4TZLA

Structure of c. elegans htp-2 bound to him-3 closure motif, p21 form
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
235
structure length
228
Chain Sequence
DAIDDKTWSKLFPSIVSDPDRSSNFMIRAIYVVFSAVLRQRNILEKEYFSKNYITENLSCMTLSFKNLRAHQIAQLLRAAGDATKDGFLKEISLVVTEHDGDVEAIEVFSMKFIYFENGGVVARLEDPHFAELAQLRYEGAESVRDQMVTIVRSVQFLCTKVLEPLPAEFTANFRLKYTNDAPSNFRIDGFDDSSTFYTLPDGIQSVTIGHLRPGHHAAHMQCWSKSM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Chromosome Axis Controls Meiotic Events through a Hierarchical Assembly of HORMA Domain Proteins.
pubmed doi rcsb
molecule tags Peptide binding protein
source organism Caenorhabditis elegans
molecule keywords Protein HTP-2
total genus 60
structure length 228
sequence length 235
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-07-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02301 HORMA HORMA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.900.10 Alpha Beta 2-Layer Sandwich Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A HORMA domain 4tzlA00
4FJOC 4EXTC 1DUJA 4TZOA 4J2GA 2V64D 4AEZB 3ABEC 4TZNA 4TZQA 4TZLA 1S2HA 3ABDA 4TRKA 4TZMA 2VFXA 1KLQA 5LCWZ 3GMHA 4GK5A 2QYFA 1GO4A 4TZJA 5C50B 4YK8B 4GK0A 4TZSA 2V64A 3VU7C
chains in the Genus database with same CATH superfamily
4FJOC 4EXTC 1DUJA 4TZOA 2QYFB 4J2GA 2V64D 4AEZB 3ABEC 4TZNA 4TZQA 4TZLA 1S2HA 3ABDA 4TRKA 4TZMA 2VFXA 1KLQA 5LCWZ 3GMHA 4GK5A 2QYFA 1GO4A 4TZJA 5C50B 4YK8B 4GK0A 4TZSA 2V64A 3VU7C
chains in the Genus database with same CATH topology
4FJOC 4EXTC 1DUJA 4TZOA 4J2GA 2V64D 4AEZB 3ABEC 4TZNA 4TZQA 4TZLA 1S2HA 3ABDA 4TRKA 4TZMA 2VFXA 1KLQA 5LCWZ 3GMHA 4GK5A 2QYFA 1GO4A 4TZJA 5C50B 4YK8B 4GK0A 4TZSA 2V64A 3VU7C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FJO C;  4EXT C;  1DUJ A;  4TZO A;  4J2G A;  2V64 D;  4AEZ B;  3ABE C;  4TZN A;  4TZQ A;  4TZL A;  1S2H A;  3ABD A;  4TRK A;  4TZM A;  2VFX A;  1KLQ A;  5LCW Z;  3GMH A;  4GK5 A;  2QYF A;  1GO4 A;  4TZJ A;  5C50 B;  4YK8 B;  4GK0 A;  4TZS A;  2V64 A;  3VU7 C; 
#chains in the Genus database with same CATH topology
 4FJO C;  4EXT C;  1DUJ A;  4TZO A;  2QYF B;  4J2G A;  2V64 D;  4AEZ B;  3ABE C;  4TZN A;  4TZQ A;  4TZL A;  1S2H A;  3ABD A;  4TRK A;  4TZM A;  2VFX A;  1KLQ A;  5LCW Z;  3GMH A;  4GK5 A;  2QYF A;  1GO4 A;  4TZJ A;  5C50 B;  4YK8 B;  4GK0 A;  4TZS A;  2V64 A;  3VU7 C; 
#chains in the Genus database with same CATH homology
 4FJO C;  4EXT C;  1DUJ A;  4TZO A;  4J2G A;  2V64 D;  4AEZ B;  3ABE C;  4TZN A;  4TZQ A;  4TZL A;  1S2H A;  3ABD A;  4TRK A;  4TZM A;  2VFX A;  1KLQ A;  5LCW Z;  3GMH A;  4GK5 A;  2QYF A;  1GO4 A;  4TZJ A;  5C50 B;  4YK8 B;  4GK0 A;  4TZS A;  2V64 A;  3VU7 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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