3FYEA

Catalytic core subunits (i and ii) of cytochrome c oxidase from rhodobacter sphaeroides in the reduced state
Total Genus 228
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
228
sequence length
535
structure length
535
Chain Sequence
FTRWFMSTNHKDIGVLYLFTGGLVGLISVAFTVYMRMELMAPGVQFMCAEHLESGLVKGFFQSLWPSAVENCTPNGHLWNVMITGHGILMMFFVVIPALFGGFGNYFMPLHIGAPDMAFPRMNNLSYWLYVAGTSLAVASLFAPGGNGQLGSGIGWVLYPPLSTSESGYSTDLAIFAVHLSGASSILGAINMITTFLNMRAPGMTMHKVPLFAWSIFVTAWLILLALPVLAGAITMLLTDRNFGTTFFQPSGGGDPVLYQHILWFFGHPEVYIIVLPAFGIVSHVIATFAKKPIFGYLPMVYAMVAIGVLGFVVWAHHMYTAGLSLTQQSYFMMATMVIAVPTGIKIFSWIATMWGGSIELKTPMLWALGFLFLFTVGGVTGIVLSQASVDRYYHDTYYVVAHFHYVMSLGAVFGIFAGIYFWIGKMSGRQYPEWAGKLHFWMMFVGANLTFFPQHFLGRQGMPRRYIDYPEAFATWNFVSSLGAFLSFASFLFFLGVIFYTLTRGARVTANNYWNEHADTLEWTLTSPPPEHTF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Redox dependent conformational changes in cytochrome c oxidase suggest a gating mechanism for proton uptake.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Rhodobacter sphaeroides
molecule keywords Cytochrome C oxidase subunit 1
total genus 228
structure length 535
sequence length 535
chains with identical sequence C
ec nomenclature ec 1.9.3.1: Cytochrome-c oxidase.
pdb deposition date 2009-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00115 COX1 Cytochrome C and Quinol oxidase polypeptide I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase; Chain A Cytochrome c oxidase-like, subunit I domain 3fyeA00
3BVDA 4G7SA 3S8GA 2OCCA 5B1BA 3AG4A 5IY5A 4G7QA 2DYRA 1QLEA 2EIKA 1M56A 2Y69A 1M57A 3MK7A 4G71A 3AG1A 4N4YA 3AG3A 5B1AA 3AG2A 2GSMA 1OCZA 3OMAA 3QJUA 5DJQA 2EIMA 2ZXWA 3QJSA 4GP4A 3S3BA 3DTUA 3WFBB 3OM3A 2EINA 3WFEB 1EHKA 3AYGA 3QJQA 3QJRA 2QPDA 3EH4A 4GP8A 2DYSA 2YEVA 3EH3A 3OMIA 3QJTA 5B3SA 1OCOA 3HB3A 4G7RA 3S8FA 3OMNA 1XMEA 3WG7A 1OCCA 3ASOA 3S3CA 4FAAA 1OCRA 3EH5A 4XYDA 3X2QA 3FYIA 1V54A 3WFCB 3FYEA 4GP5A 1AR1A 3AYFA 4G70A 4G72A 3O0RB 2EIJA 3S3DA 3QJVA 1V55A 3EHBA 3ABMA 3ASNA 2EILA 3ABKA 3WFDB 1FFTA 3ABLA 2QPEA 4FA7A
chains in the Genus database with same CATH superfamily
3BVDA 4G7SA 3S8GA 2OCCA 5B1BA 3AG4A 5IY5A 4G7QA 2DYRA 1QLEA 2EIKA 1M56A 2Y69A 1M57A 3MK7A 4G71A 3AG1A 4N4YA 3AG3A 5B1AA 3AG2A 2GSMA 1OCZA 3OMAA 3QJUA 5DJQA 2EIMA 2ZXWA 3QJSA 4GP4A 3S3BA 3DTUA 3WFBB 3OM3A 2EINA 3WFEB 1EHKA 3AYGA 3QJQA 3QJRA 2QPDA 3EH4A 4GP8A 2DYSA 2YEVA 3EH3A 3OMIA 3QJTA 5B3SA 1OCOA 3HB3A 4G7RA 3S8FA 3OMNA 1XMEA 3WG7A 1OCCA 3ASOA 3S3CA 4FAAA 1OCRA 3EH5A 4XYDA 3X2QA 3FYIA 1V54A 3WFCB 3FYEA 4GP5A 1AR1A 3AYFA 4G70A 4G72A 3O0RB 2EIJA 3S3DA 3QJVA 1V55A 3EHBA 3ABMA 3ASNA 2EILA 3ABKA 3WFDB 1FFTA 3ABLA 2QPEA 4FA7A
chains in the Genus database with same CATH topology
3BVDA 4G7SA 3S8GA 2OCCA 5B1BA 3AG4A 5IY5A 4G7QA 2DYRA 1QLEA 2EIKA 1M56A 2Y69A 1M57A 3MK7A 4G71A 3AG1A 4N4YA 3AG3A 5B1AA 3AG2A 2GSMA 1OCZA 3OMAA 3QJUA 5DJQA 2EIMA 2ZXWA 3QJSA 4GP4A 3S3BA 3DTUA 3WFBB 3OM3A 2EINA 3WFEB 1EHKA 3AYGA 3QJQA 3QJRA 2QPDA 3EH4A 4GP8A 2DYSA 2YEVA 3EH3A 3OMIA 3QJTA 5B3SA 1OCOA 3HB3A 4G7RA 3S8FA 3OMNA 1XMEA 3WG7A 1OCCA 3ASOA 3S3CA 4FAAA 1OCRA 3EH5A 4XYDA 3X2QA 3FYIA 1V54A 3WFCB 3FYEA 4GP5A 1AR1A 3AYFA 4G70A 4G72A 3O0RB 2EIJA 3S3DA 3QJVA 1V55A 3EHBA 3ABMA 3ASNA 2EILA 3ABKA 3WFDB 1FFTA 3ABLA 2QPEA 4FA7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BVD A;  4G7S A;  3S8G A;  2OCC A;  5B1B A;  3AG4 A;  5IY5 A;  4G7Q A;  2DYR A;  1QLE A;  2EIK A;  1M56 A;  2Y69 A;  1M57 A;  3MK7 A;  4G71 A;  3AG1 A;  4N4Y A;  3AG3 A;  5B1A A;  3AG2 A;  2GSM A;  1OCZ A;  3OMA A;  3QJU A;  5DJQ A;  2EIM A;  2ZXW A;  3QJS A;  4GP4 A;  3S3B A;  3DTU A;  3WFB B;  3OM3 A;  2EIN A;  3WFE B;  1EHK A;  3AYG A;  3QJQ A;  3QJR A;  2QPD A;  3EH4 A;  4GP8 A;  2DYS A;  2YEV A;  3EH3 A;  3OMI A;  3QJT A;  5B3S A;  1OCO A;  3HB3 A;  4G7R A;  3S8F A;  3OMN A;  1XME A;  3WG7 A;  1OCC A;  3ASO A;  3S3C A;  4FAA A;  1OCR A;  3EH5 A;  4XYD A;  3X2Q A;  3FYI A;  1V54 A;  3WFC B;  3FYE A;  4GP5 A;  1AR1 A;  3AYF A;  4G70 A;  4G72 A;  3O0R B;  2EIJ A;  3S3D A;  3QJV A;  1V55 A;  3EHB A;  3ABM A;  3ASN A;  2EIL A;  3ABK A;  3WFD B;  1FFT A;  3ABL A;  2QPE A;  4FA7 A; 
#chains in the Genus database with same CATH topology
 3BVD A;  4G7S A;  3S8G A;  2OCC A;  5B1B A;  3AG4 A;  5IY5 A;  4G7Q A;  2DYR A;  1QLE A;  2EIK A;  1M56 A;  2Y69 A;  1M57 A;  3MK7 A;  4G71 A;  3AG1 A;  4N4Y A;  3AG3 A;  5B1A A;  3AG2 A;  2GSM A;  1OCZ A;  3OMA A;  3QJU A;  5DJQ A;  2EIM A;  2ZXW A;  3QJS A;  4GP4 A;  3S3B A;  3DTU A;  3WFB B;  3OM3 A;  2EIN A;  3WFE B;  1EHK A;  3AYG A;  3QJQ A;  3QJR A;  2QPD A;  3EH4 A;  4GP8 A;  2DYS A;  2YEV A;  3EH3 A;  3OMI A;  3QJT A;  5B3S A;  1OCO A;  3HB3 A;  4G7R A;  3S8F A;  3OMN A;  1XME A;  3WG7 A;  1OCC A;  3ASO A;  3S3C A;  4FAA A;  1OCR A;  3EH5 A;  4XYD A;  3X2Q A;  3FYI A;  1V54 A;  3WFC B;  3FYE A;  4GP5 A;  1AR1 A;  3AYF A;  4G70 A;  4G72 A;  3O0R B;  2EIJ A;  3S3D A;  3QJV A;  1V55 A;  3EHB A;  3ABM A;  3ASN A;  2EIL A;  3ABK A;  3WFD B;  1FFT A;  3ABL A;  2QPE A;  4FA7 A; 
#chains in the Genus database with same CATH homology
 3BVD A;  4G7S A;  3S8G A;  2OCC A;  5B1B A;  3AG4 A;  5IY5 A;  4G7Q A;  2DYR A;  1QLE A;  2EIK A;  1M56 A;  2Y69 A;  1M57 A;  3MK7 A;  4G71 A;  3AG1 A;  4N4Y A;  3AG3 A;  5B1A A;  3AG2 A;  2GSM A;  1OCZ A;  3OMA A;  3QJU A;  5DJQ A;  2EIM A;  2ZXW A;  3QJS A;  4GP4 A;  3S3B A;  3DTU A;  3WFB B;  3OM3 A;  2EIN A;  3WFE B;  1EHK A;  3AYG A;  3QJQ A;  3QJR A;  2QPD A;  3EH4 A;  4GP8 A;  2DYS A;  2YEV A;  3EH3 A;  3OMI A;  3QJT A;  5B3S A;  1OCO A;  3HB3 A;  4G7R A;  3S8F A;  3OMN A;  1XME A;  3WG7 A;  1OCC A;  3ASO A;  3S3C A;  4FAA A;  1OCR A;  3EH5 A;  4XYD A;  3X2Q A;  3FYI A;  1V54 A;  3WFC B;  3FYE A;  4GP5 A;  1AR1 A;  3AYF A;  4G70 A;  4G72 A;  3O0R B;  2EIJ A;  3S3D A;  3QJV A;  1V55 A;  3EHB A;  3ABM A;  3ASN A;  2EIL A;  3ABK A;  3WFD B;  1FFT A;  3ABL A;  2QPE A;  4FA7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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