3TGUI

Cytochrome bc1 complex from chicken with pfvs-designed moa inhibitor bound
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
74
structure length
51
Chain Sequence
LSVAARSXXXXXXXXXXXXXXPLLCRESMSGRSARRDLVAGISLNAPASVR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Computational discovery of picomolar Q(o) site inhibitors of cytochrome bc1 complex.
pubmed doi rcsb
molecule keywords Mitochondrial ubiquinol-cytochrome-c reductase complex core
molecule tags Oxidoreductase/oxidoreductase inhibitor
total genus 1
structure length 51
sequence length 74
chains with identical sequence V
ec nomenclature ec 7.1.1.8: Quinol--cytochrome-c reductase.
pdb deposition date 2011-08-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF09165 Ubiq-Cytc-red_N Ubiquinol-cytochrome c reductase 8 kDa, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.210.10 Mainly Beta Ribbon Cytochrome Bc1 Complex; Chain I Cytochrome Bc1 Complex; Chain I 3tguI00
1L0LI 1SQQI 1SQVI 2A06I 3L70I 3H1KI 3TGUI 1SQPI 3L73I 3H1LI 3L74I 1NTZI 2FYUI 3L72I 1NTKI 1SQBI 3H1JI 1NU1I 1PPJI 4U3FI 1PP9I 3H1II 3L75I 3CWBI 1L0NI 3H1HI 3L71I 1SQXI 1NTMI
chains in the Genus database with same CATH superfamily
1L0LI 1SQQI 1SQVI 2A06I 3L70I 3H1KI 3TGUI 1SQPI 3L73I 3H1LI 3L74I 1NTZI 2FYUI 3L72I 1NTKI 1SQBI 3H1JI 1NU1I 1PPJI 4U3FI 1PP9I 3H1II 3L75I 3CWBI 1L0NI 3H1HI 3L71I 1SQXI 1NTMI
chains in the Genus database with same CATH topology
1L0LI 1SQQI 1SQVI 2A06I 3L70I 3H1KI 3TGUI 1SQPI 3L73I 3H1LI 3L74I 1NTZI 2FYUI 3L72I 1NTKI 1SQBI 3H1JI 1NU1I 1PPJI 4U3FI 1PP9I 3H1II 3L75I 3CWBI 1L0NI 3H1HI 3L71I 1SQXI 1NTMI
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1L0L I;  1SQQ I;  1SQV I;  2A06 I;  3L70 I;  3H1K I;  3TGU I;  1SQP I;  3L73 I;  3H1L I;  3L74 I;  1NTZ I;  2FYU I;  3L72 I;  1NTK I;  1SQB I;  3H1J I;  1NU1 I;  1PPJ I;  4U3F I;  1PP9 I;  3H1I I;  3L75 I;  3CWB I;  1L0N I;  3H1H I;  3L71 I;  1SQX I;  1NTM I; 
#chains in the Genus database with same CATH topology
 1L0L I;  1SQQ I;  1SQV I;  2A06 I;  3L70 I;  3H1K I;  3TGU I;  1SQP I;  3L73 I;  3H1L I;  3L74 I;  1NTZ I;  2FYU I;  3L72 I;  1NTK I;  1SQB I;  3H1J I;  1NU1 I;  1PPJ I;  4U3F I;  1PP9 I;  3H1I I;  3L75 I;  3CWB I;  1L0N I;  3H1H I;  3L71 I;  1SQX I;  1NTM I; 
#chains in the Genus database with same CATH homology
 1L0L I;  1SQQ I;  1SQV I;  2A06 I;  3L70 I;  3H1K I;  3TGU I;  1SQP I;  3L73 I;  3H1L I;  3L74 I;  1NTZ I;  2FYU I;  3L72 I;  1NTK I;  1SQB I;  3H1J I;  1NU1 I;  1PPJ I;  4U3F I;  1PP9 I;  3H1I I;  3L75 I;  3CWB I;  1L0N I;  3H1H I;  3L71 I;  1SQX I;  1NTM I;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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