3AG3A

Bovine heart cytochrome c oxidase in the nitric oxide-bound fully reduced state at 100 k
Total Genus 208
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
208
sequence length
513
structure length
513
Chain Sequence
FINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Bovine cytochrome c oxidase structures enable O2 reduction with minimization of reactive oxygens and provide a proton-pumping gate
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Cytochrome c oxidase subunit 1
total genus 208
structure length 513
sequence length 513
chains with identical sequence N
ec nomenclature ec 1.9.3.1: Cytochrome-c oxidase.
pdb deposition date 2010-03-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00115 COX1 Cytochrome C and Quinol oxidase polypeptide I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase; Chain A Cytochrome c oxidase-like, subunit I domain 3ag3A00
3ASOA 4GP8A 3QJQA 1OCCA 4G70A 1QLEA 5B3SA 3AG1A 1OCOA 4G7SA 3DTUA 1XMEA 2EILA 3QJTA 5B1AA 3OM3A 2DYRA 1OCRA 2DYSA 3S3DA 3S8GA 2OCCA 2EIKA 2Y69A 3ABMA 3S3CA 3AG4A 5DJQA 3AYFA 3QJRA 4G7RA 3OMNA 5IY5A 3ASNA 3OMAA 3ABKA 2QPDA 1M56A 3WFBB 3S3BA 3WFDB 4G7QA 4GP4A 2EIMA 4G71A 3HB3A 3WFEB 2ZXWA 2GSMA 4FA7A 3X2QA 3OMIA 1FFTA 3QJSA 3AYGA 3MK7A 3FYIA 1EHKA 3O0RB 4G72A 3EH3A 3QJUA 3AG3A 3EH4A 2QPEA 2EINA 3S8FA 3AG2A 3EH5A 3FYEA 4N4YA 2YEVA 3BVDA 4FAAA 3EHBA 3QJVA 1OCZA 1V55A 5B1BA 2EIJA 4GP5A 3WG7A 1M57A 1V54A 3WFCB 1AR1A 3ABLA 4XYDA
chains in the Genus database with same CATH superfamily
3ASOA 4GP8A 3QJQA 1OCCA 4G70A 1QLEA 5B3SA 3AG1A 1OCOA 4G7SA 3DTUA 1XMEA 2EILA 3QJTA 5B1AA 3OM3A 2DYRA 1OCRA 2DYSA 3S3DA 3S8GA 2OCCA 2EIKA 2Y69A 3ABMA 3S3CA 3AG4A 5DJQA 3AYFA 3QJRA 4G7RA 3OMNA 5IY5A 3ASNA 3OMAA 3ABKA 2QPDA 1M56A 3WFBB 3S3BA 3WFDB 4G7QA 4GP4A 2EIMA 4G71A 3HB3A 3WFEB 2ZXWA 2GSMA 4FA7A 3X2QA 3OMIA 1FFTA 3QJSA 3AYGA 3MK7A 3FYIA 1EHKA 3O0RB 4G72A 3EH3A 3QJUA 3AG3A 3EH4A 2QPEA 2EINA 3S8FA 3AG2A 3EH5A 3FYEA 4N4YA 2YEVA 3BVDA 4FAAA 3EHBA 3QJVA 1OCZA 1V55A 5B1BA 2EIJA 4GP5A 3WG7A 1M57A 1V54A 3WFCB 1AR1A 3ABLA 4XYDA
chains in the Genus database with same CATH topology
3ASOA 4GP8A 3QJQA 1OCCA 4G70A 1QLEA 5B3SA 3AG1A 1OCOA 4G7SA 3DTUA 1XMEA 2EILA 3QJTA 5B1AA 3OM3A 2DYRA 1OCRA 2DYSA 3S3DA 3S8GA 2OCCA 2EIKA 2Y69A 3ABMA 3S3CA 3AG4A 5DJQA 3AYFA 3QJRA 4G7RA 3OMNA 5IY5A 3ASNA 3OMAA 3ABKA 2QPDA 1M56A 3WFBB 3S3BA 3WFDB 4G7QA 4GP4A 2EIMA 4G71A 3HB3A 3WFEB 2ZXWA 2GSMA 4FA7A 3X2QA 3OMIA 1FFTA 3QJSA 3AYGA 3MK7A 3FYIA 1EHKA 3O0RB 4G72A 3EH3A 3QJUA 3AG3A 3EH4A 2QPEA 2EINA 3S8FA 3AG2A 3EH5A 3FYEA 4N4YA 2YEVA 3BVDA 4FAAA 3EHBA 3QJVA 1OCZA 1V55A 5B1BA 2EIJA 4GP5A 3WG7A 1M57A 1V54A 3WFCB 1AR1A 3ABLA 4XYDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ASO A;  4GP8 A;  3QJQ A;  1OCC A;  4G70 A;  1QLE A;  5B3S A;  3AG1 A;  1OCO A;  4G7S A;  3DTU A;  1XME A;  2EIL A;  3QJT A;  5B1A A;  3OM3 A;  2DYR A;  1OCR A;  2DYS A;  3S3D A;  3S8G A;  2OCC A;  2EIK A;  2Y69 A;  3ABM A;  3S3C A;  3AG4 A;  5DJQ A;  3AYF A;  3QJR A;  4G7R A;  3OMN A;  5IY5 A;  3ASN A;  3OMA A;  3ABK A;  2QPD A;  1M56 A;  3WFB B;  3S3B A;  3WFD B;  4G7Q A;  4GP4 A;  2EIM A;  4G71 A;  3HB3 A;  3WFE B;  2ZXW A;  2GSM A;  4FA7 A;  3X2Q A;  3OMI A;  1FFT A;  3QJS A;  3AYG A;  3MK7 A;  3FYI A;  1EHK A;  3O0R B;  4G72 A;  3EH3 A;  3QJU A;  3AG3 A;  3EH4 A;  2QPE A;  2EIN A;  3S8F A;  3AG2 A;  3EH5 A;  3FYE A;  4N4Y A;  2YEV A;  3BVD A;  4FAA A;  3EHB A;  3QJV A;  1OCZ A;  1V55 A;  5B1B A;  2EIJ A;  4GP5 A;  3WG7 A;  1M57 A;  1V54 A;  3WFC B;  1AR1 A;  3ABL A;  4XYD A; 
#chains in the Genus database with same CATH topology
 3ASO A;  4GP8 A;  3QJQ A;  1OCC A;  4G70 A;  1QLE A;  5B3S A;  3AG1 A;  1OCO A;  4G7S A;  3DTU A;  1XME A;  2EIL A;  3QJT A;  5B1A A;  3OM3 A;  2DYR A;  1OCR A;  2DYS A;  3S3D A;  3S8G A;  2OCC A;  2EIK A;  2Y69 A;  3ABM A;  3S3C A;  3AG4 A;  5DJQ A;  3AYF A;  3QJR A;  4G7R A;  3OMN A;  5IY5 A;  3ASN A;  3OMA A;  3ABK A;  2QPD A;  1M56 A;  3WFB B;  3S3B A;  3WFD B;  4G7Q A;  4GP4 A;  2EIM A;  4G71 A;  3HB3 A;  3WFE B;  2ZXW A;  2GSM A;  4FA7 A;  3X2Q A;  3OMI A;  1FFT A;  3QJS A;  3AYG A;  3MK7 A;  3FYI A;  1EHK A;  3O0R B;  4G72 A;  3EH3 A;  3QJU A;  3AG3 A;  3EH4 A;  2QPE A;  2EIN A;  3S8F A;  3AG2 A;  3EH5 A;  3FYE A;  4N4Y A;  2YEV A;  3BVD A;  4FAA A;  3EHB A;  3QJV A;  1OCZ A;  1V55 A;  5B1B A;  2EIJ A;  4GP5 A;  3WG7 A;  1M57 A;  1V54 A;  3WFC B;  1AR1 A;  3ABL A;  4XYD A; 
#chains in the Genus database with same CATH homology
 3ASO A;  4GP8 A;  3QJQ A;  1OCC A;  4G70 A;  1QLE A;  5B3S A;  3AG1 A;  1OCO A;  4G7S A;  3DTU A;  1XME A;  2EIL A;  3QJT A;  5B1A A;  3OM3 A;  2DYR A;  1OCR A;  2DYS A;  3S3D A;  3S8G A;  2OCC A;  2EIK A;  2Y69 A;  3ABM A;  3S3C A;  3AG4 A;  5DJQ A;  3AYF A;  3QJR A;  4G7R A;  3OMN A;  5IY5 A;  3ASN A;  3OMA A;  3ABK A;  2QPD A;  1M56 A;  3WFB B;  3S3B A;  3WFD B;  4G7Q A;  4GP4 A;  2EIM A;  4G71 A;  3HB3 A;  3WFE B;  2ZXW A;  2GSM A;  4FA7 A;  3X2Q A;  3OMI A;  1FFT A;  3QJS A;  3AYG A;  3MK7 A;  3FYI A;  1EHK A;  3O0R B;  4G72 A;  3EH3 A;  3QJU A;  3AG3 A;  3EH4 A;  2QPE A;  2EIN A;  3S8F A;  3AG2 A;  3EH5 A;  3FYE A;  4N4Y A;  2YEV A;  3BVD A;  4FAA A;  3EHB A;  3QJV A;  1OCZ A;  1V55 A;  5B1B A;  2EIJ A;  4GP5 A;  3WG7 A;  1M57 A;  1V54 A;  3WFC B;  1AR1 A;  3ABL A;  4XYD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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