4TZLA

Structure of c. elegans htp-2 bound to him-3 closure motif, p21 form
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
235
structure length
228
Chain Sequence
DAIDDKTWSKLFPSIVSDPDRSSNFMIRAIYVVFSAVLRQRNILEKEYFSKNYITENLSCMTLSFKNLRAHQIAQLLRAAGDATKDGFLKEISLVVTEHDGDVEAIEVFSMKFIYFENGGVVARLEDPHFAELAQLRYEGAESVRDQMVTIVRSVQFLCTKVLEPLPAEFTANFRLKYTNDAPSNFRIDGFDDSSTFYTLPDGIQSVTIGHLRPGHHAAHMQCWSKSM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Chromosome Axis Controls Meiotic Events through a Hierarchical Assembly of HORMA Domain Proteins.
pubmed doi rcsb
molecule keywords Protein HTP-2
molecule tags Peptide binding protein
source organism Caenorhabditis elegans
total genus 60
structure length 228
sequence length 235
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-07-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02301 HORMA HORMA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.900.10 Alpha Beta 2-Layer Sandwich Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A HORMA domain 4tzlA00
4TZQA 4TZLA 4GK0A 5C50B 1GO4A 4TZJA 4GK5A 2V64A 4AEZB 4TZMA 4TZSA 4EXTC 4TZNA 1DUJA 3VU7C 1S2HA 4J2GA 2QYFA 3GMHA 5LCWZ 4YK8B 4TZOA 3ABDA 2V64D 3ABEC 2VFXA 4FJOC 4TRKA 1KLQA
chains in the Genus database with same CATH superfamily
4TZQA 4TZLA 4GK0A 5C50B 1GO4A 4TZJA 4GK5A 2V64A 4AEZB 4TZMA 4TZSA 4EXTC 4TZNA 1DUJA 3VU7C 1S2HA 4J2GA 2QYFA 3GMHA 5LCWZ 4YK8B 4TZOA 3ABDA 2QYFB 2V64D 3ABEC 2VFXA 4FJOC 4TRKA 1KLQA
chains in the Genus database with same CATH topology
4TZQA 4TZLA 4GK0A 5C50B 1GO4A 4TZJA 4GK5A 2V64A 4AEZB 4TZMA 4TZSA 4EXTC 4TZNA 1DUJA 3VU7C 1S2HA 4J2GA 2QYFA 3GMHA 5LCWZ 4YK8B 4TZOA 3ABDA 2V64D 3ABEC 2VFXA 4FJOC 4TRKA 1KLQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TZQ A;  4TZL A;  4GK0 A;  5C50 B;  1GO4 A;  4TZJ A;  4GK5 A;  2V64 A;  4AEZ B;  4TZM A;  4TZS A;  4EXT C;  4TZN A;  1DUJ A;  3VU7 C;  1S2H A;  4J2G A;  2QYF A;  3GMH A;  5LCW Z;  4YK8 B;  4TZO A;  3ABD A;  2V64 D;  3ABE C;  2VFX A;  4FJO C;  4TRK A;  1KLQ A; 
#chains in the Genus database with same CATH topology
 4TZQ A;  4TZL A;  4GK0 A;  5C50 B;  1GO4 A;  4TZJ A;  4GK5 A;  2V64 A;  4AEZ B;  4TZM A;  4TZS A;  4EXT C;  4TZN A;  1DUJ A;  3VU7 C;  1S2H A;  4J2G A;  2QYF A;  3GMH A;  5LCW Z;  4YK8 B;  4TZO A;  3ABD A;  2QYF B;  2V64 D;  3ABE C;  2VFX A;  4FJO C;  4TRK A;  1KLQ A; 
#chains in the Genus database with same CATH homology
 4TZQ A;  4TZL A;  4GK0 A;  5C50 B;  1GO4 A;  4TZJ A;  4GK5 A;  2V64 A;  4AEZ B;  4TZM A;  4TZS A;  4EXT C;  4TZN A;  1DUJ A;  3VU7 C;  1S2H A;  4J2G A;  2QYF A;  3GMH A;  5LCW Z;  4YK8 B;  4TZO A;  3ABD A;  2V64 D;  3ABE C;  2VFX A;  4FJO C;  4TRK A;  1KLQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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