2EINA

Zinc ion binding structure of bovine heart cytochrome c oxidase in the fully oxidized state
Total Genus 202
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
202
sequence length
513
structure length
513
Chain Sequence
FINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A histidine residue acting as a controlling site for dioxygen reduction and proton pumping by cytochrome c oxidase
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Cytochrome c oxidase subunit 1
total genus 202
structure length 513
sequence length 513
chains with identical sequence N
ec nomenclature ec 1.9.3.1: Cytochrome-c oxidase.
pdb deposition date 2007-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00115 COX1 Cytochrome C and Quinol oxidase polypeptide I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase; Chain A Cytochrome c oxidase-like, subunit I domain 2einA00
3HB3A 4GP4A 5B1AA 3AG2A 4G70A 2EIKA 1QLEA 3WFDB 3X2QA 5B3SA 3ABKA 2EINA 3EHBA 1V54A 3BVDA 3ABLA 4FA7A 2OCCA 3AG1A 1EHKA 5B1BA 4G7SA 3QJVA 3S8FA 2DYRA 2Y69A 1AR1A 3WFEB 4G72A 3S3DA 1M56A 3AYGA 3S3CA 5DJQA 1OCCA 3AYFA 2QPEA 4XYDA 3S8GA 3FYIA 3OM3A 3QJRA 1V55A 4G7QA 3DTUA 3FYEA 4GP8A 1XMEA 3OMNA 3EH5A 3S3BA 2EILA 2DYSA 1FFTA 4GP5A 3EH3A 3AG3A 2ZXWA 3EH4A 3ASNA 3WFCB 4FAAA 2GSMA 5IY5A 3O0RB 2EIJA 3MK7A 1OCRA 3QJSA 3QJTA 3AG4A 3QJQA 3QJUA 4G7RA 1OCOA 1OCZA 3ASOA 4G71A 2QPDA 1M57A 3OMAA 3WG7A 3ABMA 3WFBB 2YEVA 4N4YA 3OMIA 2EIMA
chains in the Genus database with same CATH superfamily
3HB3A 4GP4A 5B1AA 3AG2A 4G70A 2EIKA 1QLEA 3WFDB 3X2QA 5B3SA 3ABKA 2EINA 3EHBA 1V54A 3BVDA 3ABLA 4FA7A 2OCCA 3AG1A 1EHKA 5B1BA 4G7SA 3QJVA 3S8FA 2DYRA 2Y69A 1AR1A 3WFEB 4G72A 3S3DA 1M56A 3AYGA 3S3CA 5DJQA 1OCCA 3AYFA 2QPEA 4XYDA 3S8GA 3FYIA 3OM3A 3QJRA 1V55A 4G7QA 3DTUA 3FYEA 4GP8A 1XMEA 3OMNA 3EH5A 3S3BA 2EILA 2DYSA 1FFTA 4GP5A 3EH3A 3AG3A 2ZXWA 3EH4A 3ASNA 3WFCB 4FAAA 2GSMA 5IY5A 3O0RB 2EIJA 3MK7A 1OCRA 3QJSA 3QJTA 3AG4A 3QJQA 3QJUA 4G7RA 1OCOA 1OCZA 3ASOA 4G71A 2QPDA 1M57A 3OMAA 3WG7A 3ABMA 3WFBB 2YEVA 4N4YA 3OMIA 2EIMA
chains in the Genus database with same CATH topology
3HB3A 4GP4A 5B1AA 3AG2A 4G70A 2EIKA 1QLEA 3WFDB 3X2QA 5B3SA 3ABKA 2EINA 3EHBA 1V54A 3BVDA 3ABLA 4FA7A 2OCCA 3AG1A 1EHKA 5B1BA 4G7SA 3QJVA 3S8FA 2DYRA 2Y69A 1AR1A 3WFEB 4G72A 3S3DA 1M56A 3AYGA 3S3CA 5DJQA 1OCCA 3AYFA 2QPEA 4XYDA 3S8GA 3FYIA 3OM3A 3QJRA 1V55A 4G7QA 3DTUA 3FYEA 4GP8A 1XMEA 3OMNA 3EH5A 3S3BA 2EILA 2DYSA 1FFTA 4GP5A 3EH3A 3AG3A 2ZXWA 3EH4A 3ASNA 3WFCB 4FAAA 2GSMA 5IY5A 3O0RB 2EIJA 3MK7A 1OCRA 3QJSA 3QJTA 3AG4A 3QJQA 3QJUA 4G7RA 1OCOA 1OCZA 3ASOA 4G71A 2QPDA 1M57A 3OMAA 3WG7A 3ABMA 3WFBB 2YEVA 4N4YA 3OMIA 2EIMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HB3 A;  4GP4 A;  5B1A A;  3AG2 A;  4G70 A;  2EIK A;  1QLE A;  3WFD B;  3X2Q A;  5B3S A;  3ABK A;  2EIN A;  3EHB A;  1V54 A;  3BVD A;  3ABL A;  4FA7 A;  2OCC A;  3AG1 A;  1EHK A;  5B1B A;  4G7S A;  3QJV A;  3S8F A;  2DYR A;  2Y69 A;  1AR1 A;  3WFE B;  4G72 A;  3S3D A;  1M56 A;  3AYG A;  3S3C A;  5DJQ A;  1OCC A;  3AYF A;  2QPE A;  4XYD A;  3S8G A;  3FYI A;  3OM3 A;  3QJR A;  1V55 A;  4G7Q A;  3DTU A;  3FYE A;  4GP8 A;  1XME A;  3OMN A;  3EH5 A;  3S3B A;  2EIL A;  2DYS A;  1FFT A;  4GP5 A;  3EH3 A;  3AG3 A;  2ZXW A;  3EH4 A;  3ASN A;  3WFC B;  4FAA A;  2GSM A;  5IY5 A;  3O0R B;  2EIJ A;  3MK7 A;  1OCR A;  3QJS A;  3QJT A;  3AG4 A;  3QJQ A;  3QJU A;  4G7R A;  1OCO A;  1OCZ A;  3ASO A;  4G71 A;  2QPD A;  1M57 A;  3OMA A;  3WG7 A;  3ABM A;  3WFB B;  2YEV A;  4N4Y A;  3OMI A;  2EIM A; 
#chains in the Genus database with same CATH topology
 3HB3 A;  4GP4 A;  5B1A A;  3AG2 A;  4G70 A;  2EIK A;  1QLE A;  3WFD B;  3X2Q A;  5B3S A;  3ABK A;  2EIN A;  3EHB A;  1V54 A;  3BVD A;  3ABL A;  4FA7 A;  2OCC A;  3AG1 A;  1EHK A;  5B1B A;  4G7S A;  3QJV A;  3S8F A;  2DYR A;  2Y69 A;  1AR1 A;  3WFE B;  4G72 A;  3S3D A;  1M56 A;  3AYG A;  3S3C A;  5DJQ A;  1OCC A;  3AYF A;  2QPE A;  4XYD A;  3S8G A;  3FYI A;  3OM3 A;  3QJR A;  1V55 A;  4G7Q A;  3DTU A;  3FYE A;  4GP8 A;  1XME A;  3OMN A;  3EH5 A;  3S3B A;  2EIL A;  2DYS A;  1FFT A;  4GP5 A;  3EH3 A;  3AG3 A;  2ZXW A;  3EH4 A;  3ASN A;  3WFC B;  4FAA A;  2GSM A;  5IY5 A;  3O0R B;  2EIJ A;  3MK7 A;  1OCR A;  3QJS A;  3QJT A;  3AG4 A;  3QJQ A;  3QJU A;  4G7R A;  1OCO A;  1OCZ A;  3ASO A;  4G71 A;  2QPD A;  1M57 A;  3OMA A;  3WG7 A;  3ABM A;  3WFB B;  2YEV A;  4N4Y A;  3OMI A;  2EIM A; 
#chains in the Genus database with same CATH homology
 3HB3 A;  4GP4 A;  5B1A A;  3AG2 A;  4G70 A;  2EIK A;  1QLE A;  3WFD B;  3X2Q A;  5B3S A;  3ABK A;  2EIN A;  3EHB A;  1V54 A;  3BVD A;  3ABL A;  4FA7 A;  2OCC A;  3AG1 A;  1EHK A;  5B1B A;  4G7S A;  3QJV A;  3S8F A;  2DYR A;  2Y69 A;  1AR1 A;  3WFE B;  4G72 A;  3S3D A;  1M56 A;  3AYG A;  3S3C A;  5DJQ A;  1OCC A;  3AYF A;  2QPE A;  4XYD A;  3S8G A;  3FYI A;  3OM3 A;  3QJR A;  1V55 A;  4G7Q A;  3DTU A;  3FYE A;  4GP8 A;  1XME A;  3OMN A;  3EH5 A;  3S3B A;  2EIL A;  2DYS A;  1FFT A;  4GP5 A;  3EH3 A;  3AG3 A;  2ZXW A;  3EH4 A;  3ASN A;  3WFC B;  4FAA A;  2GSM A;  5IY5 A;  3O0R B;  2EIJ A;  3MK7 A;  1OCR A;  3QJS A;  3QJT A;  3AG4 A;  3QJQ A;  3QJU A;  4G7R A;  1OCO A;  1OCZ A;  3ASO A;  4G71 A;  2QPD A;  1M57 A;  3OMA A;  3WG7 A;  3ABM A;  3WFB B;  2YEV A;  4N4Y A;  3OMI A;  2EIM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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