4U3FI

Cytochrome bc1 complex from chicken with designed inhibitor bound
Total Genus 0
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
0
sequence length
47
structure length
44
Chain Sequence
XXXXXXXXXXXXXXPLLCRESMSGRSARRDLVAGISLNAPASVR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Rational Design of Highly Potent and Slow-Binding Cytochrome bc1 Inhibitor as Fungicide by Computational Substitution Optimization
doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Mitochondrial ubiquinol-cytochrome-c reductase complex core
structure length 44
sequence length 47
chains with identical sequence V
ec nomenclature ec 7.1.1.8: Quinol--cytochrome-c reductase.
pdb deposition date 2014-07-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF09165 Ubiq-Cytc-red_N Ubiquinol-cytochrome c reductase 8 kDa, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.210.10 Mainly Beta Ribbon Cytochrome Bc1 Complex; Chain I Cytochrome Bc1 Complex; Chain I 4u3fI00
1SQXI 3TGUI 3CWBI 1L0LI 1NU1I 1SQBI 3L73I 3L74I 3H1LI 3H1JI 3H1KI 1SQVI 4U3FI 1NTMI 1NTZI 1PP9I 3L75I 1PPJI 1SQPI 3L71I 1L0NI 3H1II 2A06I 3H1HI 3L72I 2FYUI 1NTKI 3L70I 1SQQI
chains in the Genus database with same CATH superfamily
1SQXI 3TGUI 3CWBI 1L0LI 1NU1I 1SQBI 3L73I 3L74I 3H1LI 3H1JI 3H1KI 1SQVI 4U3FI 1NTMI 1NTZI 1PP9I 3L75I 1PPJI 1SQPI 3L71I 1L0NI 3H1II 2A06I 3H1HI 3L72I 2FYUI 1NTKI 3L70I 1SQQI
chains in the Genus database with same CATH topology
1SQXI 3TGUI 3CWBI 1L0LI 1NU1I 1SQBI 3L73I 3L74I 3H1LI 3H1JI 3H1KI 1SQVI 4U3FI 1NTMI 1NTZI 1PP9I 3L75I 1PPJI 1SQPI 3L71I 1L0NI 3H1II 2A06I 3H1HI 3L72I 2FYUI 1NTKI 3L70I 1SQQI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SQX I;  3TGU I;  3CWB I;  1L0L I;  1NU1 I;  1SQB I;  3L73 I;  3L74 I;  3H1L I;  3H1J I;  3H1K I;  1SQV I;  4U3F I;  1NTM I;  1NTZ I;  1PP9 I;  3L75 I;  1PPJ I;  1SQP I;  3L71 I;  1L0N I;  3H1I I;  2A06 I;  3H1H I;  3L72 I;  2FYU I;  1NTK I;  3L70 I;  1SQQ I; 
#chains in the Genus database with same CATH topology
 1SQX I;  3TGU I;  3CWB I;  1L0L I;  1NU1 I;  1SQB I;  3L73 I;  3L74 I;  3H1L I;  3H1J I;  3H1K I;  1SQV I;  4U3F I;  1NTM I;  1NTZ I;  1PP9 I;  3L75 I;  1PPJ I;  1SQP I;  3L71 I;  1L0N I;  3H1I I;  2A06 I;  3H1H I;  3L72 I;  2FYU I;  1NTK I;  3L70 I;  1SQQ I; 
#chains in the Genus database with same CATH homology
 1SQX I;  3TGU I;  3CWB I;  1L0L I;  1NU1 I;  1SQB I;  3L73 I;  3L74 I;  3H1L I;  3H1J I;  3H1K I;  1SQV I;  4U3F I;  1NTM I;  1NTZ I;  1PP9 I;  3L75 I;  1PPJ I;  1SQP I;  3L71 I;  1L0N I;  3H1I I;  2A06 I;  3H1H I;  3L72 I;  2FYU I;  1NTK I;  3L70 I;  1SQQ I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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