4EXT | Genus

Total Genus 52

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	52
sequence length	204
structure length	198
Chain Sequence	TQDLNFGQVVADVLCEFLEVAVHLILYVREVYPVGIFQKRKKYNVPVQMSCHPELNQYIQDTLHCVKPLLEKNDVEKVVVVILDKEHRPVEKFVFEITQPSDSLLSHVEQLLRAFILKISVCDAVLDHNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILADEQDVHMHDPRLIPLKTMTSDILKMQLYVEERAHK

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 198 atoms

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198 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase/transcription
source organism	Homo sapiens
publication title	Insights into the scaffold mechanism of human Rev1 in translesional synthesis revealed by structural studies on its polymerase-interacting domain rcsb
molecule keywords	DNA repair protein REV1
total genus	52
structure length	198
sequence length	204
ec nomenclature
pdb deposition date	2012-05-01

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
C	PF02301	HORMA	HORMA domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.900.10	Alpha Beta	2-Layer Sandwich	Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A	HORMA domain	4extC00

4EXTC 3ABDA 5LCWZ 4TZMA 4TZOA 2QYFA 2VFXA 4TZLA 3VU7C 4J2GA 4TZJA 4FJOC 4YK8B 1S2HA 2V64A 4TZQA 2V64D 1GO4A 5C50B 4TZSA 4AEZB 4GK0A 4GK5A 3ABEC 3GMHA 1KLQA 4TRKA 1DUJA 4TZNA
chains in the Genus database with same CATH superfamily

2QYFB 4EXTC 3ABDA 5LCWZ 4TZMA 4TZOA 2QYFA 2VFXA 4TZLA 3VU7C 4J2GA 4TZJA 4FJOC 4YK8B 1S2HA 2V64A 4TZQA 2V64D 1GO4A 5C50B 4TZSA 4AEZB 4GK0A 4GK5A 3ABEC 3GMHA 1KLQA 4TRKA 1DUJA 4TZNA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4EXT C;  3ABD A;  5LCW Z;  4TZM A;  4TZO A;  2QYF A;  2VFX A;  4TZL A;  3VU7 C;  4J2G A;  4TZJ A;  4FJO C;  4YK8 B;  1S2H A;  2V64 A;  4TZQ A;  2V64 D;  1GO4 A;  5C50 B;  4TZS A;  4AEZ B;  4GK0 A;  4GK5 A;  3ABE C;  3GMH A;  1KLQ A;  4TRK A;  1DUJ A;  4TZN A; 
#chains in the Genus database with same CATH topology
 2QYF B;  4EXT C;  3ABD A;  5LCW Z;  4TZM A;  4TZO A;  2QYF A;  2VFX A;  4TZL A;  3VU7 C;  4J2G A;  4TZJ A;  4FJO C;  4YK8 B;  1S2H A;  2V64 A;  4TZQ A;  2V64 D;  1GO4 A;  5C50 B;  4TZS A;  4AEZ B;  4GK0 A;  4GK5 A;  3ABE C;  3GMH A;  1KLQ A;  4TRK A;  1DUJ A;  4TZN A; 
#chains in the Genus database with same CATH homology
 4EXT C;  3ABD A;  5LCW Z;  4TZM A;  4TZO A;  2QYF A;  2VFX A;  4TZL A;  3VU7 C;  4J2G A;  4TZJ A;  4FJO C;  4YK8 B;  1S2H A;  2V64 A;  4TZQ A;  2V64 D;  1GO4 A;  5C50 B;  4TZS A;  4AEZ B;  4GK0 A;  4GK5 A;  3ABE C;  3GMH A;  1KLQ A;  4TRK A;  1DUJ A;  4TZN A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4EXTC

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations