3ABLA

Bovine heart cytochrome c oxidase at the fully oxidized state (15-s x-ray exposure dataset)
Total Genus 206
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
206
sequence length
513
structure length
513
Chain Sequence
FINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A peroxide bridge between Fe and Cu ions in the O2 reduction site of fully oxidized cytochrome c oxidase could suppress the proton pump
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Cytochrome c oxidase subunit 1
total genus 206
structure length 513
sequence length 513
chains with identical sequence N
ec nomenclature ec 1.9.3.1: Cytochrome-c oxidase.
pdb deposition date 2009-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00115 COX1 Cytochrome C and Quinol oxidase polypeptide I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase; Chain A Cytochrome c oxidase-like, subunit I domain 3ablA00
4GP5A 3AG2A 3ABMA 2EIJA 3AG4A 5DJQA 4N4YA 3FYIA 2GSMA 3WG7A 3X2QA 3WFDB 2EIMA 4FA7A 3EH4A 2DYRA 4G7QA 4XYDA 3QJQA 3QJRA 3MK7A 2DYSA 3O0RB 3DTUA 1XMEA 1V54A 4FAAA 4G7SA 5IY5A 4G72A 1OCRA 2YEVA 1EHKA 1OCCA 5B1AA 3EH5A 2OCCA 3ASNA 3S3CA 3ABLA 1AR1A 3QJSA 3ABKA 1QLEA 3OMIA 2EINA 2QPEA 3AG1A 1M56A 4G70A 2Y69A 3EHBA 3QJTA 3FYEA 3AYGA 1OCOA 3HB3A 2EILA 3EH3A 1M57A 2QPDA 3S8GA 3S3DA 3ASOA 3QJUA 1FFTA 3OMNA 4G7RA 3AYFA 3OMAA 5B1BA 2EIKA 3QJVA 3WFBB 3OM3A 3WFEB 1OCZA 2ZXWA 4GP8A 5B3SA 3BVDA 4GP4A 3WFCB 3S3BA 3S8FA 4G71A 3AG3A 1V55A
chains in the Genus database with same CATH superfamily
4GP5A 3AG2A 3ABMA 2EIJA 3AG4A 5DJQA 4N4YA 3FYIA 2GSMA 3WG7A 3X2QA 3WFDB 2EIMA 4FA7A 3EH4A 2DYRA 4G7QA 4XYDA 3QJQA 3QJRA 3MK7A 2DYSA 3O0RB 3DTUA 1XMEA 1V54A 4FAAA 4G7SA 5IY5A 4G72A 1OCRA 2YEVA 1EHKA 1OCCA 5B1AA 3EH5A 2OCCA 3ASNA 3S3CA 3ABLA 1AR1A 3QJSA 3ABKA 1QLEA 3OMIA 2EINA 2QPEA 3AG1A 1M56A 4G70A 2Y69A 3EHBA 3QJTA 3FYEA 3AYGA 1OCOA 3HB3A 2EILA 3EH3A 1M57A 2QPDA 3S8GA 3S3DA 3ASOA 3QJUA 1FFTA 3OMNA 4G7RA 3AYFA 3OMAA 5B1BA 2EIKA 3QJVA 3WFBB 3OM3A 3WFEB 1OCZA 2ZXWA 4GP8A 5B3SA 3BVDA 4GP4A 3WFCB 3S3BA 3S8FA 4G71A 3AG3A 1V55A
chains in the Genus database with same CATH topology
4GP5A 3AG2A 3ABMA 2EIJA 3AG4A 5DJQA 4N4YA 3FYIA 2GSMA 3WG7A 3X2QA 3WFDB 2EIMA 4FA7A 3EH4A 2DYRA 4G7QA 4XYDA 3QJQA 3QJRA 3MK7A 2DYSA 3O0RB 3DTUA 1XMEA 1V54A 4FAAA 4G7SA 5IY5A 4G72A 1OCRA 2YEVA 1EHKA 1OCCA 5B1AA 3EH5A 2OCCA 3ASNA 3S3CA 3ABLA 1AR1A 3QJSA 3ABKA 1QLEA 3OMIA 2EINA 2QPEA 3AG1A 1M56A 4G70A 2Y69A 3EHBA 3QJTA 3FYEA 3AYGA 1OCOA 3HB3A 2EILA 3EH3A 1M57A 2QPDA 3S8GA 3S3DA 3ASOA 3QJUA 1FFTA 3OMNA 4G7RA 3AYFA 3OMAA 5B1BA 2EIKA 3QJVA 3WFBB 3OM3A 3WFEB 1OCZA 2ZXWA 4GP8A 5B3SA 3BVDA 4GP4A 3WFCB 3S3BA 3S8FA 4G71A 3AG3A 1V55A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GP5 A;  3AG2 A;  3ABM A;  2EIJ A;  3AG4 A;  5DJQ A;  4N4Y A;  3FYI A;  2GSM A;  3WG7 A;  3X2Q A;  3WFD B;  2EIM A;  4FA7 A;  3EH4 A;  2DYR A;  4G7Q A;  4XYD A;  3QJQ A;  3QJR A;  3MK7 A;  2DYS A;  3O0R B;  3DTU A;  1XME A;  1V54 A;  4FAA A;  4G7S A;  5IY5 A;  4G72 A;  1OCR A;  2YEV A;  1EHK A;  1OCC A;  5B1A A;  3EH5 A;  2OCC A;  3ASN A;  3S3C A;  3ABL A;  1AR1 A;  3QJS A;  3ABK A;  1QLE A;  3OMI A;  2EIN A;  2QPE A;  3AG1 A;  1M56 A;  4G70 A;  2Y69 A;  3EHB A;  3QJT A;  3FYE A;  3AYG A;  1OCO A;  3HB3 A;  2EIL A;  3EH3 A;  1M57 A;  2QPD A;  3S8G A;  3S3D A;  3ASO A;  3QJU A;  1FFT A;  3OMN A;  4G7R A;  3AYF A;  3OMA A;  5B1B A;  2EIK A;  3QJV A;  3WFB B;  3OM3 A;  3WFE B;  1OCZ A;  2ZXW A;  4GP8 A;  5B3S A;  3BVD A;  4GP4 A;  3WFC B;  3S3B A;  3S8F A;  4G71 A;  3AG3 A;  1V55 A; 
#chains in the Genus database with same CATH topology
 4GP5 A;  3AG2 A;  3ABM A;  2EIJ A;  3AG4 A;  5DJQ A;  4N4Y A;  3FYI A;  2GSM A;  3WG7 A;  3X2Q A;  3WFD B;  2EIM A;  4FA7 A;  3EH4 A;  2DYR A;  4G7Q A;  4XYD A;  3QJQ A;  3QJR A;  3MK7 A;  2DYS A;  3O0R B;  3DTU A;  1XME A;  1V54 A;  4FAA A;  4G7S A;  5IY5 A;  4G72 A;  1OCR A;  2YEV A;  1EHK A;  1OCC A;  5B1A A;  3EH5 A;  2OCC A;  3ASN A;  3S3C A;  3ABL A;  1AR1 A;  3QJS A;  3ABK A;  1QLE A;  3OMI A;  2EIN A;  2QPE A;  3AG1 A;  1M56 A;  4G70 A;  2Y69 A;  3EHB A;  3QJT A;  3FYE A;  3AYG A;  1OCO A;  3HB3 A;  2EIL A;  3EH3 A;  1M57 A;  2QPD A;  3S8G A;  3S3D A;  3ASO A;  3QJU A;  1FFT A;  3OMN A;  4G7R A;  3AYF A;  3OMA A;  5B1B A;  2EIK A;  3QJV A;  3WFB B;  3OM3 A;  3WFE B;  1OCZ A;  2ZXW A;  4GP8 A;  5B3S A;  3BVD A;  4GP4 A;  3WFC B;  3S3B A;  3S8F A;  4G71 A;  3AG3 A;  1V55 A; 
#chains in the Genus database with same CATH homology
 4GP5 A;  3AG2 A;  3ABM A;  2EIJ A;  3AG4 A;  5DJQ A;  4N4Y A;  3FYI A;  2GSM A;  3WG7 A;  3X2Q A;  3WFD B;  2EIM A;  4FA7 A;  3EH4 A;  2DYR A;  4G7Q A;  4XYD A;  3QJQ A;  3QJR A;  3MK7 A;  2DYS A;  3O0R B;  3DTU A;  1XME A;  1V54 A;  4FAA A;  4G7S A;  5IY5 A;  4G72 A;  1OCR A;  2YEV A;  1EHK A;  1OCC A;  5B1A A;  3EH5 A;  2OCC A;  3ASN A;  3S3C A;  3ABL A;  1AR1 A;  3QJS A;  3ABK A;  1QLE A;  3OMI A;  2EIN A;  2QPE A;  3AG1 A;  1M56 A;  4G70 A;  2Y69 A;  3EHB A;  3QJT A;  3FYE A;  3AYG A;  1OCO A;  3HB3 A;  2EIL A;  3EH3 A;  1M57 A;  2QPD A;  3S8G A;  3S3D A;  3ASO A;  3QJU A;  1FFT A;  3OMN A;  4G7R A;  3AYF A;  3OMA A;  5B1B A;  2EIK A;  3QJV A;  3WFB B;  3OM3 A;  3WFE B;  1OCZ A;  2ZXW A;  4GP8 A;  5B3S A;  3BVD A;  4GP4 A;  3WFC B;  3S3B A;  3S8F A;  4G71 A;  3AG3 A;  1V55 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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