3EHBA

A d-pathway mutation decouples the paracoccus denitrificans cytochrome c oxidase by altering the side chain orientation of a distant, conserved glutamate
Total Genus 221
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
221
sequence length
529
structure length
529
Chain Sequence
GFFTRWFMSTNHKDIGILYLFTAGIVGLISVCFTVYMRMELQHPGVQYMCLEGARLIADASAECTPNGHLWNVMITYHGVLMMFFVVIPALFGGFGNYFMPLHIGAPDMAFPRLDNLSYWMYVCGVALGVASLLAPGGNDQMGSGVGWVLYPPLSTTEAGYSMDLAIFAVHVSGASSILGAINIITTFLNMRAPGMTLFKVPLFAWSVFITAWLILLSLPVLAGAITMLLMDRNFGTQFFDPAGGGDPVLYQHILWFFGHPEVYIIILPGFGIISHVISTFAKKPIFGYLPMVLAMAAIGILGFVVWAHHMYTAGMSLTQQAYFMLATMTIAVPTGIKVFSWIATMWGGSIEFKTPMLWAFGFLFLFTVGGVTGVVLSQAPLDRVYHDTYYVVAHFHYVMSLGAVFGIFAGVYYWIGKMSGRQYPEWAGQLHFWMMFIGSNLIFFPQHFLGRQGMPRRYIDYPVEFAYWNNISSIGAYISFASFLFFIGIVFYTLFAGKRVNVPNYWNEHADTLEWTLPSPPPEHTFET
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A d-pathway mutation decouples the paracoccusdenitrificans cytochrome C oxidase by altering the side-chain orientation of a distant conserved glutamate
pubmed doi rcsb
molecule tags Oxidoreductase/immune system
source organism Paracoccus denitrificans
molecule keywords Cytochrome c oxidase subunit 1-beta
total genus 221
structure length 529
sequence length 529
ec nomenclature ec 1.9.3.1: Cytochrome-c oxidase.
pdb deposition date 2008-09-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00115 COX1 Cytochrome C and Quinol oxidase polypeptide I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase; Chain A Cytochrome c oxidase-like, subunit I domain 3ehbA00
3OMIA 3AG4A 2EIKA 5B1AA 2QPEA 4FAAA 3FYEA 2EINA 3S8GA 3AYFA 1V54A 3WFCB 2OCCA 4GP5A 1QLEA 4G7QA 3ABKA 3OMAA 4N4YA 5IY5A 3EH4A 4G70A 3S8FA 2EIJA 1V55A 3BVDA 1OCZA 5B1BA 3WG7A 3QJSA 3MK7A 3S3DA 3S3BA 3AG2A 3WFDB 3QJUA 3HB3A 4GP8A 4G72A 1EHKA 3FYIA 3QJVA 3EH5A 3AG1A 4G7SA 3X2QA 2YEVA 3WFEB 3DTUA 2QPDA 3QJTA 3O0RB 3WFBB 3S3CA 1OCCA 2ZXWA 3AG3A 4XYDA 3OMNA 3ASNA 5B3SA 3EHBA 1M57A 2GSMA 2DYSA 4G71A 3ABMA 3AYGA 2Y69A 4FA7A 1AR1A 3OM3A 3EH3A 2DYRA 5DJQA 1FFTA 4G7RA 1M56A 2EILA 1XMEA 3QJQA 3ASOA 4GP4A 1OCOA 3ABLA 1OCRA 2EIMA 3QJRA
chains in the Genus database with same CATH superfamily
3OMIA 3AG4A 2EIKA 5B1AA 2QPEA 4FAAA 3FYEA 2EINA 3S8GA 3AYFA 1V54A 3WFCB 2OCCA 4GP5A 1QLEA 4G7QA 3ABKA 3OMAA 4N4YA 5IY5A 3EH4A 4G70A 3S8FA 2EIJA 1V55A 3BVDA 1OCZA 5B1BA 3WG7A 3QJSA 3MK7A 3S3DA 3S3BA 3AG2A 3WFDB 3QJUA 3HB3A 4GP8A 4G72A 1EHKA 3FYIA 3QJVA 3EH5A 3AG1A 4G7SA 3X2QA 2YEVA 3WFEB 3DTUA 2QPDA 3QJTA 3O0RB 3WFBB 3S3CA 1OCCA 2ZXWA 3AG3A 4XYDA 3OMNA 3ASNA 5B3SA 3EHBA 1M57A 2GSMA 2DYSA 4G71A 3ABMA 3AYGA 2Y69A 4FA7A 1AR1A 3OM3A 3EH3A 2DYRA 5DJQA 1FFTA 4G7RA 1M56A 2EILA 1XMEA 3QJQA 3ASOA 4GP4A 1OCOA 3ABLA 1OCRA 2EIMA 3QJRA
chains in the Genus database with same CATH topology
3OMIA 3AG4A 2EIKA 5B1AA 2QPEA 4FAAA 3FYEA 2EINA 3S8GA 3AYFA 1V54A 3WFCB 2OCCA 4GP5A 1QLEA 4G7QA 3ABKA 3OMAA 4N4YA 5IY5A 3EH4A 4G70A 3S8FA 2EIJA 1V55A 3BVDA 1OCZA 5B1BA 3WG7A 3QJSA 3MK7A 3S3DA 3S3BA 3AG2A 3WFDB 3QJUA 3HB3A 4GP8A 4G72A 1EHKA 3FYIA 3QJVA 3EH5A 3AG1A 4G7SA 3X2QA 2YEVA 3WFEB 3DTUA 2QPDA 3QJTA 3O0RB 3WFBB 3S3CA 1OCCA 2ZXWA 3AG3A 4XYDA 3OMNA 3ASNA 5B3SA 3EHBA 1M57A 2GSMA 2DYSA 4G71A 3ABMA 3AYGA 2Y69A 4FA7A 1AR1A 3OM3A 3EH3A 2DYRA 5DJQA 1FFTA 4G7RA 1M56A 2EILA 1XMEA 3QJQA 3ASOA 4GP4A 1OCOA 3ABLA 1OCRA 2EIMA 3QJRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OMI A;  3AG4 A;  2EIK A;  5B1A A;  2QPE A;  4FAA A;  3FYE A;  2EIN A;  3S8G A;  3AYF A;  1V54 A;  3WFC B;  2OCC A;  4GP5 A;  1QLE A;  4G7Q A;  3ABK A;  3OMA A;  4N4Y A;  5IY5 A;  3EH4 A;  4G70 A;  3S8F A;  2EIJ A;  1V55 A;  3BVD A;  1OCZ A;  5B1B A;  3WG7 A;  3QJS A;  3MK7 A;  3S3D A;  3S3B A;  3AG2 A;  3WFD B;  3QJU A;  3HB3 A;  4GP8 A;  4G72 A;  1EHK A;  3FYI A;  3QJV A;  3EH5 A;  3AG1 A;  4G7S A;  3X2Q A;  2YEV A;  3WFE B;  3DTU A;  2QPD A;  3QJT A;  3O0R B;  3WFB B;  3S3C A;  1OCC A;  2ZXW A;  3AG3 A;  4XYD A;  3OMN A;  3ASN A;  5B3S A;  3EHB A;  1M57 A;  2GSM A;  2DYS A;  4G71 A;  3ABM A;  3AYG A;  2Y69 A;  4FA7 A;  1AR1 A;  3OM3 A;  3EH3 A;  2DYR A;  5DJQ A;  1FFT A;  4G7R A;  1M56 A;  2EIL A;  1XME A;  3QJQ A;  3ASO A;  4GP4 A;  1OCO A;  3ABL A;  1OCR A;  2EIM A;  3QJR A; 
#chains in the Genus database with same CATH topology
 3OMI A;  3AG4 A;  2EIK A;  5B1A A;  2QPE A;  4FAA A;  3FYE A;  2EIN A;  3S8G A;  3AYF A;  1V54 A;  3WFC B;  2OCC A;  4GP5 A;  1QLE A;  4G7Q A;  3ABK A;  3OMA A;  4N4Y A;  5IY5 A;  3EH4 A;  4G70 A;  3S8F A;  2EIJ A;  1V55 A;  3BVD A;  1OCZ A;  5B1B A;  3WG7 A;  3QJS A;  3MK7 A;  3S3D A;  3S3B A;  3AG2 A;  3WFD B;  3QJU A;  3HB3 A;  4GP8 A;  4G72 A;  1EHK A;  3FYI A;  3QJV A;  3EH5 A;  3AG1 A;  4G7S A;  3X2Q A;  2YEV A;  3WFE B;  3DTU A;  2QPD A;  3QJT A;  3O0R B;  3WFB B;  3S3C A;  1OCC A;  2ZXW A;  3AG3 A;  4XYD A;  3OMN A;  3ASN A;  5B3S A;  3EHB A;  1M57 A;  2GSM A;  2DYS A;  4G71 A;  3ABM A;  3AYG A;  2Y69 A;  4FA7 A;  1AR1 A;  3OM3 A;  3EH3 A;  2DYR A;  5DJQ A;  1FFT A;  4G7R A;  1M56 A;  2EIL A;  1XME A;  3QJQ A;  3ASO A;  4GP4 A;  1OCO A;  3ABL A;  1OCR A;  2EIM A;  3QJR A; 
#chains in the Genus database with same CATH homology
 3OMI A;  3AG4 A;  2EIK A;  5B1A A;  2QPE A;  4FAA A;  3FYE A;  2EIN A;  3S8G A;  3AYF A;  1V54 A;  3WFC B;  2OCC A;  4GP5 A;  1QLE A;  4G7Q A;  3ABK A;  3OMA A;  4N4Y A;  5IY5 A;  3EH4 A;  4G70 A;  3S8F A;  2EIJ A;  1V55 A;  3BVD A;  1OCZ A;  5B1B A;  3WG7 A;  3QJS A;  3MK7 A;  3S3D A;  3S3B A;  3AG2 A;  3WFD B;  3QJU A;  3HB3 A;  4GP8 A;  4G72 A;  1EHK A;  3FYI A;  3QJV A;  3EH5 A;  3AG1 A;  4G7S A;  3X2Q A;  2YEV A;  3WFE B;  3DTU A;  2QPD A;  3QJT A;  3O0R B;  3WFB B;  3S3C A;  1OCC A;  2ZXW A;  3AG3 A;  4XYD A;  3OMN A;  3ASN A;  5B3S A;  3EHB A;  1M57 A;  2GSM A;  2DYS A;  4G71 A;  3ABM A;  3AYG A;  2Y69 A;  4FA7 A;  1AR1 A;  3OM3 A;  3EH3 A;  2DYR A;  5DJQ A;  1FFT A;  4G7R A;  1M56 A;  2EIL A;  1XME A;  3QJQ A;  3ASO A;  4GP4 A;  1OCO A;  3ABL A;  1OCR A;  2EIM A;  3QJR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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