3RETA

Salicylate and pyruvate bound structure of the isochorismate-pyruvate lyase k42e mutant from pseudomonas aerugionsa
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
97
structure length
97
Chain Sequence
MKTPEDCTGLADIREAIDRIDLDIVQALGRRMDYVKAASRFEASEAAIPAPERVAAMLPERARWAEENGLDAPFVEGLFAQIIHWYIAEQIKYWRQT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title pH Dependence of Catalysis by Pseudomonas aeruginosa Isochorismate-Pyruvate Lyase: Implications for Transition State Stabilization and the Role of Lysine 42.
pubmed doi rcsb
molecule tags Lyase
source organism Pseudomonas aeruginosa
molecule keywords Salicylate biosynthesis protein pchB
total genus 38
structure length 97
sequence length 97
chains with identical sequence B
ec nomenclature ec 4.2.99.21: Isochorismate lyase.
pdb deposition date 2011-04-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01817 CM_2 Chorismate mutase type II
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.59.10 Mainly Alpha Up-down Bundle Chorismate Mutase Domain, subunit A Chorismate mutase 3retA00
1ECMA 2QBVA 2W1AC 5CKXC 3HGXA 3RETA 2H9CA 2GTVX 3NVTA 3HGWA 3TFCA 2D8EA 1YBZA 2VKLA 2H9DA 3RMIA 2D8DA 3REMA 2W19C
chains in the Genus database with same CATH superfamily
1ECMA 1NI5A 2QBVA 2W1AC 5CKXC 2E21A 3HGXA 2H9CA 3RETA 2GTVX 3NVTA 3HGWA 1WY5A 3TFCA 2E89A 2D8EA 1YBZA 2VKLA 2H9DA 3RMIA 3A2KA 2D8DA 3REMA 2W19C
chains in the Genus database with same CATH topology
1ECMA 2QBVA 2W1AC 5CKXC 3HGXA 3RETA 2H9CA 2GTVX 3NVTA 3HGWA 3TFCA 2D8EA 1YBZA 2VKLA 2H9DA 3RMIA 2D8DA 3REMA 2W19C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ECM A;  2QBV A;  2W1A C;  5CKX C;  3HGX A;  3RET A;  2H9C A;  2GTV X;  3NVT A;  3HGW A;  3TFC A;  2D8E A;  1YBZ A;  2VKL A;  2H9D A;  3RMI A;  2D8D A;  3REM A;  2W19 C; 
#chains in the Genus database with same CATH topology
 1ECM A;  1NI5 A;  2QBV A;  2W1A C;  5CKX C;  2E21 A;  3HGX A;  2H9C A;  3RET A;  2GTV X;  3NVT A;  3HGW A;  1WY5 A;  3TFC A;  2E89 A;  2D8E A;  1YBZ A;  2VKL A;  2H9D A;  3RMI A;  3A2K A;  2D8D A;  3REM A;  2W19 C; 
#chains in the Genus database with same CATH homology
 1ECM A;  2QBV A;  2W1A C;  5CKX C;  3HGX A;  3RET A;  2H9C A;  2GTV X;  3NVT A;  3HGW A;  3TFC A;  2D8E A;  1YBZ A;  2VKL A;  2H9D A;  3RMI A;  2D8D A;  3REM A;  2W19 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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