3FYIA

Catalytic core subunits (i and ii) of cytochrome c oxidase from rhodobacter sphaeroides in the reduced state bound with cyanide
Total Genus 229
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
229
sequence length
535
structure length
535
Chain Sequence
FTRWFMSTNHKDIGVLYLFTGGLVGLISVAFTVYMRMELMAPGVQFMCAEHLESGLVKGFFQSLWPSAVENCTPNGHLWNVMITGHGILMMFFVVIPALFGGFGNYFMPLHIGAPDMAFPRMNNLSYWLYVAGTSLAVASLFAPGGNGQLGSGIGWVLYPPLSTSESGYSTDLAIFAVHLSGASSILGAINMITTFLNMRAPGMTMHKVPLFAWSIFVTAWLILLALPVLAGAITMLLTDRNFGTTFFQPSGGGDPVLYQHILWFFGHPEVYIIVLPAFGIVSHVIATFAKKPIFGYLPMVYAMVAIGVLGFVVWAHHMYTAGLSLTQQSYFMMATMVIAVPTGIKIFSWIATMWGGSIELKTPMLWALGFLFLFTVGGVTGIVLSQASVDRYYHDTYYVVAHFHYVMSLGAVFGIFAGIYFWIGKMSGRQYPEWAGKLHFWMMFVGANLTFFPQHFLGRQGMPRRYIDYPEAFATWNFVSSLGAFLSFASFLFFLGVIFYTLTRGARVTANNYWNEHADTLEWTLTSPPPEHTF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Redox dependent conformational changes in cytochrome c oxidase suggest a gating mechanism for proton uptake.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Rhodobacter sphaeroides
molecule keywords Cytochrome c oxidase subunit 1
total genus 229
structure length 535
sequence length 535
chains with identical sequence C
ec nomenclature ec 1.9.3.1: Cytochrome-c oxidase.
pdb deposition date 2009-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00115 COX1 Cytochrome C and Quinol oxidase polypeptide I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase; Chain A Cytochrome c oxidase-like, subunit I domain 3fyiA00
5B1BA 2EIMA 3AYGA 3OMAA 4G70A 5DJQA 5IY5A 3DTUA 1QLEA 3QJRA 2YEVA 3AYFA 3QJSA 4GP4A 3WFDB 3WFCB 3BVDA 1FFTA 4XYDA 2Y69A 3WFBB 2EILA 3ABKA 4N4YA 3S3CA 1OCZA 4GP5A 1OCCA 1M57A 1EHKA 4G71A 3ABLA 3O0RB 3S8FA 1OCRA 2EIJA 2EINA 3S8GA 3X2QA 1XMEA 2ZXWA 3HB3A 3QJUA 3S3DA 4FA7A 2DYSA 3S3BA 2DYRA 1AR1A 3EH5A 3OMIA 4G7QA 3EHBA 3WFEB 3AG4A 5B3SA 1M56A 3OMNA 4G72A 1OCOA 3AG1A 3QJQA 2QPEA 5B1AA 4FAAA 3ABMA 3OM3A 2EIKA 4G7SA 3ASOA 3FYEA 3AG2A 3AG3A 3EH4A 2QPDA 3QJVA 4GP8A 1V55A 3FYIA 3WG7A 2GSMA 3EH3A 3ASNA 3MK7A 2OCCA 3QJTA 1V54A 4G7RA
chains in the Genus database with same CATH superfamily
5B1BA 2EIMA 3AYGA 3OMAA 4G70A 5DJQA 5IY5A 3DTUA 1QLEA 3QJRA 2YEVA 3AYFA 3QJSA 4GP4A 3WFDB 3WFCB 3BVDA 1FFTA 4XYDA 2Y69A 3WFBB 2EILA 3ABKA 4N4YA 3S3CA 1OCZA 4GP5A 1OCCA 1M57A 1EHKA 4G71A 3ABLA 3O0RB 3S8FA 1OCRA 2EIJA 2EINA 3S8GA 3X2QA 1XMEA 2ZXWA 3HB3A 3QJUA 3S3DA 4FA7A 2DYSA 3S3BA 2DYRA 1AR1A 3EH5A 3OMIA 4G7QA 3EHBA 3WFEB 3AG4A 5B3SA 1M56A 3OMNA 4G72A 1OCOA 3AG1A 3QJQA 2QPEA 5B1AA 4FAAA 3ABMA 3OM3A 2EIKA 4G7SA 3ASOA 3FYEA 3AG2A 3AG3A 3EH4A 2QPDA 3QJVA 4GP8A 1V55A 3FYIA 3WG7A 2GSMA 3EH3A 3ASNA 3MK7A 2OCCA 3QJTA 1V54A 4G7RA
chains in the Genus database with same CATH topology
5B1BA 2EIMA 3AYGA 3OMAA 4G70A 5DJQA 5IY5A 3DTUA 1QLEA 3QJRA 2YEVA 3AYFA 3QJSA 4GP4A 3WFDB 3WFCB 3BVDA 1FFTA 4XYDA 2Y69A 3WFBB 2EILA 3ABKA 4N4YA 3S3CA 1OCZA 4GP5A 1OCCA 1M57A 1EHKA 4G71A 3ABLA 3O0RB 3S8FA 1OCRA 2EIJA 2EINA 3S8GA 3X2QA 1XMEA 2ZXWA 3HB3A 3QJUA 3S3DA 4FA7A 2DYSA 3S3BA 2DYRA 1AR1A 3EH5A 3OMIA 4G7QA 3EHBA 3WFEB 3AG4A 5B3SA 1M56A 3OMNA 4G72A 1OCOA 3AG1A 3QJQA 2QPEA 5B1AA 4FAAA 3ABMA 3OM3A 2EIKA 4G7SA 3ASOA 3FYEA 3AG2A 3AG3A 3EH4A 2QPDA 3QJVA 4GP8A 1V55A 3FYIA 3WG7A 2GSMA 3EH3A 3ASNA 3MK7A 2OCCA 3QJTA 1V54A 4G7RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5B1B A;  2EIM A;  3AYG A;  3OMA A;  4G70 A;  5DJQ A;  5IY5 A;  3DTU A;  1QLE A;  3QJR A;  2YEV A;  3AYF A;  3QJS A;  4GP4 A;  3WFD B;  3WFC B;  3BVD A;  1FFT A;  4XYD A;  2Y69 A;  3WFB B;  2EIL A;  3ABK A;  4N4Y A;  3S3C A;  1OCZ A;  4GP5 A;  1OCC A;  1M57 A;  1EHK A;  4G71 A;  3ABL A;  3O0R B;  3S8F A;  1OCR A;  2EIJ A;  2EIN A;  3S8G A;  3X2Q A;  1XME A;  2ZXW A;  3HB3 A;  3QJU A;  3S3D A;  4FA7 A;  2DYS A;  3S3B A;  2DYR A;  1AR1 A;  3EH5 A;  3OMI A;  4G7Q A;  3EHB A;  3WFE B;  3AG4 A;  5B3S A;  1M56 A;  3OMN A;  4G72 A;  1OCO A;  3AG1 A;  3QJQ A;  2QPE A;  5B1A A;  4FAA A;  3ABM A;  3OM3 A;  2EIK A;  4G7S A;  3ASO A;  3FYE A;  3AG2 A;  3AG3 A;  3EH4 A;  2QPD A;  3QJV A;  4GP8 A;  1V55 A;  3FYI A;  3WG7 A;  2GSM A;  3EH3 A;  3ASN A;  3MK7 A;  2OCC A;  3QJT A;  1V54 A;  4G7R A; 
#chains in the Genus database with same CATH topology
 5B1B A;  2EIM A;  3AYG A;  3OMA A;  4G70 A;  5DJQ A;  5IY5 A;  3DTU A;  1QLE A;  3QJR A;  2YEV A;  3AYF A;  3QJS A;  4GP4 A;  3WFD B;  3WFC B;  3BVD A;  1FFT A;  4XYD A;  2Y69 A;  3WFB B;  2EIL A;  3ABK A;  4N4Y A;  3S3C A;  1OCZ A;  4GP5 A;  1OCC A;  1M57 A;  1EHK A;  4G71 A;  3ABL A;  3O0R B;  3S8F A;  1OCR A;  2EIJ A;  2EIN A;  3S8G A;  3X2Q A;  1XME A;  2ZXW A;  3HB3 A;  3QJU A;  3S3D A;  4FA7 A;  2DYS A;  3S3B A;  2DYR A;  1AR1 A;  3EH5 A;  3OMI A;  4G7Q A;  3EHB A;  3WFE B;  3AG4 A;  5B3S A;  1M56 A;  3OMN A;  4G72 A;  1OCO A;  3AG1 A;  3QJQ A;  2QPE A;  5B1A A;  4FAA A;  3ABM A;  3OM3 A;  2EIK A;  4G7S A;  3ASO A;  3FYE A;  3AG2 A;  3AG3 A;  3EH4 A;  2QPD A;  3QJV A;  4GP8 A;  1V55 A;  3FYI A;  3WG7 A;  2GSM A;  3EH3 A;  3ASN A;  3MK7 A;  2OCC A;  3QJT A;  1V54 A;  4G7R A; 
#chains in the Genus database with same CATH homology
 5B1B A;  2EIM A;  3AYG A;  3OMA A;  4G70 A;  5DJQ A;  5IY5 A;  3DTU A;  1QLE A;  3QJR A;  2YEV A;  3AYF A;  3QJS A;  4GP4 A;  3WFD B;  3WFC B;  3BVD A;  1FFT A;  4XYD A;  2Y69 A;  3WFB B;  2EIL A;  3ABK A;  4N4Y A;  3S3C A;  1OCZ A;  4GP5 A;  1OCC A;  1M57 A;  1EHK A;  4G71 A;  3ABL A;  3O0R B;  3S8F A;  1OCR A;  2EIJ A;  2EIN A;  3S8G A;  3X2Q A;  1XME A;  2ZXW A;  3HB3 A;  3QJU A;  3S3D A;  4FA7 A;  2DYS A;  3S3B A;  2DYR A;  1AR1 A;  3EH5 A;  3OMI A;  4G7Q A;  3EHB A;  3WFE B;  3AG4 A;  5B3S A;  1M56 A;  3OMN A;  4G72 A;  1OCO A;  3AG1 A;  3QJQ A;  2QPE A;  5B1A A;  4FAA A;  3ABM A;  3OM3 A;  2EIK A;  4G7S A;  3ASO A;  3FYE A;  3AG2 A;  3AG3 A;  3EH4 A;  2QPD A;  3QJV A;  4GP8 A;  1V55 A;  3FYI A;  3WG7 A;  2GSM A;  3EH3 A;  3ASN A;  3MK7 A;  2OCC A;  3QJT A;  1V54 A;  4G7R A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...