The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
135
|
sequence length |
421
|
structure length |
421
|
Chain Sequence |
PGAEDLEITKLPNGLIIASLENFSPASRIGVFIKAGSRYETTANLGTAHLLRLASPLTTKGASSFRITRGIEAVGGSLSVYSTREKMTYCVECLRDHVDTVMEYLLNVTTAPEFRPWEVTDLQPQLKVDKAVAFQSPQVGVLENLHAAAYKTALANPLYCPDYRIGKITSEQLHHFVQNNFTSARMALVGIGVKHSDLKQVAEQFLNIRSGAGTSSAKATYWGGEIREQNGHSLVHAAVVTEGAAVGSAEANAFSVLQHVLGAGPLIKRGSSVTSKLYQGVAKATTQPFDASAFNVNYSDSGLFGFYTISQAAHAGEVIRAAMNQLKAAAQGGVTEEDVTKAKNQLKATYLMSVETAQGLLNEIGSEALLSGTHTAPSVVAQKIDSVTSADVVNAAKKFVSGKKSMAASGDLGSTPFLDEL
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| molecule tags |
Oxidoreductase/oxidoreductase inhibitor
|
| molecule keywords |
Mitochondrial ubiquinol-cytochrome-c reductase complex core
|
| publication title |
Computational discovery of picomolar Q(o) site inhibitors of cytochrome bc1 complex.
pubmed doi rcsb |
| total genus |
135
|
| structure length |
421
|
| sequence length |
421
|
| chains with identical sequence |
O
|
| ec nomenclature | |
| pdb deposition date | 2011-08-17 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| B | PF00675 | Peptidase_M16 | Insulinase (Peptidase family M16) |
| B | PF05193 | Peptidase_M16_C | Peptidase M16 inactive domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 2-Layer Sandwich | Cytochrome Bc1 Complex; Chain A, domain 1 | Metalloenzyme, LuxS/M16 peptidase-like | ||
| Alpha Beta | 2-Layer Sandwich | Cytochrome Bc1 Complex; Chain A, domain 1 | Metalloenzyme, LuxS/M16 peptidase-like |
#chains in the Genus database with same CATH superfamily 1HR8 A; 4U3F A; 2BCC A; 1KYO A; 1NTM B; 1SQB B; 1HR9 A; 1NTK A; 1Q2L A; 1BCC A; 2JBU A; 4RPU A; 2G56 A; 3H1H B; 3IVL A; 1EZV B; 3BCC A; 1L0L A; 1L0N B; 3H1J A; 1PP9 B; 5CJO A; 3L74 A; 4GSC A; 2A06 B; 4RAL A; 4IOF A; 3AMJ A; 2IBZ A; 1NTZ B; 4PF7 A; 4D6T B; 1HR6 A; 1KB9 B; 2WC0 A; 3H1L A; 4PD4 A; 4IFH A; 3TGU B; 3L71 A; 4PF9 A; 1HR8 B; 4U3F B; 2BCC B; 4NGE A; 3AMI A; 3TUV A; 1KYO B; 1HR9 B; 1NTK B; 3N57 A; 1BCC B; 4RPU B; 3BCC B; 1BE3 A; 3H1I A; 4DTT A; 1L0L B; 3L70 A; 3CWW A; 3H1J B; 2JG4 A; 3L74 B; 2FGE A; 2WK3 A; 2YPU A; 1HR7 A; 4L3T A; 3CX5 A; 3AMJ B; 2IBZ B; 2G49 A; 3L75 B; 3IH6 A; 1HR6 B; 4D6T O; 3L75 A; 3E50 A; 4PES A; 3H1L B; 4PD4 B; 4DWK A; 3CXH A; 3L71 B; 1SQQ A; 2G48 A; 3D3Y A; 3H1K A; 1PPJ A; 1BGY B; 3OFI A; 4PFC A; 3H1I B; 1BE3 B; 1BGY A; 3L70 B; 2FYU B; 1NU1 A; 1SQX A; 3E4A A; 2FYU A; 3QZ2 A; 2G47 A; 1P84 B; 4XEA A; 1SQV B; 1SQP A; 1HR7 B; 4L3T B; 1P84 A; 3CX5 B; 3CWB B; 1SQV A; 3L72 A; 3GO9 A; 3CWB A; 5KLV A; 4M1C A; 3HDI A; 3L73 A; 3CXH B; 3EOQ A; 1SQQ B; 3H44 A; 3H1K B; 1NTM A; 1SQB A; 3HGZ A; 3N56 A; 3P7O A; 1PPJ B; 5EUF A; 2G54 A; 1NU1 B; 1SQX B; 3H1H A; 4NXO A; 1EZV A; 4RE9 A; 4LTE A; 1L0N A; 4QIA A; 3GWB A; 1PP9 A; 1SQP B; 3L72 B; 4NGE D; 2A06 A; 3E4Z A; 4NNZ A; 4GS8 A; 5KLV B; 1NTZ A; 4D6T A; 1KB9 A; 3L73 B; 3TGU A; 4GSF A; 3P7L A; 2WBY A; #chains in the Genus database with same CATH topology 1HR8 A; 4U3F A; 2BCC A; 1KYO A; 1NTM B; 1SQB B; 1HR9 A; 1NTK A; 1Q2L A; 1BCC A; 2JBU A; 4RPU A; 2G56 A; 3H1H B; 3IVL A; 1EZV B; 3BCC A; 1L0L A; 1L0N B; 3H1J A; 1PP9 B; 5CJO A; 3L74 A; 4GSC A; 2A06 B; 4RAL A; 4IOF A; 3AMJ A; 2IBZ A; 1NTZ B; 4PF7 A; 4D6T B; 1HR6 A; 1KB9 B; 2WC0 A; 3H1L A; 4PD4 A; 4IFH A; 3TGU B; 3L71 A; 4PF9 A; 1HR8 B; 4U3F B; 2BCC B; 4NGE A; 3AMI A; 3TUV A; 1KYO B; 1HR9 B; 1NTK B; 3N57 A; 1BCC B; 4RPU B; 3BCC B; 1BE3 A; 3H1I A; 4DTT A; 1L0L B; 3L70 A; 3CWW A; 3H1J B; 2JG4 A; 3L74 B; 2FGE A; 2WK3 A; 2YPU A; 1HR7 A; 4L3T A; 3CX5 A; 3AMJ B; 2IBZ B; 2G49 A; 3L75 B; 3IH6 A; 1HR6 B; 4D6T O; 3L75 A; 3E50 A; 4PES A; 3H1L B; 4PD4 B; 4DWK A; 3CXH A; 3L71 B; 1SQQ A; 2G48 A; 3D3Y A; 3H1K A; 1PPJ A; 1BGY B; 3OFI A; 4PFC A; 3H1I B; 1BE3 B; 1BGY A; 3L70 B; 2FYU B; 1NU1 A; 1SQX A; 3E4A A; 2FYU A; 3QZ2 A; 2G47 A; 1P84 B; 4XEA A; 1SQV B; 1SQP A; 1HR7 B; 4L3T B; 1P84 A; 3CX5 B; 3CWB B; 1SQV A; 3L72 A; 3GO9 A; 3CWB A; 5KLV A; 4M1C A; 3HDI A; 3L73 A; 3CXH B; 3EOQ A; 1SQQ B; 3H44 A; 3H1K B; 1NTM A; 1SQB A; 3HGZ A; 3N56 A; 3P7O A; 1PPJ B; 5EUF A; 2G54 A; 1NU1 B; 1SQX B; 3H1H A; 4NXO A; 1EZV A; 4RE9 A; 4LTE A; 1L0N A; 4QIA A; 3GWB A; 1PP9 A; 1SQP B; 3L72 B; 4NGE D; 2A06 A; 3E4Z A; 4NNZ A; 4GS8 A; 5KLV B; 1NTZ A; 4D6T A; 1KB9 A; 3L73 B; 3TGU A; 4GSF A; 3P7L A; 2WBY A; #chains in the Genus database with same CATH homology 1HR8 A; 4U3F A; 2BCC A; 1KYO A; 1NTM B; 1SQB B; 1HR9 A; 1NTK A; 1Q2L A; 1BCC A; 2JBU A; 4RPU A; 2G56 A; 3H1H B; 3IVL A; 1EZV B; 3BCC A; 1L0L A; 1L0N B; 3H1J A; 1PP9 B; 5CJO A; 3L74 A; 4GSC A; 2A06 B; 4RAL A; 4IOF A; 3AMJ A; 2IBZ A; 1NTZ B; 4PF7 A; 4D6T B; 1HR6 A; 1KB9 B; 2WC0 A; 3H1L A; 4PD4 A; 4IFH A; 3TGU B; 3L71 A; 4PF9 A; 1HR8 B; 4U3F B; 2BCC B; 4NGE A; 3AMI A; 3TUV A; 1KYO B; 1HR9 B; 1NTK B; 3N57 A; 1BCC B; 4RPU B; 3BCC B; 1BE3 A; 3H1I A; 4DTT A; 1L0L B; 3L70 A; 3CWW A; 3H1J B; 2JG4 A; 3L74 B; 2FGE A; 2WK3 A; 2YPU A; 1HR7 A; 4L3T A; 3CX5 A; 3AMJ B; 2IBZ B; 2G49 A; 3L75 B; 3IH6 A; 1HR6 B; 4D6T O; 3L75 A; 3E50 A; 4PES A; 3H1L B; 4PD4 B; 4DWK A; 3CXH A; 3L71 B; 1SQQ A; 2G48 A; 3D3Y A; 3H1K A; 1PPJ A; 1BGY B; 3OFI A; 4PFC A; 3H1I B; 1BE3 B; 1BGY A; 3L70 B; 2FYU B; 1NU1 A; 1SQX A; 3E4A A; 2FYU A; 3QZ2 A; 2G47 A; 1P84 B; 4XEA A; 1SQV B; 1SQP A; 1HR7 B; 4L3T B; 1P84 A; 3CX5 B; 3CWB B; 1SQV A; 3L72 A; 3GO9 A; 3CWB A; 5KLV A; 4M1C A; 3HDI A; 3L73 A; 3CXH B; 3EOQ A; 1SQQ B; 3H44 A; 3H1K B; 1NTM A; 1SQB A; 3HGZ A; 3N56 A; 3P7O A; 1PPJ B; 5EUF A; 2G54 A; 1NU1 B; 1SQX B; 3H1H A; 4NXO A; 1EZV A; 4RE9 A; 4LTE A; 1L0N A; 4QIA A; 3GWB A; 1PP9 A; 1SQP B; 3L72 B; 4NGE D; 2A06 A; 3E4Z A; 4NNZ A; 4GS8 A; 5KLV B; 1NTZ A; 4D6T A; 1KB9 A; 3L73 B; 3TGU A; 4GSF A; 3P7L A; 2WBY A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
