3GMHA

Crystal structure of the mad2 dimer
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
193
structure length
193
Chain Sequence
SITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLELIKYLNNVVEQLKDWLYKCSVQKLVVVISNIESGEVLERWQFDIECDKTAKDDSAPREKSQKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVVPEKWEESGPQFITNSEEVRLRSFTTTIHKVNSMVAYKIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of an intermediate conformer of the spindle checkpoint protein Mad2.
pubmed doi rcsb
molecule keywords Mitotic spindle assembly checkpoint protein MAD2A
molecule tags Cell cycle
source organism Homo sapiens
total genus 50
structure length 193
sequence length 193
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L
ec nomenclature
pdb deposition date 2009-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02301 HORMA HORMA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.900.10 Alpha Beta 2-Layer Sandwich Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A HORMA domain 3gmhA00
4TZNA 5C50B 1GO4A 1S2HA 3VU7C 4TZJA 1KLQA 4TZLA 2V64D 4GK0A 4EXTC 5LCWZ 3ABEC 4AEZB 4GK5A 3ABDA 4TZOA 1DUJA 4TZMA 2QYFA 2VFXA 4FJOC 3GMHA 4J2GA 2V64A 4TZQA 4TRKA 4TZSA 4YK8B
chains in the Genus database with same CATH superfamily
4TZNA 5C50B 1GO4A 1S2HA 3VU7C 4TZJA 1KLQA 4TZLA 2V64D 4GK0A 4EXTC 5LCWZ 3ABEC 4AEZB 4GK5A 3ABDA 4TZOA 2QYFB 1DUJA 4TZMA 2QYFA 2VFXA 4FJOC 3GMHA 4J2GA 2V64A 4TZQA 4TRKA 4TZSA 4YK8B
chains in the Genus database with same CATH topology
4TZNA 5C50B 1GO4A 1S2HA 3VU7C 4TZJA 1KLQA 4TZLA 2V64D 4GK0A 4EXTC 5LCWZ 3ABEC 4AEZB 4GK5A 3ABDA 4TZOA 1DUJA 4TZMA 2QYFA 2VFXA 4FJOC 3GMHA 4J2GA 2V64A 4TZQA 4TRKA 4TZSA 4YK8B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TZN A;  5C50 B;  1GO4 A;  1S2H A;  3VU7 C;  4TZJ A;  1KLQ A;  4TZL A;  2V64 D;  4GK0 A;  4EXT C;  5LCW Z;  3ABE C;  4AEZ B;  4GK5 A;  3ABD A;  4TZO A;  1DUJ A;  4TZM A;  2QYF A;  2VFX A;  4FJO C;  3GMH A;  4J2G A;  2V64 A;  4TZQ A;  4TRK A;  4TZS A;  4YK8 B; 
#chains in the Genus database with same CATH topology
 4TZN A;  5C50 B;  1GO4 A;  1S2H A;  3VU7 C;  4TZJ A;  1KLQ A;  4TZL A;  2V64 D;  4GK0 A;  4EXT C;  5LCW Z;  3ABE C;  4AEZ B;  4GK5 A;  3ABD A;  4TZO A;  2QYF B;  1DUJ A;  4TZM A;  2QYF A;  2VFX A;  4FJO C;  3GMH A;  4J2G A;  2V64 A;  4TZQ A;  4TRK A;  4TZS A;  4YK8 B; 
#chains in the Genus database with same CATH homology
 4TZN A;  5C50 B;  1GO4 A;  1S2H A;  3VU7 C;  4TZJ A;  1KLQ A;  4TZL A;  2V64 D;  4GK0 A;  4EXT C;  5LCW Z;  3ABE C;  4AEZ B;  4GK5 A;  3ABD A;  4TZO A;  1DUJ A;  4TZM A;  2QYF A;  2VFX A;  4FJO C;  3GMH A;  4J2G A;  2V64 A;  4TZQ A;  4TRK A;  4TZS A;  4YK8 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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