3OM3A

Catalytic core subunits (i and ii) of cytochrome c oxidase from rhodobacter sphaeroides with k362m mutation in the reduced state
Total Genus 230
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
230
sequence length
535
structure length
535
Chain Sequence
FTRWFMSTNHKDIGVLYLFTGGLVGLISVAFTVYMRMELMAPGVQFMCAEHLESGLVKGFFQSLWPSAVENCTPNGHLWNVMITGHGILMMFFVVIPALFGGFGNYFMPLHIGAPDMAFPRMNNLSYWLYVAGTSLAVASLFAPGGNGQLGSGIGWVLYPPLSTSESGYSTDLAIFAVHLSGASSILGAINMITTFLNMRAPGMTMHKVPLFAWSIFVTAWLILLALPVLAGAITMLLTDRNFGTTFFQPSGGGDPVLYQHILWFFGHPEVYIIVLPAFGIVSHVIATFAKKPIFGYLPMVYAMVAIGVLGFVVWAHHMYTAGLSLTQQSYFMMATMVIAVPTGIMIFSWIATMWGGSIELKTPMLWALGFLFLFTVGGVTGIVLSQASVDRYYHDTYYVVAHFHYVMSLGAVFGIFAGIYFWIGKMSGRQYPEWAGKLHFWMMFVGANLTFFPQHFLGRQGMPRRYIDYPEAFATWNFVSSLGAFLSFASFLFFLGVIFYTLTRGARVTANNYWNEHADTLEWTLTSPPPEHTF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pump.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Rhodobacter sphaeroides 2.4.1
molecule keywords Cytochrome c oxidase, aa3 type, subunit I
total genus 230
structure length 535
sequence length 535
chains with identical sequence C
ec nomenclature ec 1.9.3.1: Cytochrome-c oxidase.
pdb deposition date 2010-08-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00115 COX1 Cytochrome C and Quinol oxidase polypeptide I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase; Chain A Cytochrome c oxidase-like, subunit I domain 3om3A00
3WG7A 3AYGA 3ABMA 3EHBA 3FYEA 1OCZA 3ABLA 1AR1A 5IY5A 2EIMA 3AG1A 3QJQA 3O0RB 2DYSA 2QPEA 4G7RA 2EINA 4N4YA 4GP4A 3WFCB 1XMEA 4FAAA 1QLEA 1FFTA 1OCOA 4GP5A 5B1BA 3WFEB 4G71A 3ASOA 4G7SA 3EH4A 1V55A 3ABKA 3ASNA 1EHKA 2ZXWA 3QJTA 5DJQA 3OMNA 3OMAA 1M57A 2QPDA 2EIJA 1M56A 3QJSA 4G7QA 2YEVA 3AG3A 3EH3A 2Y69A 3QJVA 1OCRA 4GP8A 3DTUA 3QJRA 3OM3A 2EIKA 3S3CA 3AG4A 3OMIA 3S3BA 3MK7A 3AYFA 4FA7A 3WFDB 4XYDA 2DYRA 3HB3A 4G70A 3S8GA 5B1AA 3S8FA 3QJUA 3BVDA 3AG2A 1V54A 3X2QA 1OCCA 5B3SA 2EILA 3WFBB 3FYIA 3S3DA 3EH5A 2GSMA 4G72A 2OCCA
chains in the Genus database with same CATH superfamily
3WG7A 3AYGA 3ABMA 3EHBA 3FYEA 1OCZA 3ABLA 1AR1A 5IY5A 2EIMA 3AG1A 3QJQA 3O0RB 2DYSA 2QPEA 4G7RA 2EINA 4N4YA 4GP4A 3WFCB 1XMEA 4FAAA 1QLEA 1FFTA 1OCOA 4GP5A 5B1BA 3WFEB 4G71A 3ASOA 4G7SA 3EH4A 1V55A 3ABKA 3ASNA 1EHKA 2ZXWA 3QJTA 5DJQA 3OMNA 3OMAA 1M57A 2QPDA 2EIJA 1M56A 3QJSA 4G7QA 2YEVA 3AG3A 3EH3A 2Y69A 3QJVA 1OCRA 4GP8A 3DTUA 3QJRA 3OM3A 2EIKA 3S3CA 3AG4A 3OMIA 3S3BA 3MK7A 3AYFA 4FA7A 3WFDB 4XYDA 2DYRA 3HB3A 4G70A 3S8GA 5B1AA 3S8FA 3QJUA 3BVDA 3AG2A 1V54A 3X2QA 1OCCA 5B3SA 2EILA 3WFBB 3FYIA 3S3DA 3EH5A 2GSMA 4G72A 2OCCA
chains in the Genus database with same CATH topology
3WG7A 3AYGA 3ABMA 3EHBA 3FYEA 1OCZA 3ABLA 1AR1A 5IY5A 2EIMA 3AG1A 3QJQA 3O0RB 2DYSA 2QPEA 4G7RA 2EINA 4N4YA 4GP4A 3WFCB 1XMEA 4FAAA 1QLEA 1FFTA 1OCOA 4GP5A 5B1BA 3WFEB 4G71A 3ASOA 4G7SA 3EH4A 1V55A 3ABKA 3ASNA 1EHKA 2ZXWA 3QJTA 5DJQA 3OMNA 3OMAA 1M57A 2QPDA 2EIJA 1M56A 3QJSA 4G7QA 2YEVA 3AG3A 3EH3A 2Y69A 3QJVA 1OCRA 4GP8A 3DTUA 3QJRA 3OM3A 2EIKA 3S3CA 3AG4A 3OMIA 3S3BA 3MK7A 3AYFA 4FA7A 3WFDB 4XYDA 2DYRA 3HB3A 4G70A 3S8GA 5B1AA 3S8FA 3QJUA 3BVDA 3AG2A 1V54A 3X2QA 1OCCA 5B3SA 2EILA 3WFBB 3FYIA 3S3DA 3EH5A 2GSMA 4G72A 2OCCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WG7 A;  3AYG A;  3ABM A;  3EHB A;  3FYE A;  1OCZ A;  3ABL A;  1AR1 A;  5IY5 A;  2EIM A;  3AG1 A;  3QJQ A;  3O0R B;  2DYS A;  2QPE A;  4G7R A;  2EIN A;  4N4Y A;  4GP4 A;  3WFC B;  1XME A;  4FAA A;  1QLE A;  1FFT A;  1OCO A;  4GP5 A;  5B1B A;  3WFE B;  4G71 A;  3ASO A;  4G7S A;  3EH4 A;  1V55 A;  3ABK A;  3ASN A;  1EHK A;  2ZXW A;  3QJT A;  5DJQ A;  3OMN A;  3OMA A;  1M57 A;  2QPD A;  2EIJ A;  1M56 A;  3QJS A;  4G7Q A;  2YEV A;  3AG3 A;  3EH3 A;  2Y69 A;  3QJV A;  1OCR A;  4GP8 A;  3DTU A;  3QJR A;  3OM3 A;  2EIK A;  3S3C A;  3AG4 A;  3OMI A;  3S3B A;  3MK7 A;  3AYF A;  4FA7 A;  3WFD B;  4XYD A;  2DYR A;  3HB3 A;  4G70 A;  3S8G A;  5B1A A;  3S8F A;  3QJU A;  3BVD A;  3AG2 A;  1V54 A;  3X2Q A;  1OCC A;  5B3S A;  2EIL A;  3WFB B;  3FYI A;  3S3D A;  3EH5 A;  2GSM A;  4G72 A;  2OCC A; 
#chains in the Genus database with same CATH topology
 3WG7 A;  3AYG A;  3ABM A;  3EHB A;  3FYE A;  1OCZ A;  3ABL A;  1AR1 A;  5IY5 A;  2EIM A;  3AG1 A;  3QJQ A;  3O0R B;  2DYS A;  2QPE A;  4G7R A;  2EIN A;  4N4Y A;  4GP4 A;  3WFC B;  1XME A;  4FAA A;  1QLE A;  1FFT A;  1OCO A;  4GP5 A;  5B1B A;  3WFE B;  4G71 A;  3ASO A;  4G7S A;  3EH4 A;  1V55 A;  3ABK A;  3ASN A;  1EHK A;  2ZXW A;  3QJT A;  5DJQ A;  3OMN A;  3OMA A;  1M57 A;  2QPD A;  2EIJ A;  1M56 A;  3QJS A;  4G7Q A;  2YEV A;  3AG3 A;  3EH3 A;  2Y69 A;  3QJV A;  1OCR A;  4GP8 A;  3DTU A;  3QJR A;  3OM3 A;  2EIK A;  3S3C A;  3AG4 A;  3OMI A;  3S3B A;  3MK7 A;  3AYF A;  4FA7 A;  3WFD B;  4XYD A;  2DYR A;  3HB3 A;  4G70 A;  3S8G A;  5B1A A;  3S8F A;  3QJU A;  3BVD A;  3AG2 A;  1V54 A;  3X2Q A;  1OCC A;  5B3S A;  2EIL A;  3WFB B;  3FYI A;  3S3D A;  3EH5 A;  2GSM A;  4G72 A;  2OCC A; 
#chains in the Genus database with same CATH homology
 3WG7 A;  3AYG A;  3ABM A;  3EHB A;  3FYE A;  1OCZ A;  3ABL A;  1AR1 A;  5IY5 A;  2EIM A;  3AG1 A;  3QJQ A;  3O0R B;  2DYS A;  2QPE A;  4G7R A;  2EIN A;  4N4Y A;  4GP4 A;  3WFC B;  1XME A;  4FAA A;  1QLE A;  1FFT A;  1OCO A;  4GP5 A;  5B1B A;  3WFE B;  4G71 A;  3ASO A;  4G7S A;  3EH4 A;  1V55 A;  3ABK A;  3ASN A;  1EHK A;  2ZXW A;  3QJT A;  5DJQ A;  3OMN A;  3OMA A;  1M57 A;  2QPD A;  2EIJ A;  1M56 A;  3QJS A;  4G7Q A;  2YEV A;  3AG3 A;  3EH3 A;  2Y69 A;  3QJV A;  1OCR A;  4GP8 A;  3DTU A;  3QJR A;  3OM3 A;  2EIK A;  3S3C A;  3AG4 A;  3OMI A;  3S3B A;  3MK7 A;  3AYF A;  4FA7 A;  3WFD B;  4XYD A;  2DYR A;  3HB3 A;  4G70 A;  3S8G A;  5B1A A;  3S8F A;  3QJU A;  3BVD A;  3AG2 A;  1V54 A;  3X2Q A;  1OCC A;  5B3S A;  2EIL A;  3WFB B;  3FYI A;  3S3D A;  3EH5 A;  2GSM A;  4G72 A;  2OCC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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