3FYIA

Catalytic core subunits (i and ii) of cytochrome c oxidase from rhodobacter sphaeroides in the reduced state bound with cyanide
Total Genus 229
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
229
sequence length
535
structure length
535
Chain Sequence
FTRWFMSTNHKDIGVLYLFTGGLVGLISVAFTVYMRMELMAPGVQFMCAEHLESGLVKGFFQSLWPSAVENCTPNGHLWNVMITGHGILMMFFVVIPALFGGFGNYFMPLHIGAPDMAFPRMNNLSYWLYVAGTSLAVASLFAPGGNGQLGSGIGWVLYPPLSTSESGYSTDLAIFAVHLSGASSILGAINMITTFLNMRAPGMTMHKVPLFAWSIFVTAWLILLALPVLAGAITMLLTDRNFGTTFFQPSGGGDPVLYQHILWFFGHPEVYIIVLPAFGIVSHVIATFAKKPIFGYLPMVYAMVAIGVLGFVVWAHHMYTAGLSLTQQSYFMMATMVIAVPTGIKIFSWIATMWGGSIELKTPMLWALGFLFLFTVGGVTGIVLSQASVDRYYHDTYYVVAHFHYVMSLGAVFGIFAGIYFWIGKMSGRQYPEWAGKLHFWMMFVGANLTFFPQHFLGRQGMPRRYIDYPEAFATWNFVSSLGAFLSFASFLFFLGVIFYTLTRGARVTANNYWNEHADTLEWTLTSPPPEHTF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Redox dependent conformational changes in cytochrome c oxidase suggest a gating mechanism for proton uptake.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Rhodobacter sphaeroides
molecule keywords Cytochrome c oxidase subunit 1
total genus 229
structure length 535
sequence length 535
chains with identical sequence C
ec nomenclature ec 1.9.3.1: Cytochrome-c oxidase.
pdb deposition date 2009-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00115 COX1 Cytochrome C and Quinol oxidase polypeptide I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase; Chain A Cytochrome c oxidase-like, subunit I domain 3fyiA00
3OMNA 3ASNA 3ASOA 3WFEB 2DYSA 3OMAA 4G7SA 1QLEA 3AG1A 3WFBB 5B3SA 2EIJA 3O0RB 4FA7A 1V55A 3S3BA 3S3CA 1AR1A 3QJUA 1OCZA 1OCOA 2DYRA 3X2QA 3EH5A 3FYEA 2QPEA 3DTUA 3EHBA 4N4YA 2GSMA 2OCCA 4G7RA 3WG7A 1V54A 4GP5A 1EHKA 2EIMA 3MK7A 2EILA 3EH4A 4G7QA 3ABLA 4GP8A 3AYGA 3OMIA 3HB3A 5IY5A 2QPDA 2ZXWA 3S8FA 1OCRA 3ABMA 3AYFA 5B1BA 5DJQA 3S8GA 3OM3A 2YEVA 3QJVA 4G72A 3WFCB 3ABKA 3S3DA 4FAAA 3AG2A 4G71A 3EH3A 4XYDA 1OCCA 1XMEA 3QJSA 3AG4A 2Y69A 1FFTA 1M56A 3FYIA 4GP4A 3QJRA 1M57A 2EINA 3BVDA 3QJQA 5B1AA 2EIKA 4G70A 3QJTA 3WFDB 3AG3A
chains in the Genus database with same CATH superfamily
3OMNA 3ASNA 3ASOA 3WFEB 2DYSA 3OMAA 4G7SA 1QLEA 3AG1A 3WFBB 5B3SA 2EIJA 3O0RB 4FA7A 1V55A 3S3BA 3S3CA 1AR1A 3QJUA 1OCZA 1OCOA 2DYRA 3X2QA 3EH5A 3FYEA 2QPEA 3DTUA 3EHBA 4N4YA 2GSMA 2OCCA 4G7RA 3WG7A 1V54A 4GP5A 1EHKA 2EIMA 3MK7A 2EILA 3EH4A 4G7QA 3ABLA 4GP8A 3AYGA 3OMIA 3HB3A 5IY5A 2QPDA 2ZXWA 3S8FA 1OCRA 3ABMA 3AYFA 5B1BA 5DJQA 3S8GA 3OM3A 2YEVA 3QJVA 4G72A 3WFCB 3ABKA 3S3DA 4FAAA 3AG2A 4G71A 3EH3A 4XYDA 1OCCA 1XMEA 3QJSA 3AG4A 2Y69A 1FFTA 1M56A 3FYIA 4GP4A 3QJRA 1M57A 2EINA 3BVDA 3QJQA 5B1AA 2EIKA 4G70A 3QJTA 3WFDB 3AG3A
chains in the Genus database with same CATH topology
3OMNA 3ASNA 3ASOA 3WFEB 2DYSA 3OMAA 4G7SA 1QLEA 3AG1A 3WFBB 5B3SA 2EIJA 3O0RB 4FA7A 1V55A 3S3BA 3S3CA 1AR1A 3QJUA 1OCZA 1OCOA 2DYRA 3X2QA 3EH5A 3FYEA 2QPEA 3DTUA 3EHBA 4N4YA 2GSMA 2OCCA 4G7RA 3WG7A 1V54A 4GP5A 1EHKA 2EIMA 3MK7A 2EILA 3EH4A 4G7QA 3ABLA 4GP8A 3AYGA 3OMIA 3HB3A 5IY5A 2QPDA 2ZXWA 3S8FA 1OCRA 3ABMA 3AYFA 5B1BA 5DJQA 3S8GA 3OM3A 2YEVA 3QJVA 4G72A 3WFCB 3ABKA 3S3DA 4FAAA 3AG2A 4G71A 3EH3A 4XYDA 1OCCA 1XMEA 3QJSA 3AG4A 2Y69A 1FFTA 1M56A 3FYIA 4GP4A 3QJRA 1M57A 2EINA 3BVDA 3QJQA 5B1AA 2EIKA 4G70A 3QJTA 3WFDB 3AG3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OMN A;  3ASN A;  3ASO A;  3WFE B;  2DYS A;  3OMA A;  4G7S A;  1QLE A;  3AG1 A;  3WFB B;  5B3S A;  2EIJ A;  3O0R B;  4FA7 A;  1V55 A;  3S3B A;  3S3C A;  1AR1 A;  3QJU A;  1OCZ A;  1OCO A;  2DYR A;  3X2Q A;  3EH5 A;  3FYE A;  2QPE A;  3DTU A;  3EHB A;  4N4Y A;  2GSM A;  2OCC A;  4G7R A;  3WG7 A;  1V54 A;  4GP5 A;  1EHK A;  2EIM A;  3MK7 A;  2EIL A;  3EH4 A;  4G7Q A;  3ABL A;  4GP8 A;  3AYG A;  3OMI A;  3HB3 A;  5IY5 A;  2QPD A;  2ZXW A;  3S8F A;  1OCR A;  3ABM A;  3AYF A;  5B1B A;  5DJQ A;  3S8G A;  3OM3 A;  2YEV A;  3QJV A;  4G72 A;  3WFC B;  3ABK A;  3S3D A;  4FAA A;  3AG2 A;  4G71 A;  3EH3 A;  4XYD A;  1OCC A;  1XME A;  3QJS A;  3AG4 A;  2Y69 A;  1FFT A;  1M56 A;  3FYI A;  4GP4 A;  3QJR A;  1M57 A;  2EIN A;  3BVD A;  3QJQ A;  5B1A A;  2EIK A;  4G70 A;  3QJT A;  3WFD B;  3AG3 A; 
#chains in the Genus database with same CATH topology
 3OMN A;  3ASN A;  3ASO A;  3WFE B;  2DYS A;  3OMA A;  4G7S A;  1QLE A;  3AG1 A;  3WFB B;  5B3S A;  2EIJ A;  3O0R B;  4FA7 A;  1V55 A;  3S3B A;  3S3C A;  1AR1 A;  3QJU A;  1OCZ A;  1OCO A;  2DYR A;  3X2Q A;  3EH5 A;  3FYE A;  2QPE A;  3DTU A;  3EHB A;  4N4Y A;  2GSM A;  2OCC A;  4G7R A;  3WG7 A;  1V54 A;  4GP5 A;  1EHK A;  2EIM A;  3MK7 A;  2EIL A;  3EH4 A;  4G7Q A;  3ABL A;  4GP8 A;  3AYG A;  3OMI A;  3HB3 A;  5IY5 A;  2QPD A;  2ZXW A;  3S8F A;  1OCR A;  3ABM A;  3AYF A;  5B1B A;  5DJQ A;  3S8G A;  3OM3 A;  2YEV A;  3QJV A;  4G72 A;  3WFC B;  3ABK A;  3S3D A;  4FAA A;  3AG2 A;  4G71 A;  3EH3 A;  4XYD A;  1OCC A;  1XME A;  3QJS A;  3AG4 A;  2Y69 A;  1FFT A;  1M56 A;  3FYI A;  4GP4 A;  3QJR A;  1M57 A;  2EIN A;  3BVD A;  3QJQ A;  5B1A A;  2EIK A;  4G70 A;  3QJT A;  3WFD B;  3AG3 A; 
#chains in the Genus database with same CATH homology
 3OMN A;  3ASN A;  3ASO A;  3WFE B;  2DYS A;  3OMA A;  4G7S A;  1QLE A;  3AG1 A;  3WFB B;  5B3S A;  2EIJ A;  3O0R B;  4FA7 A;  1V55 A;  3S3B A;  3S3C A;  1AR1 A;  3QJU A;  1OCZ A;  1OCO A;  2DYR A;  3X2Q A;  3EH5 A;  3FYE A;  2QPE A;  3DTU A;  3EHB A;  4N4Y A;  2GSM A;  2OCC A;  4G7R A;  3WG7 A;  1V54 A;  4GP5 A;  1EHK A;  2EIM A;  3MK7 A;  2EIL A;  3EH4 A;  4G7Q A;  3ABL A;  4GP8 A;  3AYG A;  3OMI A;  3HB3 A;  5IY5 A;  2QPD A;  2ZXW A;  3S8F A;  1OCR A;  3ABM A;  3AYF A;  5B1B A;  5DJQ A;  3S8G A;  3OM3 A;  2YEV A;  3QJV A;  4G72 A;  3WFC B;  3ABK A;  3S3D A;  4FAA A;  3AG2 A;  4G71 A;  3EH3 A;  4XYD A;  1OCC A;  1XME A;  3QJS A;  3AG4 A;  2Y69 A;  1FFT A;  1M56 A;  3FYI A;  4GP4 A;  3QJR A;  1M57 A;  2EIN A;  3BVD A;  3QJQ A;  5B1A A;  2EIK A;  4G70 A;  3QJT A;  3WFD B;  3AG3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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