3AG1A

Bovine heart cytochrome c oxidase in the carbon monoxide-bound fully reduced state at 280 k
Total Genus 207
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
207
sequence length
513
structure length
513
Chain Sequence
FINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Bovine cytochrome c oxidase structures enable O2 reduction with minimization of reactive oxygens and provide a proton-pumping gate
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Cytochrome c oxidase subunit 1
total genus 207
structure length 513
sequence length 513
chains with identical sequence N
ec nomenclature ec 1.9.3.1: Cytochrome-c oxidase.
pdb deposition date 2010-03-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00115 COX1 Cytochrome C and Quinol oxidase polypeptide I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase; Chain A Cytochrome c oxidase-like, subunit I domain 3ag1A00
1FFTA 4G7RA 2QPEA 3DTUA 2EIKA 3WFBB 4XYDA 2Y69A 2EILA 4G71A 2EINA 3ASNA 1OCCA 1V55A 2DYRA 3QJVA 5B1BA 2YEVA 3S8FA 3O0RB 3AG3A 3EHBA 4GP5A 3AG1A 1M56A 3QJRA 5IY5A 3OMNA 3EH3A 3BVDA 4G7QA 3ABLA 3FYIA 4N4YA 3QJSA 3HB3A 3FYEA 1M57A 3QJTA 1OCZA 3AG2A 3QJUA 3ABMA 3WFDB 5B1AA 3QJQA 3MK7A 3OM3A 5DJQA 3S3BA 2EIMA 1OCRA 4FAAA 3EH4A 1AR1A 1V54A 3WFEB 3AG4A 3OMIA 2ZXWA 1OCOA 4G7SA 3WFCB 2OCCA 4GP4A 4GP8A 3ABKA 3S3CA 3S8GA 3ASOA 3AYGA 1XMEA 2DYSA 3WG7A 5B3SA 3AYFA 3OMAA 3X2QA 4FA7A 2EIJA 4G72A 1QLEA 4G70A 3S3DA 2GSMA 2QPDA 3EH5A 1EHKA
chains in the Genus database with same CATH superfamily
1FFTA 4G7RA 2QPEA 3DTUA 2EIKA 3WFBB 4XYDA 2Y69A 2EILA 4G71A 2EINA 3ASNA 1OCCA 1V55A 2DYRA 3QJVA 5B1BA 2YEVA 3S8FA 3O0RB 3AG3A 3EHBA 4GP5A 3AG1A 1M56A 3QJRA 5IY5A 3OMNA 3EH3A 3BVDA 4G7QA 3ABLA 3FYIA 4N4YA 3QJSA 3HB3A 3FYEA 1M57A 3QJTA 1OCZA 3AG2A 3QJUA 3ABMA 3WFDB 5B1AA 3QJQA 3MK7A 3OM3A 5DJQA 3S3BA 2EIMA 1OCRA 4FAAA 3EH4A 1AR1A 1V54A 3WFEB 3AG4A 3OMIA 2ZXWA 1OCOA 4G7SA 3WFCB 2OCCA 4GP4A 4GP8A 3ABKA 3S3CA 3S8GA 3ASOA 3AYGA 1XMEA 2DYSA 3WG7A 5B3SA 3AYFA 3OMAA 3X2QA 4FA7A 2EIJA 4G72A 1QLEA 4G70A 3S3DA 2GSMA 2QPDA 3EH5A 1EHKA
chains in the Genus database with same CATH topology
1FFTA 4G7RA 2QPEA 3DTUA 2EIKA 3WFBB 4XYDA 2Y69A 2EILA 4G71A 2EINA 3ASNA 1OCCA 1V55A 2DYRA 3QJVA 5B1BA 2YEVA 3S8FA 3O0RB 3AG3A 3EHBA 4GP5A 3AG1A 1M56A 3QJRA 5IY5A 3OMNA 3EH3A 3BVDA 4G7QA 3ABLA 3FYIA 4N4YA 3QJSA 3HB3A 3FYEA 1M57A 3QJTA 1OCZA 3AG2A 3QJUA 3ABMA 3WFDB 5B1AA 3QJQA 3MK7A 3OM3A 5DJQA 3S3BA 2EIMA 1OCRA 4FAAA 3EH4A 1AR1A 1V54A 3WFEB 3AG4A 3OMIA 2ZXWA 1OCOA 4G7SA 3WFCB 2OCCA 4GP4A 4GP8A 3ABKA 3S3CA 3S8GA 3ASOA 3AYGA 1XMEA 2DYSA 3WG7A 5B3SA 3AYFA 3OMAA 3X2QA 4FA7A 2EIJA 4G72A 1QLEA 4G70A 3S3DA 2GSMA 2QPDA 3EH5A 1EHKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FFT A;  4G7R A;  2QPE A;  3DTU A;  2EIK A;  3WFB B;  4XYD A;  2Y69 A;  2EIL A;  4G71 A;  2EIN A;  3ASN A;  1OCC A;  1V55 A;  2DYR A;  3QJV A;  5B1B A;  2YEV A;  3S8F A;  3O0R B;  3AG3 A;  3EHB A;  4GP5 A;  3AG1 A;  1M56 A;  3QJR A;  5IY5 A;  3OMN A;  3EH3 A;  3BVD A;  4G7Q A;  3ABL A;  3FYI A;  4N4Y A;  3QJS A;  3HB3 A;  3FYE A;  1M57 A;  3QJT A;  1OCZ A;  3AG2 A;  3QJU A;  3ABM A;  3WFD B;  5B1A A;  3QJQ A;  3MK7 A;  3OM3 A;  5DJQ A;  3S3B A;  2EIM A;  1OCR A;  4FAA A;  3EH4 A;  1AR1 A;  1V54 A;  3WFE B;  3AG4 A;  3OMI A;  2ZXW A;  1OCO A;  4G7S A;  3WFC B;  2OCC A;  4GP4 A;  4GP8 A;  3ABK A;  3S3C A;  3S8G A;  3ASO A;  3AYG A;  1XME A;  2DYS A;  3WG7 A;  5B3S A;  3AYF A;  3OMA A;  3X2Q A;  4FA7 A;  2EIJ A;  4G72 A;  1QLE A;  4G70 A;  3S3D A;  2GSM A;  2QPD A;  3EH5 A;  1EHK A; 
#chains in the Genus database with same CATH topology
 1FFT A;  4G7R A;  2QPE A;  3DTU A;  2EIK A;  3WFB B;  4XYD A;  2Y69 A;  2EIL A;  4G71 A;  2EIN A;  3ASN A;  1OCC A;  1V55 A;  2DYR A;  3QJV A;  5B1B A;  2YEV A;  3S8F A;  3O0R B;  3AG3 A;  3EHB A;  4GP5 A;  3AG1 A;  1M56 A;  3QJR A;  5IY5 A;  3OMN A;  3EH3 A;  3BVD A;  4G7Q A;  3ABL A;  3FYI A;  4N4Y A;  3QJS A;  3HB3 A;  3FYE A;  1M57 A;  3QJT A;  1OCZ A;  3AG2 A;  3QJU A;  3ABM A;  3WFD B;  5B1A A;  3QJQ A;  3MK7 A;  3OM3 A;  5DJQ A;  3S3B A;  2EIM A;  1OCR A;  4FAA A;  3EH4 A;  1AR1 A;  1V54 A;  3WFE B;  3AG4 A;  3OMI A;  2ZXW A;  1OCO A;  4G7S A;  3WFC B;  2OCC A;  4GP4 A;  4GP8 A;  3ABK A;  3S3C A;  3S8G A;  3ASO A;  3AYG A;  1XME A;  2DYS A;  3WG7 A;  5B3S A;  3AYF A;  3OMA A;  3X2Q A;  4FA7 A;  2EIJ A;  4G72 A;  1QLE A;  4G70 A;  3S3D A;  2GSM A;  2QPD A;  3EH5 A;  1EHK A; 
#chains in the Genus database with same CATH homology
 1FFT A;  4G7R A;  2QPE A;  3DTU A;  2EIK A;  3WFB B;  4XYD A;  2Y69 A;  2EIL A;  4G71 A;  2EIN A;  3ASN A;  1OCC A;  1V55 A;  2DYR A;  3QJV A;  5B1B A;  2YEV A;  3S8F A;  3O0R B;  3AG3 A;  3EHB A;  4GP5 A;  3AG1 A;  1M56 A;  3QJR A;  5IY5 A;  3OMN A;  3EH3 A;  3BVD A;  4G7Q A;  3ABL A;  3FYI A;  4N4Y A;  3QJS A;  3HB3 A;  3FYE A;  1M57 A;  3QJT A;  1OCZ A;  3AG2 A;  3QJU A;  3ABM A;  3WFD B;  5B1A A;  3QJQ A;  3MK7 A;  3OM3 A;  5DJQ A;  3S3B A;  2EIM A;  1OCR A;  4FAA A;  3EH4 A;  1AR1 A;  1V54 A;  3WFE B;  3AG4 A;  3OMI A;  2ZXW A;  1OCO A;  4G7S A;  3WFC B;  2OCC A;  4GP4 A;  4GP8 A;  3ABK A;  3S3C A;  3S8G A;  3ASO A;  3AYG A;  1XME A;  2DYS A;  3WG7 A;  5B3S A;  3AYF A;  3OMA A;  3X2Q A;  4FA7 A;  2EIJ A;  4G72 A;  1QLE A;  4G70 A;  3S3D A;  2GSM A;  2QPD A;  3EH5 A;  1EHK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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