3AG4A

Bovine heart cytochrome c oxidase in the cyanide ion-bound fully reduced state at 100 k
Total Genus 208
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
208
sequence length
513
structure length
513
Chain Sequence
FINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Bovine cytochrome c oxidase structures enable O2 reduction with minimization of reactive oxygens and provide a proton-pumping gate
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Cytochrome c oxidase subunit 1
total genus 208
structure length 513
sequence length 513
chains with identical sequence N
ec nomenclature ec 1.9.3.1: Cytochrome-c oxidase.
pdb deposition date 2010-03-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00115 COX1 Cytochrome C and Quinol oxidase polypeptide I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase; Chain A Cytochrome c oxidase-like, subunit I domain 3ag4A00
2DYRA 2ZXWA 2YEVA 3S3BA 3WFDB 3OMNA 2EINA 3QJSA 5B1AA 3QJVA 1FFTA 4N4YA 3S3CA 3QJTA 3AYFA 1EHKA 4G71A 3AG3A 3ABKA 4GP4A 1V55A 5B1BA 3WFBB 3MK7A 4GP5A 1XMEA 4XYDA 5DJQA 2EIMA 2QPEA 3AYGA 3HB3A 4GP8A 3S3DA 2EILA 3ASOA 3O0RB 3OM3A 3AG2A 3WG7A 3FYEA 3QJRA 3EH4A 5B3SA 1M56A 1OCCA 3ABLA 3OMAA 3EHBA 3QJUA 1OCOA 1M57A 3EH3A 3S8GA 3ABMA 3EH5A 3WFCB 1QLEA 3ASNA 3BVDA 2OCCA 4FA7A 4G72A 3QJQA 3AG4A 4G7SA 4G7RA 1OCZA 2GSMA 1V54A 4G7QA 3WFEB 3DTUA 4FAAA 2Y69A 3OMIA 3S8FA 2QPDA 3X2QA 1AR1A 3FYIA 2DYSA 3AG1A 2EIKA 5IY5A 2EIJA 1OCRA 4G70A
chains in the Genus database with same CATH superfamily
2DYRA 2ZXWA 2YEVA 3S3BA 3WFDB 3OMNA 2EINA 3QJSA 5B1AA 3QJVA 1FFTA 4N4YA 3S3CA 3QJTA 3AYFA 1EHKA 4G71A 3AG3A 3ABKA 4GP4A 1V55A 5B1BA 3WFBB 3MK7A 4GP5A 1XMEA 4XYDA 5DJQA 2EIMA 2QPEA 3AYGA 3HB3A 4GP8A 3S3DA 2EILA 3ASOA 3O0RB 3OM3A 3AG2A 3WG7A 3FYEA 3QJRA 3EH4A 5B3SA 1M56A 1OCCA 3ABLA 3OMAA 3EHBA 3QJUA 1OCOA 1M57A 3EH3A 3S8GA 3ABMA 3EH5A 3WFCB 1QLEA 3ASNA 3BVDA 2OCCA 4FA7A 4G72A 3QJQA 3AG4A 4G7SA 4G7RA 1OCZA 2GSMA 1V54A 4G7QA 3WFEB 3DTUA 4FAAA 2Y69A 3OMIA 3S8FA 2QPDA 3X2QA 1AR1A 3FYIA 2DYSA 3AG1A 2EIKA 5IY5A 2EIJA 1OCRA 4G70A
chains in the Genus database with same CATH topology
2DYRA 2ZXWA 2YEVA 3S3BA 3WFDB 3OMNA 2EINA 3QJSA 5B1AA 3QJVA 1FFTA 4N4YA 3S3CA 3QJTA 3AYFA 1EHKA 4G71A 3AG3A 3ABKA 4GP4A 1V55A 5B1BA 3WFBB 3MK7A 4GP5A 1XMEA 4XYDA 5DJQA 2EIMA 2QPEA 3AYGA 3HB3A 4GP8A 3S3DA 2EILA 3ASOA 3O0RB 3OM3A 3AG2A 3WG7A 3FYEA 3QJRA 3EH4A 5B3SA 1M56A 1OCCA 3ABLA 3OMAA 3EHBA 3QJUA 1OCOA 1M57A 3EH3A 3S8GA 3ABMA 3EH5A 3WFCB 1QLEA 3ASNA 3BVDA 2OCCA 4FA7A 4G72A 3QJQA 3AG4A 4G7SA 4G7RA 1OCZA 2GSMA 1V54A 4G7QA 3WFEB 3DTUA 4FAAA 2Y69A 3OMIA 3S8FA 2QPDA 3X2QA 1AR1A 3FYIA 2DYSA 3AG1A 2EIKA 5IY5A 2EIJA 1OCRA 4G70A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DYR A;  2ZXW A;  2YEV A;  3S3B A;  3WFD B;  3OMN A;  2EIN A;  3QJS A;  5B1A A;  3QJV A;  1FFT A;  4N4Y A;  3S3C A;  3QJT A;  3AYF A;  1EHK A;  4G71 A;  3AG3 A;  3ABK A;  4GP4 A;  1V55 A;  5B1B A;  3WFB B;  3MK7 A;  4GP5 A;  1XME A;  4XYD A;  5DJQ A;  2EIM A;  2QPE A;  3AYG A;  3HB3 A;  4GP8 A;  3S3D A;  2EIL A;  3ASO A;  3O0R B;  3OM3 A;  3AG2 A;  3WG7 A;  3FYE A;  3QJR A;  3EH4 A;  5B3S A;  1M56 A;  1OCC A;  3ABL A;  3OMA A;  3EHB A;  3QJU A;  1OCO A;  1M57 A;  3EH3 A;  3S8G A;  3ABM A;  3EH5 A;  3WFC B;  1QLE A;  3ASN A;  3BVD A;  2OCC A;  4FA7 A;  4G72 A;  3QJQ A;  3AG4 A;  4G7S A;  4G7R A;  1OCZ A;  2GSM A;  1V54 A;  4G7Q A;  3WFE B;  3DTU A;  4FAA A;  2Y69 A;  3OMI A;  3S8F A;  2QPD A;  3X2Q A;  1AR1 A;  3FYI A;  2DYS A;  3AG1 A;  2EIK A;  5IY5 A;  2EIJ A;  1OCR A;  4G70 A; 
#chains in the Genus database with same CATH topology
 2DYR A;  2ZXW A;  2YEV A;  3S3B A;  3WFD B;  3OMN A;  2EIN A;  3QJS A;  5B1A A;  3QJV A;  1FFT A;  4N4Y A;  3S3C A;  3QJT A;  3AYF A;  1EHK A;  4G71 A;  3AG3 A;  3ABK A;  4GP4 A;  1V55 A;  5B1B A;  3WFB B;  3MK7 A;  4GP5 A;  1XME A;  4XYD A;  5DJQ A;  2EIM A;  2QPE A;  3AYG A;  3HB3 A;  4GP8 A;  3S3D A;  2EIL A;  3ASO A;  3O0R B;  3OM3 A;  3AG2 A;  3WG7 A;  3FYE A;  3QJR A;  3EH4 A;  5B3S A;  1M56 A;  1OCC A;  3ABL A;  3OMA A;  3EHB A;  3QJU A;  1OCO A;  1M57 A;  3EH3 A;  3S8G A;  3ABM A;  3EH5 A;  3WFC B;  1QLE A;  3ASN A;  3BVD A;  2OCC A;  4FA7 A;  4G72 A;  3QJQ A;  3AG4 A;  4G7S A;  4G7R A;  1OCZ A;  2GSM A;  1V54 A;  4G7Q A;  3WFE B;  3DTU A;  4FAA A;  2Y69 A;  3OMI A;  3S8F A;  2QPD A;  3X2Q A;  1AR1 A;  3FYI A;  2DYS A;  3AG1 A;  2EIK A;  5IY5 A;  2EIJ A;  1OCR A;  4G70 A; 
#chains in the Genus database with same CATH homology
 2DYR A;  2ZXW A;  2YEV A;  3S3B A;  3WFD B;  3OMN A;  2EIN A;  3QJS A;  5B1A A;  3QJV A;  1FFT A;  4N4Y A;  3S3C A;  3QJT A;  3AYF A;  1EHK A;  4G71 A;  3AG3 A;  3ABK A;  4GP4 A;  1V55 A;  5B1B A;  3WFB B;  3MK7 A;  4GP5 A;  1XME A;  4XYD A;  5DJQ A;  2EIM A;  2QPE A;  3AYG A;  3HB3 A;  4GP8 A;  3S3D A;  2EIL A;  3ASO A;  3O0R B;  3OM3 A;  3AG2 A;  3WG7 A;  3FYE A;  3QJR A;  3EH4 A;  5B3S A;  1M56 A;  1OCC A;  3ABL A;  3OMA A;  3EHB A;  3QJU A;  1OCO A;  1M57 A;  3EH3 A;  3S8G A;  3ABM A;  3EH5 A;  3WFC B;  1QLE A;  3ASN A;  3BVD A;  2OCC A;  4FA7 A;  4G72 A;  3QJQ A;  3AG4 A;  4G7S A;  4G7R A;  1OCZ A;  2GSM A;  1V54 A;  4G7Q A;  3WFE B;  3DTU A;  4FAA A;  2Y69 A;  3OMI A;  3S8F A;  2QPD A;  3X2Q A;  1AR1 A;  3FYI A;  2DYS A;  3AG1 A;  2EIK A;  5IY5 A;  2EIJ A;  1OCR A;  4G70 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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