3AG2A

Bovine heart cytochrome c oxidase in the carbon monoxide-bound fully reduced state at 100 k
Total Genus 211
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
211
sequence length
513
structure length
513
Chain Sequence
FINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Bovine cytochrome c oxidase structures enable O2 reduction with minimization of reactive oxygens and provide a proton-pumping gate
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Cytochrome c oxidase subunit 1
total genus 211
structure length 513
sequence length 513
chains with identical sequence N
ec nomenclature ec 1.9.3.1: Cytochrome-c oxidase.
pdb deposition date 2010-03-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00115 COX1 Cytochrome C and Quinol oxidase polypeptide I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase; Chain A Cytochrome c oxidase-like, subunit I domain 3ag2A00
2EINA 2DYRA 3QJRA 3AG1A 1OCOA 1FFTA 3S3BA 3QJQA 3AG4A 4G72A 2GSMA 2YEVA 3OMAA 3QJTA 3BVDA 3AG2A 3ABLA 4GP4A 4GP5A 4FA7A 3O0RB 4GP8A 3OM3A 3WFEB 1M56A 1EHKA 4G7QA 3ASOA 5DJQA 1V55A 5IY5A 3ASNA 1V54A 3S8FA 3QJSA 3EH3A 3MK7A 3AYGA 1OCZA 3ABKA 4G7RA 4XYDA 2OCCA 3S3CA 3EH5A 3X2QA 2ZXWA 3AYFA 4G71A 3AG3A 2QPDA 3OMNA 3WFCB 1AR1A 1OCRA 5B1BA 1OCCA 3ABMA 2EIMA 4N4YA 5B1AA 3DTUA 1XMEA 4G7SA 2EIJA 3WG7A 3S8GA 2QPEA 3QJVA 3EH4A 3HB3A 2EIKA 1M57A 5B3SA 3S3DA 4G70A 2Y69A 2DYSA 3EHBA 3OMIA 3QJUA 3WFDB 1QLEA 4FAAA 2EILA 3FYIA 3WFBB 3FYEA
chains in the Genus database with same CATH superfamily
2EINA 2DYRA 3QJRA 3AG1A 1OCOA 1FFTA 3S3BA 3QJQA 3AG4A 4G72A 2GSMA 2YEVA 3OMAA 3QJTA 3BVDA 3AG2A 3ABLA 4GP4A 4GP5A 4FA7A 3O0RB 4GP8A 3OM3A 3WFEB 1M56A 1EHKA 4G7QA 3ASOA 5DJQA 1V55A 5IY5A 3ASNA 1V54A 3S8FA 3QJSA 3EH3A 3MK7A 3AYGA 1OCZA 3ABKA 4G7RA 4XYDA 2OCCA 3S3CA 3EH5A 3X2QA 2ZXWA 3AYFA 4G71A 3AG3A 2QPDA 3OMNA 3WFCB 1AR1A 1OCRA 5B1BA 1OCCA 3ABMA 2EIMA 4N4YA 5B1AA 3DTUA 1XMEA 4G7SA 2EIJA 3WG7A 3S8GA 2QPEA 3QJVA 3EH4A 3HB3A 2EIKA 1M57A 5B3SA 3S3DA 4G70A 2Y69A 2DYSA 3EHBA 3OMIA 3QJUA 3WFDB 1QLEA 4FAAA 2EILA 3FYIA 3WFBB 3FYEA
chains in the Genus database with same CATH topology
2EINA 2DYRA 3QJRA 3AG1A 1OCOA 1FFTA 3S3BA 3QJQA 3AG4A 4G72A 2GSMA 2YEVA 3OMAA 3QJTA 3BVDA 3AG2A 3ABLA 4GP4A 4GP5A 4FA7A 3O0RB 4GP8A 3OM3A 3WFEB 1M56A 1EHKA 4G7QA 3ASOA 5DJQA 1V55A 5IY5A 3ASNA 1V54A 3S8FA 3QJSA 3EH3A 3MK7A 3AYGA 1OCZA 3ABKA 4G7RA 4XYDA 2OCCA 3S3CA 3EH5A 3X2QA 2ZXWA 3AYFA 4G71A 3AG3A 2QPDA 3OMNA 3WFCB 1AR1A 1OCRA 5B1BA 1OCCA 3ABMA 2EIMA 4N4YA 5B1AA 3DTUA 1XMEA 4G7SA 2EIJA 3WG7A 3S8GA 2QPEA 3QJVA 3EH4A 3HB3A 2EIKA 1M57A 5B3SA 3S3DA 4G70A 2Y69A 2DYSA 3EHBA 3OMIA 3QJUA 3WFDB 1QLEA 4FAAA 2EILA 3FYIA 3WFBB 3FYEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EIN A;  2DYR A;  3QJR A;  3AG1 A;  1OCO A;  1FFT A;  3S3B A;  3QJQ A;  3AG4 A;  4G72 A;  2GSM A;  2YEV A;  3OMA A;  3QJT A;  3BVD A;  3AG2 A;  3ABL A;  4GP4 A;  4GP5 A;  4FA7 A;  3O0R B;  4GP8 A;  3OM3 A;  3WFE B;  1M56 A;  1EHK A;  4G7Q A;  3ASO A;  5DJQ A;  1V55 A;  5IY5 A;  3ASN A;  1V54 A;  3S8F A;  3QJS A;  3EH3 A;  3MK7 A;  3AYG A;  1OCZ A;  3ABK A;  4G7R A;  4XYD A;  2OCC A;  3S3C A;  3EH5 A;  3X2Q A;  2ZXW A;  3AYF A;  4G71 A;  3AG3 A;  2QPD A;  3OMN A;  3WFC B;  1AR1 A;  1OCR A;  5B1B A;  1OCC A;  3ABM A;  2EIM A;  4N4Y A;  5B1A A;  3DTU A;  1XME A;  4G7S A;  2EIJ A;  3WG7 A;  3S8G A;  2QPE A;  3QJV A;  3EH4 A;  3HB3 A;  2EIK A;  1M57 A;  5B3S A;  3S3D A;  4G70 A;  2Y69 A;  2DYS A;  3EHB A;  3OMI A;  3QJU A;  3WFD B;  1QLE A;  4FAA A;  2EIL A;  3FYI A;  3WFB B;  3FYE A; 
#chains in the Genus database with same CATH topology
 2EIN A;  2DYR A;  3QJR A;  3AG1 A;  1OCO A;  1FFT A;  3S3B A;  3QJQ A;  3AG4 A;  4G72 A;  2GSM A;  2YEV A;  3OMA A;  3QJT A;  3BVD A;  3AG2 A;  3ABL A;  4GP4 A;  4GP5 A;  4FA7 A;  3O0R B;  4GP8 A;  3OM3 A;  3WFE B;  1M56 A;  1EHK A;  4G7Q A;  3ASO A;  5DJQ A;  1V55 A;  5IY5 A;  3ASN A;  1V54 A;  3S8F A;  3QJS A;  3EH3 A;  3MK7 A;  3AYG A;  1OCZ A;  3ABK A;  4G7R A;  4XYD A;  2OCC A;  3S3C A;  3EH5 A;  3X2Q A;  2ZXW A;  3AYF A;  4G71 A;  3AG3 A;  2QPD A;  3OMN A;  3WFC B;  1AR1 A;  1OCR A;  5B1B A;  1OCC A;  3ABM A;  2EIM A;  4N4Y A;  5B1A A;  3DTU A;  1XME A;  4G7S A;  2EIJ A;  3WG7 A;  3S8G A;  2QPE A;  3QJV A;  3EH4 A;  3HB3 A;  2EIK A;  1M57 A;  5B3S A;  3S3D A;  4G70 A;  2Y69 A;  2DYS A;  3EHB A;  3OMI A;  3QJU A;  3WFD B;  1QLE A;  4FAA A;  2EIL A;  3FYI A;  3WFB B;  3FYE A; 
#chains in the Genus database with same CATH homology
 2EIN A;  2DYR A;  3QJR A;  3AG1 A;  1OCO A;  1FFT A;  3S3B A;  3QJQ A;  3AG4 A;  4G72 A;  2GSM A;  2YEV A;  3OMA A;  3QJT A;  3BVD A;  3AG2 A;  3ABL A;  4GP4 A;  4GP5 A;  4FA7 A;  3O0R B;  4GP8 A;  3OM3 A;  3WFE B;  1M56 A;  1EHK A;  4G7Q A;  3ASO A;  5DJQ A;  1V55 A;  5IY5 A;  3ASN A;  1V54 A;  3S8F A;  3QJS A;  3EH3 A;  3MK7 A;  3AYG A;  1OCZ A;  3ABK A;  4G7R A;  4XYD A;  2OCC A;  3S3C A;  3EH5 A;  3X2Q A;  2ZXW A;  3AYF A;  4G71 A;  3AG3 A;  2QPD A;  3OMN A;  3WFC B;  1AR1 A;  1OCR A;  5B1B A;  1OCC A;  3ABM A;  2EIM A;  4N4Y A;  5B1A A;  3DTU A;  1XME A;  4G7S A;  2EIJ A;  3WG7 A;  3S8G A;  2QPE A;  3QJV A;  3EH4 A;  3HB3 A;  2EIK A;  1M57 A;  5B3S A;  3S3D A;  4G70 A;  2Y69 A;  2DYS A;  3EHB A;  3OMI A;  3QJU A;  3WFD B;  1QLE A;  4FAA A;  2EIL A;  3FYI A;  3WFB B;  3FYE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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