3FYEA

Catalytic core subunits (i and ii) of cytochrome c oxidase from rhodobacter sphaeroides in the reduced state
Total Genus 228
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
228
sequence length
535
structure length
535
Chain Sequence
FTRWFMSTNHKDIGVLYLFTGGLVGLISVAFTVYMRMELMAPGVQFMCAEHLESGLVKGFFQSLWPSAVENCTPNGHLWNVMITGHGILMMFFVVIPALFGGFGNYFMPLHIGAPDMAFPRMNNLSYWLYVAGTSLAVASLFAPGGNGQLGSGIGWVLYPPLSTSESGYSTDLAIFAVHLSGASSILGAINMITTFLNMRAPGMTMHKVPLFAWSIFVTAWLILLALPVLAGAITMLLTDRNFGTTFFQPSGGGDPVLYQHILWFFGHPEVYIIVLPAFGIVSHVIATFAKKPIFGYLPMVYAMVAIGVLGFVVWAHHMYTAGLSLTQQSYFMMATMVIAVPTGIKIFSWIATMWGGSIELKTPMLWALGFLFLFTVGGVTGIVLSQASVDRYYHDTYYVVAHFHYVMSLGAVFGIFAGIYFWIGKMSGRQYPEWAGKLHFWMMFVGANLTFFPQHFLGRQGMPRRYIDYPEAFATWNFVSSLGAFLSFASFLFFLGVIFYTLTRGARVTANNYWNEHADTLEWTLTSPPPEHTF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Redox dependent conformational changes in cytochrome c oxidase suggest a gating mechanism for proton uptake.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Rhodobacter sphaeroides
molecule keywords Cytochrome C oxidase subunit 1
total genus 228
structure length 535
sequence length 535
chains with identical sequence C
ec nomenclature ec 1.9.3.1: Cytochrome-c oxidase.
pdb deposition date 2009-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00115 COX1 Cytochrome C and Quinol oxidase polypeptide I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase; Chain A Cytochrome c oxidase-like, subunit I domain 3fyeA00
1M56A 3OMAA 3S8FA 3EHBA 3OMNA 2ZXWA 4FA7A 3WFEB 3O0RB 1OCRA 3DTUA 4FAAA 2DYSA 4G7QA 3ABMA 3ASOA 3EH5A 3AYGA 3ABLA 1V55A 3QJTA 3QJQA 2EIKA 3AG4A 2YEVA 4GP8A 1M57A 3QJUA 3S3DA 3AG1A 1EHKA 2QPEA 3OM3A 1QLEA 4GP5A 2QPDA 3WFBB 3AG2A 3ABKA 3QJSA 2EIJA 2OCCA 3OMIA 4G7SA 3HB3A 1AR1A 5B1AA 5IY5A 3QJRA 3ASNA 4G7RA 4G71A 2EILA 4GP4A 2Y69A 3EH4A 1OCOA 4XYDA 3AG3A 1OCZA 3QJVA 1XMEA 4G72A 1V54A 3EH3A 2GSMA 4N4YA 1FFTA 2EINA 2DYRA 3S3CA 3BVDA 3WFDB 3S8GA 3WFCB 3FYEA 1OCCA 3FYIA 5DJQA 3X2QA 3S3BA 5B3SA 2EIMA 3MK7A 3WG7A 4G70A 5B1BA 3AYFA
chains in the Genus database with same CATH superfamily
1M56A 3OMAA 3S8FA 3EHBA 3OMNA 2ZXWA 4FA7A 3WFEB 3O0RB 1OCRA 3DTUA 4FAAA 2DYSA 4G7QA 3ABMA 3ASOA 3EH5A 3AYGA 3ABLA 1V55A 3QJTA 3QJQA 2EIKA 3AG4A 2YEVA 4GP8A 1M57A 3QJUA 3S3DA 3AG1A 1EHKA 2QPEA 3OM3A 1QLEA 4GP5A 2QPDA 3WFBB 3AG2A 3ABKA 3QJSA 2EIJA 2OCCA 3OMIA 4G7SA 3HB3A 1AR1A 5B1AA 5IY5A 3QJRA 3ASNA 4G7RA 4G71A 2EILA 4GP4A 2Y69A 3EH4A 1OCOA 4XYDA 3AG3A 1OCZA 3QJVA 1XMEA 4G72A 1V54A 3EH3A 2GSMA 4N4YA 1FFTA 2EINA 2DYRA 3S3CA 3BVDA 3WFDB 3S8GA 3WFCB 3FYEA 1OCCA 3FYIA 5DJQA 3X2QA 3S3BA 5B3SA 2EIMA 3MK7A 3WG7A 4G70A 5B1BA 3AYFA
chains in the Genus database with same CATH topology
1M56A 3OMAA 3S8FA 3EHBA 3OMNA 2ZXWA 4FA7A 3WFEB 3O0RB 1OCRA 3DTUA 4FAAA 2DYSA 4G7QA 3ABMA 3ASOA 3EH5A 3AYGA 3ABLA 1V55A 3QJTA 3QJQA 2EIKA 3AG4A 2YEVA 4GP8A 1M57A 3QJUA 3S3DA 3AG1A 1EHKA 2QPEA 3OM3A 1QLEA 4GP5A 2QPDA 3WFBB 3AG2A 3ABKA 3QJSA 2EIJA 2OCCA 3OMIA 4G7SA 3HB3A 1AR1A 5B1AA 5IY5A 3QJRA 3ASNA 4G7RA 4G71A 2EILA 4GP4A 2Y69A 3EH4A 1OCOA 4XYDA 3AG3A 1OCZA 3QJVA 1XMEA 4G72A 1V54A 3EH3A 2GSMA 4N4YA 1FFTA 2EINA 2DYRA 3S3CA 3BVDA 3WFDB 3S8GA 3WFCB 3FYEA 1OCCA 3FYIA 5DJQA 3X2QA 3S3BA 5B3SA 2EIMA 3MK7A 3WG7A 4G70A 5B1BA 3AYFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M56 A;  3OMA A;  3S8F A;  3EHB A;  3OMN A;  2ZXW A;  4FA7 A;  3WFE B;  3O0R B;  1OCR A;  3DTU A;  4FAA A;  2DYS A;  4G7Q A;  3ABM A;  3ASO A;  3EH5 A;  3AYG A;  3ABL A;  1V55 A;  3QJT A;  3QJQ A;  2EIK A;  3AG4 A;  2YEV A;  4GP8 A;  1M57 A;  3QJU A;  3S3D A;  3AG1 A;  1EHK A;  2QPE A;  3OM3 A;  1QLE A;  4GP5 A;  2QPD A;  3WFB B;  3AG2 A;  3ABK A;  3QJS A;  2EIJ A;  2OCC A;  3OMI A;  4G7S A;  3HB3 A;  1AR1 A;  5B1A A;  5IY5 A;  3QJR A;  3ASN A;  4G7R A;  4G71 A;  2EIL A;  4GP4 A;  2Y69 A;  3EH4 A;  1OCO A;  4XYD A;  3AG3 A;  1OCZ A;  3QJV A;  1XME A;  4G72 A;  1V54 A;  3EH3 A;  2GSM A;  4N4Y A;  1FFT A;  2EIN A;  2DYR A;  3S3C A;  3BVD A;  3WFD B;  3S8G A;  3WFC B;  3FYE A;  1OCC A;  3FYI A;  5DJQ A;  3X2Q A;  3S3B A;  5B3S A;  2EIM A;  3MK7 A;  3WG7 A;  4G70 A;  5B1B A;  3AYF A; 
#chains in the Genus database with same CATH topology
 1M56 A;  3OMA A;  3S8F A;  3EHB A;  3OMN A;  2ZXW A;  4FA7 A;  3WFE B;  3O0R B;  1OCR A;  3DTU A;  4FAA A;  2DYS A;  4G7Q A;  3ABM A;  3ASO A;  3EH5 A;  3AYG A;  3ABL A;  1V55 A;  3QJT A;  3QJQ A;  2EIK A;  3AG4 A;  2YEV A;  4GP8 A;  1M57 A;  3QJU A;  3S3D A;  3AG1 A;  1EHK A;  2QPE A;  3OM3 A;  1QLE A;  4GP5 A;  2QPD A;  3WFB B;  3AG2 A;  3ABK A;  3QJS A;  2EIJ A;  2OCC A;  3OMI A;  4G7S A;  3HB3 A;  1AR1 A;  5B1A A;  5IY5 A;  3QJR A;  3ASN A;  4G7R A;  4G71 A;  2EIL A;  4GP4 A;  2Y69 A;  3EH4 A;  1OCO A;  4XYD A;  3AG3 A;  1OCZ A;  3QJV A;  1XME A;  4G72 A;  1V54 A;  3EH3 A;  2GSM A;  4N4Y A;  1FFT A;  2EIN A;  2DYR A;  3S3C A;  3BVD A;  3WFD B;  3S8G A;  3WFC B;  3FYE A;  1OCC A;  3FYI A;  5DJQ A;  3X2Q A;  3S3B A;  5B3S A;  2EIM A;  3MK7 A;  3WG7 A;  4G70 A;  5B1B A;  3AYF A; 
#chains in the Genus database with same CATH homology
 1M56 A;  3OMA A;  3S8F A;  3EHB A;  3OMN A;  2ZXW A;  4FA7 A;  3WFE B;  3O0R B;  1OCR A;  3DTU A;  4FAA A;  2DYS A;  4G7Q A;  3ABM A;  3ASO A;  3EH5 A;  3AYG A;  3ABL A;  1V55 A;  3QJT A;  3QJQ A;  2EIK A;  3AG4 A;  2YEV A;  4GP8 A;  1M57 A;  3QJU A;  3S3D A;  3AG1 A;  1EHK A;  2QPE A;  3OM3 A;  1QLE A;  4GP5 A;  2QPD A;  3WFB B;  3AG2 A;  3ABK A;  3QJS A;  2EIJ A;  2OCC A;  3OMI A;  4G7S A;  3HB3 A;  1AR1 A;  5B1A A;  5IY5 A;  3QJR A;  3ASN A;  4G7R A;  4G71 A;  2EIL A;  4GP4 A;  2Y69 A;  3EH4 A;  1OCO A;  4XYD A;  3AG3 A;  1OCZ A;  3QJV A;  1XME A;  4G72 A;  1V54 A;  3EH3 A;  2GSM A;  4N4Y A;  1FFT A;  2EIN A;  2DYR A;  3S3C A;  3BVD A;  3WFD B;  3S8G A;  3WFC B;  3FYE A;  1OCC A;  3FYI A;  5DJQ A;  3X2Q A;  3S3B A;  5B3S A;  2EIM A;  3MK7 A;  3WG7 A;  4G70 A;  5B1B A;  3AYF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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