3KI3A

Catalytic fragment of cholix toxin from vibrio cholerae in complex with inhibitor gp-h
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
208
structure length
198
Chain Sequence
MAVITPQGVTNWTYQELEATHQALTREGYVFVGYHGTNHVAAQTIVNRIAPEKWGGLYVATHAEVAHGYARIKEGTGEYGLPTRAERDARGVMLRVYIPRASLERFYRTNTPLENAEEHITQVIGHSLPLRNEAFTGPESAGGEDETVIGWDMAIHAVAIPSTIPGNAYEELAIDEEAVAKEQSISTKPPYKERKDEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae
rcsb
molecule tags Transferase,toxin
source organism Vibrio cholerae
molecule keywords Cholix toxin
total genus 54
structure length 198
sequence length 208
ec nomenclature ec 2.4.2.36: NAD(+)--diphthamide ADP-ribosyltransferase.
pdb deposition date 2009-10-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09009 Exotox-A_cataly Exotoxin A catalytic
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.175.10 Alpha Beta Alpha-Beta Complex Diphtheria Toxin; domain 1 Diphtheria Toxin, domain 1 3ki3A00
1ZM9B 3KI7A 3KI0A 3ESSA 3KI6A 5I82A 1ZM2B 1MDTA 3KI5A 1F0LA 1ZM3B 2Q6MA 1IKQA 1DMAA 3NY6A 3Q9OA 1ZM4B 1SGKA 1TOXA 2ZITB 3KI4A 3KI3A 1AERA 1DDTA 4OW6A 1DTPA 1IKPA 1XK9A 4AE1A 3B82B 3B78B 3KI2A 2Q5TA 3B8HB 3KI1A 1XDTT 4AE0A
chains in the Genus database with same CATH superfamily
1ZM9B 3KI7A 3KI0A 3ESSA 3KI6A 5I82A 1ZM2B 1MDTA 3KI5A 1F0LA 1ZM3B 2Q6MA 1IKQA 1DMAA 3NY6A 3Q9OA 1ZM4B 1SGKA 1TOXA 2ZITB 3KI4A 3KI3A 1AERA 1DDTA 4OW6A 1DTPA 1IKPA 1XK9A 4AE1A 3B82B 3B78B 3KI2A 2Q5TA 3B8HB 3KI1A 1XDTT 4AE0A
chains in the Genus database with same CATH topology
1ZM9B 3KI7A 3KI0A 3ESSA 3KI6A 5I82A 1ZM2B 1MDTA 3KI5A 1F0LA 1ZM3B 2Q6MA 1IKQA 1DMAA 3NY6A 3Q9OA 1ZM4B 1SGKA 1TOXA 2ZITB 3KI4A 3KI3A 1AERA 1DDTA 4OW6A 1DTPA 1IKPA 1XK9A 4AE1A 3B82B 3B78B 3KI2A 2Q5TA 3B8HB 3KI1A 1XDTT 4AE0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZM9 B;  3KI7 A;  3KI0 A;  3ESS A;  3KI6 A;  5I82 A;  1ZM2 B;  1MDT A;  3KI5 A;  1F0L A;  1ZM3 B;  2Q6M A;  1IKQ A;  1DMA A;  3NY6 A;  3Q9O A;  1ZM4 B;  1SGK A;  1TOX A;  2ZIT B;  3KI4 A;  3KI3 A;  1AER A;  1DDT A;  4OW6 A;  1DTP A;  1IKP A;  1XK9 A;  4AE1 A;  3B82 B;  3B78 B;  3KI2 A;  2Q5T A;  3B8H B;  3KI1 A;  1XDT T;  4AE0 A; 
#chains in the Genus database with same CATH topology
 1ZM9 B;  3KI7 A;  3KI0 A;  3ESS A;  3KI6 A;  5I82 A;  1ZM2 B;  1MDT A;  3KI5 A;  1F0L A;  1ZM3 B;  2Q6M A;  1IKQ A;  1DMA A;  3NY6 A;  3Q9O A;  1ZM4 B;  1SGK A;  1TOX A;  2ZIT B;  3KI4 A;  3KI3 A;  1AER A;  1DDT A;  4OW6 A;  1DTP A;  1IKP A;  1XK9 A;  4AE1 A;  3B82 B;  3B78 B;  3KI2 A;  2Q5T A;  3B8H B;  3KI1 A;  1XDT T;  4AE0 A; 
#chains in the Genus database with same CATH homology
 1ZM9 B;  3KI7 A;  3KI0 A;  3ESS A;  3KI6 A;  5I82 A;  1ZM2 B;  1MDT A;  3KI5 A;  1F0L A;  1ZM3 B;  2Q6M A;  1IKQ A;  1DMA A;  3NY6 A;  3Q9O A;  1ZM4 B;  1SGK A;  1TOX A;  2ZIT B;  3KI4 A;  3KI3 A;  1AER A;  1DDT A;  4OW6 A;  1DTP A;  1IKP A;  1XK9 A;  4AE1 A;  3B82 B;  3B78 B;  3KI2 A;  2Q5T A;  3B8H B;  3KI1 A;  1XDT T;  4AE0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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