2GSMA

Catalytic core (subunits i and ii) of cytochrome c oxidase from rhodobacter sphaeroides
Total Genus 223
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
223
sequence length
535
structure length
535
Chain Sequence
FTRWFMSTNHKDIGVLYLFTGGLVGLISVAFTVYMRMELMAPGVQFMCAEHLESGLVKGFFQSLWPSAVENCTPNGHLWNVMITGHGILMMFFVVIPALFGGFGNYFMPLHIGAPDMAFPRMNNLSYWLYVAGTSLAVASLFAPGGNGQLGSGIGWVLYPPLSTSESGYSTDLAIFAVHLSGASSILGAINMITTFLNMRAPGMTMHKVPLFAWSIFVTAWLILLALPVLAGAITMLLTDRNFGTTFFQPSGGGDPVLYQHILWFFGHPEVYIIVLPAFGIVSHVIATFAKKPIFGYLPMVYAMVAIGVLGFVVWAHHMYTAGLSLTQQSYFMMATMVIAVPTGIKIFSWIATMWGGSIELKTPMLWALGFLFLFTVGGVTGIVLSQASVDRYYHDTYYVVAHFHYVMSLGAVFGIFAGIYFWIGKMSGRQYPEWAGKLHFWMMFVGANLTFFPQHFLGRQGMPRRYIDYPEAFATWNFVSSLGAFLSFASFLFFLGVIFYTLTRGARVTANNYWNEHADTLEWTLTSPPPEHTF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of conserved lipid/detergent-binding sites in a high-resolution structure of the membrane protein cytochrome c oxidase.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Rhodobacter sphaeroides
molecule keywords Cytochrome c oxidase subunit 1
total genus 223
structure length 535
sequence length 535
chains with identical sequence C
ec nomenclature ec 1.9.3.1: Cytochrome-c oxidase.
pdb deposition date 2006-04-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00115 COX1 Cytochrome C and Quinol oxidase polypeptide I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase; Chain A Cytochrome c oxidase-like, subunit I domain 2gsmA00
4FAAA 3ASNA 4N4YA 1FFTA 1OCRA 2GSMA 3S3CA 3AG4A 1OCOA 2QPEA 3QJUA 2EIMA 3S3DA 5IY5A 4G71A 3WFBB 2OCCA 1M57A 3AG2A 3DTUA 3QJVA 3ABLA 1XMEA 3ABMA 4G7QA 3EH5A 3EH3A 4GP5A 3OMAA 1V55A 3QJSA 3OMIA 2QPDA 3HB3A 4G7SA 3FYEA 1OCZA 5B1AA 3WFCB 3OM3A 4GP4A 3WG7A 3EH4A 3BVDA 3WFEB 4G72A 2DYSA 2EINA 3OMNA 2EIKA 3AYFA 4FA7A 3AG1A 3MK7A 4GP8A 2Y69A 2YEVA 1QLEA 3ABKA 4G7RA 3FYIA 1AR1A 3WFDB 1EHKA 1OCCA 2ZXWA 2EILA 3QJRA 5B3SA 3QJQA 3X2QA 3EHBA 3QJTA 3S8FA 4G70A 3AYGA 3S8GA 4XYDA 2EIJA 1V54A 3O0RB 5B1BA 1M56A 2DYRA 3AG3A 3ASOA 5DJQA 3S3BA
chains in the Genus database with same CATH superfamily
4FAAA 3ASNA 4N4YA 1FFTA 1OCRA 2GSMA 3S3CA 3AG4A 1OCOA 2QPEA 3QJUA 2EIMA 3S3DA 5IY5A 4G71A 3WFBB 2OCCA 1M57A 3AG2A 3DTUA 3QJVA 3ABLA 1XMEA 3ABMA 4G7QA 3EH5A 3EH3A 4GP5A 3OMAA 1V55A 3QJSA 3OMIA 2QPDA 3HB3A 4G7SA 3FYEA 1OCZA 5B1AA 3WFCB 3OM3A 4GP4A 3WG7A 3EH4A 3BVDA 3WFEB 4G72A 2DYSA 2EINA 3OMNA 2EIKA 3AYFA 4FA7A 3AG1A 3MK7A 4GP8A 2Y69A 2YEVA 1QLEA 3ABKA 4G7RA 3FYIA 1AR1A 3WFDB 1EHKA 1OCCA 2ZXWA 2EILA 3QJRA 5B3SA 3QJQA 3X2QA 3EHBA 3QJTA 3S8FA 4G70A 3AYGA 3S8GA 4XYDA 2EIJA 1V54A 3O0RB 5B1BA 1M56A 2DYRA 3AG3A 3ASOA 5DJQA 3S3BA
chains in the Genus database with same CATH topology
4FAAA 3ASNA 4N4YA 1FFTA 1OCRA 2GSMA 3S3CA 3AG4A 1OCOA 2QPEA 3QJUA 2EIMA 3S3DA 5IY5A 4G71A 3WFBB 2OCCA 1M57A 3AG2A 3DTUA 3QJVA 3ABLA 1XMEA 3ABMA 4G7QA 3EH5A 3EH3A 4GP5A 3OMAA 1V55A 3QJSA 3OMIA 2QPDA 3HB3A 4G7SA 3FYEA 1OCZA 5B1AA 3WFCB 3OM3A 4GP4A 3WG7A 3EH4A 3BVDA 3WFEB 4G72A 2DYSA 2EINA 3OMNA 2EIKA 3AYFA 4FA7A 3AG1A 3MK7A 4GP8A 2Y69A 2YEVA 1QLEA 3ABKA 4G7RA 3FYIA 1AR1A 3WFDB 1EHKA 1OCCA 2ZXWA 2EILA 3QJRA 5B3SA 3QJQA 3X2QA 3EHBA 3QJTA 3S8FA 4G70A 3AYGA 3S8GA 4XYDA 2EIJA 1V54A 3O0RB 5B1BA 1M56A 2DYRA 3AG3A 3ASOA 5DJQA 3S3BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FAA A;  3ASN A;  4N4Y A;  1FFT A;  1OCR A;  2GSM A;  3S3C A;  3AG4 A;  1OCO A;  2QPE A;  3QJU A;  2EIM A;  3S3D A;  5IY5 A;  4G71 A;  3WFB B;  2OCC A;  1M57 A;  3AG2 A;  3DTU A;  3QJV A;  3ABL A;  1XME A;  3ABM A;  4G7Q A;  3EH5 A;  3EH3 A;  4GP5 A;  3OMA A;  1V55 A;  3QJS A;  3OMI A;  2QPD A;  3HB3 A;  4G7S A;  3FYE A;  1OCZ A;  5B1A A;  3WFC B;  3OM3 A;  4GP4 A;  3WG7 A;  3EH4 A;  3BVD A;  3WFE B;  4G72 A;  2DYS A;  2EIN A;  3OMN A;  2EIK A;  3AYF A;  4FA7 A;  3AG1 A;  3MK7 A;  4GP8 A;  2Y69 A;  2YEV A;  1QLE A;  3ABK A;  4G7R A;  3FYI A;  1AR1 A;  3WFD B;  1EHK A;  1OCC A;  2ZXW A;  2EIL A;  3QJR A;  5B3S A;  3QJQ A;  3X2Q A;  3EHB A;  3QJT A;  3S8F A;  4G70 A;  3AYG A;  3S8G A;  4XYD A;  2EIJ A;  1V54 A;  3O0R B;  5B1B A;  1M56 A;  2DYR A;  3AG3 A;  3ASO A;  5DJQ A;  3S3B A; 
#chains in the Genus database with same CATH topology
 4FAA A;  3ASN A;  4N4Y A;  1FFT A;  1OCR A;  2GSM A;  3S3C A;  3AG4 A;  1OCO A;  2QPE A;  3QJU A;  2EIM A;  3S3D A;  5IY5 A;  4G71 A;  3WFB B;  2OCC A;  1M57 A;  3AG2 A;  3DTU A;  3QJV A;  3ABL A;  1XME A;  3ABM A;  4G7Q A;  3EH5 A;  3EH3 A;  4GP5 A;  3OMA A;  1V55 A;  3QJS A;  3OMI A;  2QPD A;  3HB3 A;  4G7S A;  3FYE A;  1OCZ A;  5B1A A;  3WFC B;  3OM3 A;  4GP4 A;  3WG7 A;  3EH4 A;  3BVD A;  3WFE B;  4G72 A;  2DYS A;  2EIN A;  3OMN A;  2EIK A;  3AYF A;  4FA7 A;  3AG1 A;  3MK7 A;  4GP8 A;  2Y69 A;  2YEV A;  1QLE A;  3ABK A;  4G7R A;  3FYI A;  1AR1 A;  3WFD B;  1EHK A;  1OCC A;  2ZXW A;  2EIL A;  3QJR A;  5B3S A;  3QJQ A;  3X2Q A;  3EHB A;  3QJT A;  3S8F A;  4G70 A;  3AYG A;  3S8G A;  4XYD A;  2EIJ A;  1V54 A;  3O0R B;  5B1B A;  1M56 A;  2DYR A;  3AG3 A;  3ASO A;  5DJQ A;  3S3B A; 
#chains in the Genus database with same CATH homology
 4FAA A;  3ASN A;  4N4Y A;  1FFT A;  1OCR A;  2GSM A;  3S3C A;  3AG4 A;  1OCO A;  2QPE A;  3QJU A;  2EIM A;  3S3D A;  5IY5 A;  4G71 A;  3WFB B;  2OCC A;  1M57 A;  3AG2 A;  3DTU A;  3QJV A;  3ABL A;  1XME A;  3ABM A;  4G7Q A;  3EH5 A;  3EH3 A;  4GP5 A;  3OMA A;  1V55 A;  3QJS A;  3OMI A;  2QPD A;  3HB3 A;  4G7S A;  3FYE A;  1OCZ A;  5B1A A;  3WFC B;  3OM3 A;  4GP4 A;  3WG7 A;  3EH4 A;  3BVD A;  3WFE B;  4G72 A;  2DYS A;  2EIN A;  3OMN A;  2EIK A;  3AYF A;  4FA7 A;  3AG1 A;  3MK7 A;  4GP8 A;  2Y69 A;  2YEV A;  1QLE A;  3ABK A;  4G7R A;  3FYI A;  1AR1 A;  3WFD B;  1EHK A;  1OCC A;  2ZXW A;  2EIL A;  3QJR A;  5B3S A;  3QJQ A;  3X2Q A;  3EHB A;  3QJT A;  3S8F A;  4G70 A;  3AYG A;  3S8G A;  4XYD A;  2EIJ A;  1V54 A;  3O0R B;  5B1B A;  1M56 A;  2DYR A;  3AG3 A;  3ASO A;  5DJQ A;  3S3B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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