3S8GA 3BVDA 1M57A 4FAAA 2EIKA 3MK7A 3QJRA 2EIJA 3AG2A 4G72A 4FA7A 3S8FA 3WFEB 4G7QA 3ASNA 3DTUA 5DJQA 3OMNA 4G71A 3QJUA 2QPEA 1XMEA 1OCZA 3AG1A 4N4YA 2YEVA 1FFTA 4GP8A 3FYIA 1AR1A 4G7SA 3AG3A 1QLEA 2Y69A 2EIMA 3AG4A 2GSMA 3ASOA 3S3BA 3QJVA 2DYSA 3WFDB 3OMAA 4XYDA 2OCCA 3WFCB 3HB3A 3ABMA 1M56A 3S3DA 3AYGA 1OCRA 1V54A 3WG7A 1EHKA 4GP4A 3FYEA 3OM3A 5B1AA 4G70A 3X2QA 3AYFA 3S3CA 1OCCA 4GP5A 3EH5A 3EH4A 3EH3A 2ZXWA 3EHBA 3OMIA 3ABLA 1OCOA 3O0RB 3QJQA 3WFBB 3QJSA 3ABKA 5B1BA 5B3SA 2QPDA 2EINA 2EILA 5IY5A 1V55A 4G7RA 3QJTA 2DYRA
chains in the Genus database with same CATH topology
3S8GA 3BVDA 1M57A 4FAAA 2EIKA 3MK7A 3QJRA 2EIJA 3AG2A 4G72A 4FA7A 3S8FA 3WFEB 4G7QA 3ASNA 3DTUA 5DJQA 3OMNA 4G71A 3QJUA 2QPEA 1XMEA 1OCZA 3AG1A 4N4YA 2YEVA 1FFTA 4GP8A 3FYIA 1AR1A 4G7SA 3AG3A 1QLEA 2Y69A 2EIMA 3AG4A 2GSMA 3ASOA 3S3BA 3QJVA 2DYSA 3WFDB 3OMAA 4XYDA 2OCCA 3WFCB 3HB3A 3ABMA 1M56A 3S3DA 3AYGA 1OCRA 1V54A 3WG7A 1EHKA 4GP4A 3FYEA 3OM3A 5B1AA 4G70A 3X2QA 3AYFA 3S3CA 1OCCA 4GP5A 3EH5A 3EH4A 3EH3A 2ZXWA 3EHBA 3OMIA 3ABLA 1OCOA 3O0RB 3QJQA 3WFBB 3QJSA 3ABKA 5B1BA 5B3SA 2QPDA 2EINA 2EILA 5IY5A 1V55A 4G7RA 3QJTA 2DYRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S8G A;  3BVD A;  1M57 A;  4FAA A;  2EIK A;  3MK7 A;  3QJR A;  2EIJ A;  3AG2 A;  4G72 A;  4FA7 A;  3S8F A;  3WFE B;  4G7Q A;  3ASN A;  3DTU A;  5DJQ A;  3OMN A;  4G71 A;  3QJU A;  2QPE A;  1XME A;  1OCZ A;  3AG1 A;  4N4Y A;  2YEV A;  1FFT A;  4GP8 A;  3FYI A;  1AR1 A;  4G7S A;  3AG3 A;  1QLE A;  2Y69 A;  2EIM A;  3AG4 A;  2GSM A;  3ASO A;  3S3B A;  3QJV A;  2DYS A;  3WFD B;  3OMA A;  4XYD A;  2OCC A;  3WFC B;  3HB3 A;  3ABM A;  1M56 A;  3S3D A;  3AYG A;  1OCR A;  1V54 A;  3WG7 A;  1EHK A;  4GP4 A;  3FYE A;  3OM3 A;  5B1A A;  4G70 A;  3X2Q A;  3AYF A;  3S3C A;  1OCC A;  4GP5 A;  3EH5 A;  3EH4 A;  3EH3 A;  2ZXW A;  3EHB A;  3OMI A;  3ABL A;  1OCO A;  3O0R B;  3QJQ A;  3WFB B;  3QJS A;  3ABK A;  5B1B A;  5B3S A;  2QPD A;  2EIN A;  2EIL A;  5IY5 A;  1V55 A;  4G7R A;  3QJT A;  2DYR A; 
#chains in the Genus database with same CATH topology
 3S8G A;  3BVD A;  1M57 A;  4FAA A;  2EIK A;  3MK7 A;  3QJR A;  2EIJ A;  3AG2 A;  4G72 A;  4FA7 A;  3S8F A;  3WFE B;  4G7Q A;  3ASN A;  3DTU A;  5DJQ A;  3OMN A;  4G71 A;  3QJU A;  2QPE A;  1XME A;  1OCZ A;  3AG1 A;  4N4Y A;  2YEV A;  1FFT A;  4GP8 A;  3FYI A;  1AR1 A;  4G7S A;  3AG3 A;  1QLE A;  2Y69 A;  2EIM A;  3AG4 A;  2GSM A;  3ASO A;  3S3B A;  3QJV A;  2DYS A;  3WFD B;  3OMA A;  4XYD A;  2OCC A;  3WFC B;  3HB3 A;  3ABM A;  1M56 A;  3S3D A;  3AYG A;  1OCR A;  1V54 A;  3WG7 A;  1EHK A;  4GP4 A;  3FYE A;  3OM3 A;  5B1A A;  4G70 A;  3X2Q A;  3AYF A;  3S3C A;  1OCC A;  4GP5 A;  3EH5 A;  3EH4 A;  3EH3 A;  2ZXW A;  3EHB A;  3OMI A;  3ABL A;  1OCO A;  3O0R B;  3QJQ A;  3WFB B;  3QJS A;  3ABK A;  5B1B A;  5B3S A;  2QPD A;  2EIN A;  2EIL A;  5IY5 A;  1V55 A;  4G7R A;  3QJT A;  2DYR A; 
#chains in the Genus database with same CATH homology
 3S8G A;  3BVD A;  1M57 A;  4FAA A;  2EIK A;  3MK7 A;  3QJR A;  2EIJ A;  3AG2 A;  4G72 A;  4FA7 A;  3S8F A;  3WFE B;  4G7Q A;  3ASN A;  3DTU A;  5DJQ A;  3OMN A;  4G71 A;  3QJU A;  2QPE A;  1XME A;  1OCZ A;  3AG1 A;  4N4Y A;  2YEV A;  1FFT A;  4GP8 A;  3FYI A;  1AR1 A;  4G7S A;  3AG3 A;  1QLE A;  2Y69 A;  2EIM A;  3AG4 A;  2GSM A;  3ASO A;  3S3B A;  3QJV A;  2DYS A;  3WFD B;  3OMA A;  4XYD A;  2OCC A;  3WFC B;  3HB3 A;  3ABM A;  1M56 A;  3S3D A;  3AYG A;  1OCR A;  1V54 A;  3WG7 A;  1EHK A;  4GP4 A;  3FYE A;  3OM3 A;  5B1A A;  4G70 A;  3X2Q A;  3AYF A;  3S3C A;  1OCC A;  4GP5 A;  3EH5 A;  3EH4 A;  3EH3 A;  2ZXW A;  3EHB A;  3OMI A;  3ABL A;  1OCO A;  3O0R B;  3QJQ A;  3WFB B;  3QJS A;  3ABK A;  5B1B A;  5B3S A;  2QPD A;  2EIN A;  2EIL A;  5IY5 A;  1V55 A;  4G7R A;  3QJT A;  2DYR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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