3AG3A

Bovine heart cytochrome c oxidase in the nitric oxide-bound fully reduced state at 100 k
Total Genus 208
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
208
sequence length
513
structure length
513
Chain Sequence
FINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Bovine cytochrome c oxidase structures enable O2 reduction with minimization of reactive oxygens and provide a proton-pumping gate
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Cytochrome c oxidase subunit 1
total genus 208
structure length 513
sequence length 513
chains with identical sequence N
ec nomenclature ec 1.9.3.1: Cytochrome-c oxidase.
pdb deposition date 2010-03-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00115 COX1 Cytochrome C and Quinol oxidase polypeptide I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase; Chain A Cytochrome c oxidase-like, subunit I domain 3ag3A00
4G7QA 3WFBB 3WFCB 1OCRA 3S3DA 3FYIA 3WG7A 3S8FA 3QJTA 3HB3A 3S3BA 2EINA 2EIJA 1OCOA 1XMEA 3QJUA 4G70A 3AG3A 3ASNA 3WFDB 4G72A 2DYSA 3EH3A 2GSMA 3AG2A 3S3CA 3ABKA 3O0RB 3ABMA 3OMIA 3QJVA 4GP5A 1V54A 1M56A 5DJQA 4G71A 4N4YA 3QJSA 3DTUA 3QJQA 2OCCA 1FFTA 3ABLA 3AYFA 2EILA 3X2QA 1OCZA 3OMNA 3AYGA 3EH4A 4FAAA 4FA7A 1QLEA 2YEVA 1AR1A 3OMAA 5B3SA 3AG4A 2EIKA 1V55A 3BVDA 2ZXWA 3EHBA 3ASOA 3FYEA 2QPDA 5B1BA 4XYDA 1M57A 3OM3A 4G7SA 2EIMA 2QPEA 3AG1A 3S8GA 5IY5A 2DYRA 3WFEB 5B1AA 4G7RA 3EH5A 1OCCA 4GP4A 1EHKA 3MK7A 4GP8A 3QJRA 2Y69A
chains in the Genus database with same CATH superfamily
4G7QA 3WFBB 3WFCB 1OCRA 3S3DA 3FYIA 3WG7A 3S8FA 3QJTA 3HB3A 3S3BA 2EINA 2EIJA 1OCOA 1XMEA 3QJUA 4G70A 3AG3A 3ASNA 3WFDB 4G72A 2DYSA 3EH3A 2GSMA 3AG2A 3S3CA 3ABKA 3O0RB 3ABMA 3OMIA 3QJVA 4GP5A 1V54A 1M56A 5DJQA 4G71A 4N4YA 3QJSA 3DTUA 3QJQA 2OCCA 1FFTA 3ABLA 3AYFA 2EILA 3X2QA 1OCZA 3OMNA 3AYGA 3EH4A 4FAAA 4FA7A 1QLEA 2YEVA 1AR1A 3OMAA 5B3SA 3AG4A 2EIKA 1V55A 3BVDA 2ZXWA 3EHBA 3ASOA 3FYEA 2QPDA 5B1BA 4XYDA 1M57A 3OM3A 4G7SA 2EIMA 2QPEA 3AG1A 3S8GA 5IY5A 2DYRA 3WFEB 5B1AA 4G7RA 3EH5A 1OCCA 4GP4A 1EHKA 3MK7A 4GP8A 3QJRA 2Y69A
chains in the Genus database with same CATH topology
4G7QA 3WFBB 3WFCB 1OCRA 3S3DA 3FYIA 3WG7A 3S8FA 3QJTA 3HB3A 3S3BA 2EINA 2EIJA 1OCOA 1XMEA 3QJUA 4G70A 3AG3A 3ASNA 3WFDB 4G72A 2DYSA 3EH3A 2GSMA 3AG2A 3S3CA 3ABKA 3O0RB 3ABMA 3OMIA 3QJVA 4GP5A 1V54A 1M56A 5DJQA 4G71A 4N4YA 3QJSA 3DTUA 3QJQA 2OCCA 1FFTA 3ABLA 3AYFA 2EILA 3X2QA 1OCZA 3OMNA 3AYGA 3EH4A 4FAAA 4FA7A 1QLEA 2YEVA 1AR1A 3OMAA 5B3SA 3AG4A 2EIKA 1V55A 3BVDA 2ZXWA 3EHBA 3ASOA 3FYEA 2QPDA 5B1BA 4XYDA 1M57A 3OM3A 4G7SA 2EIMA 2QPEA 3AG1A 3S8GA 5IY5A 2DYRA 3WFEB 5B1AA 4G7RA 3EH5A 1OCCA 4GP4A 1EHKA 3MK7A 4GP8A 3QJRA 2Y69A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4G7Q A;  3WFB B;  3WFC B;  1OCR A;  3S3D A;  3FYI A;  3WG7 A;  3S8F A;  3QJT A;  3HB3 A;  3S3B A;  2EIN A;  2EIJ A;  1OCO A;  1XME A;  3QJU A;  4G70 A;  3AG3 A;  3ASN A;  3WFD B;  4G72 A;  2DYS A;  3EH3 A;  2GSM A;  3AG2 A;  3S3C A;  3ABK A;  3O0R B;  3ABM A;  3OMI A;  3QJV A;  4GP5 A;  1V54 A;  1M56 A;  5DJQ A;  4G71 A;  4N4Y A;  3QJS A;  3DTU A;  3QJQ A;  2OCC A;  1FFT A;  3ABL A;  3AYF A;  2EIL A;  3X2Q A;  1OCZ A;  3OMN A;  3AYG A;  3EH4 A;  4FAA A;  4FA7 A;  1QLE A;  2YEV A;  1AR1 A;  3OMA A;  5B3S A;  3AG4 A;  2EIK A;  1V55 A;  3BVD A;  2ZXW A;  3EHB A;  3ASO A;  3FYE A;  2QPD A;  5B1B A;  4XYD A;  1M57 A;  3OM3 A;  4G7S A;  2EIM A;  2QPE A;  3AG1 A;  3S8G A;  5IY5 A;  2DYR A;  3WFE B;  5B1A A;  4G7R A;  3EH5 A;  1OCC A;  4GP4 A;  1EHK A;  3MK7 A;  4GP8 A;  3QJR A;  2Y69 A; 
#chains in the Genus database with same CATH topology
 4G7Q A;  3WFB B;  3WFC B;  1OCR A;  3S3D A;  3FYI A;  3WG7 A;  3S8F A;  3QJT A;  3HB3 A;  3S3B A;  2EIN A;  2EIJ A;  1OCO A;  1XME A;  3QJU A;  4G70 A;  3AG3 A;  3ASN A;  3WFD B;  4G72 A;  2DYS A;  3EH3 A;  2GSM A;  3AG2 A;  3S3C A;  3ABK A;  3O0R B;  3ABM A;  3OMI A;  3QJV A;  4GP5 A;  1V54 A;  1M56 A;  5DJQ A;  4G71 A;  4N4Y A;  3QJS A;  3DTU A;  3QJQ A;  2OCC A;  1FFT A;  3ABL A;  3AYF A;  2EIL A;  3X2Q A;  1OCZ A;  3OMN A;  3AYG A;  3EH4 A;  4FAA A;  4FA7 A;  1QLE A;  2YEV A;  1AR1 A;  3OMA A;  5B3S A;  3AG4 A;  2EIK A;  1V55 A;  3BVD A;  2ZXW A;  3EHB A;  3ASO A;  3FYE A;  2QPD A;  5B1B A;  4XYD A;  1M57 A;  3OM3 A;  4G7S A;  2EIM A;  2QPE A;  3AG1 A;  3S8G A;  5IY5 A;  2DYR A;  3WFE B;  5B1A A;  4G7R A;  3EH5 A;  1OCC A;  4GP4 A;  1EHK A;  3MK7 A;  4GP8 A;  3QJR A;  2Y69 A; 
#chains in the Genus database with same CATH homology
 4G7Q A;  3WFB B;  3WFC B;  1OCR A;  3S3D A;  3FYI A;  3WG7 A;  3S8F A;  3QJT A;  3HB3 A;  3S3B A;  2EIN A;  2EIJ A;  1OCO A;  1XME A;  3QJU A;  4G70 A;  3AG3 A;  3ASN A;  3WFD B;  4G72 A;  2DYS A;  3EH3 A;  2GSM A;  3AG2 A;  3S3C A;  3ABK A;  3O0R B;  3ABM A;  3OMI A;  3QJV A;  4GP5 A;  1V54 A;  1M56 A;  5DJQ A;  4G71 A;  4N4Y A;  3QJS A;  3DTU A;  3QJQ A;  2OCC A;  1FFT A;  3ABL A;  3AYF A;  2EIL A;  3X2Q A;  1OCZ A;  3OMN A;  3AYG A;  3EH4 A;  4FAA A;  4FA7 A;  1QLE A;  2YEV A;  1AR1 A;  3OMA A;  5B3S A;  3AG4 A;  2EIK A;  1V55 A;  3BVD A;  2ZXW A;  3EHB A;  3ASO A;  3FYE A;  2QPD A;  5B1B A;  4XYD A;  1M57 A;  3OM3 A;  4G7S A;  2EIM A;  2QPE A;  3AG1 A;  3S8G A;  5IY5 A;  2DYR A;  3WFE B;  5B1A A;  4G7R A;  3EH5 A;  1OCC A;  4GP4 A;  1EHK A;  3MK7 A;  4GP8 A;  3QJR A;  2Y69 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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