The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
315
|
sequence length |
1006
|
structure length |
965
|
Chain Sequence |
AACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILQHTVLCGSQYPCRDPFFMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSFQIEPSTVVPAQTPWDKPREFQITCGPDPSKQTTVSVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIVEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQVEALSPGDRQQIYEGLELRSQQSKPQDASLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTLGCGLLDYREQAQQIELTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRLPRIKHLLNGDNMRCSVNATPQQMPQTEAVEDFLRSIGRSKKERRPVRPHTVEKPVPVIRKLVMEPTFKPWQMTHFLMPFPVNYVGECIRTVPYTDPDHASLILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGAVDWASGFTQQDIDEAKLSVFSTVDAPVAPSDGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIR
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| molecule tags |
Hydrolase/protein binding
|
| molecule keywords |
Presequence protease, mitochondrial
|
| publication title |
Molecular basis of substrate recognition and degradation by human presequence protease.
pubmed doi rcsb |
| source organism |
Homo sapiens
|
| total genus |
315
|
| structure length |
965
|
| sequence length |
1006
|
| ec nomenclature | |
| pdb deposition date | 2013-11-01 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| D | PF00675 | Peptidase_M16 | Insulinase (Peptidase family M16) |
| D | PF05193 | Peptidase_M16_C | Peptidase M16 inactive domain |
| D | PF08367 | M16C_assoc | Peptidase M16C associated |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 2-Layer Sandwich | Cytochrome Bc1 Complex; Chain A, domain 1 | Metalloenzyme, LuxS/M16 peptidase-like | ||
| Alpha Beta | 2-Layer Sandwich | Cytochrome Bc1 Complex; Chain A, domain 1 | Metalloenzyme, LuxS/M16 peptidase-like | ||
| Alpha Beta | 2-Layer Sandwich | Cytochrome Bc1 Complex; Chain A, domain 1 | Metalloenzyme, LuxS/M16 peptidase-like | ||
| Alpha Beta | 2-Layer Sandwich | Cytochrome Bc1 Complex; Chain A, domain 1 | Metalloenzyme, LuxS/M16 peptidase-like |
#chains in the Genus database with same CATH superfamily 4IFH A; 3H1H A; 2G49 A; 1L0N B; 3L74 A; 1KB9 A; 4QIA A; 3D3Y A; 1HR6 B; 3L73 B; 4NGE A; 1SQV B; 1SQQ A; 1BE3 B; 3P7O A; 1PP9 A; 2YPU A; 3H1J A; 3CX5 A; 4GSC A; 2FYU A; 3P7L A; 1NTZ B; 2IBZ A; 4IOF A; 3AMJ A; 1BGY B; 2A06 B; 3HGZ A; 3L71 A; 4LTE A; 2BCC B; 3GO9 A; 1L0L A; 1SQX B; 1KYO B; 1SQB A; 5CJO A; 5KLV A; 4PD4 A; 3H1I A; 3BCC A; 4L3T B; 1NU1 A; 4RPU B; 2G54 A; 3CWB B; 1BCC A; 1HR8 A; 1HR9 A; 1NTM B; 4D6T B; 4GS8 A; 3TGU B; 3L72 B; 1P84 B; 3CXH A; 3H1H B; 4PES A; 1KB9 B; 1SQP A; 4NGE D; 5EUF A; 3E50 A; 3L75 B; 2JBU A; 4NXO A; 1BE3 A; 1EZV A; 1SQQ B; 1Q2L A; 3AMI A; 4GSF A; 3H1L A; 1PP9 B; 4XEA A; 3CX5 B; 2FYU B; 3L70 A; 2WK3 A; 4PF7 A; 1BGY A; 1PPJ A; 2A06 A; 4U3F A; 1HR7 A; 1NTK A; 2BCC A; 4DWK A; 3HDI A; 2G47 A; 3H44 A; 3E4A A; 1KYO A; 1L0L B; 3CWW A; 3H1K B; 2FGE A; 2JG4 A; 1SQB B; 4PD4 B; 3H1I B; 1L0N A; 3BCC B; 4RAL A; 1NTM A; 3TGU A; 4M1C A; 4D6T A; 3L74 B; 1HR6 A; 3L72 A; 1BCC B; 1HR8 B; 1HR9 B; 3L73 A; 4NNZ A; 1SQV A; 3EOQ A; 3GWB A; 3N56 A; 4PF9 A; 3H1J B; 3TUV A; 2G56 A; 3CXH B; 1NTZ A; 2WC0 A; 2IBZ B; 3L75 A; 1SQP B; 3AMJ B; 3L71 B; 3IH6 A; 1EZV B; 1SQX A; 3QZ2 A; 4RE9 A; 3H1L B; 2G48 A; 4PFC A; 3E4Z A; 3IVL A; 3L70 B; 5KLV B; 2WBY A; 4L3T A; 1PPJ B; 4U3F B; 4DTT A; 4RPU A; 1HR7 B; 1NTK B; 3CWB A; 1NU1 B; 3OFI A; 1P84 A; 3H1K A; 4D6T O; 3N57 A; #chains in the Genus database with same CATH topology 4IFH A; 3H1H A; 2G49 A; 1L0N B; 3L74 A; 1KB9 A; 4QIA A; 3D3Y A; 1HR6 B; 3L73 B; 4NGE A; 1SQV B; 1SQQ A; 1BE3 B; 3P7O A; 1PP9 A; 2YPU A; 3H1J A; 3CX5 A; 4GSC A; 2FYU A; 3P7L A; 1NTZ B; 2IBZ A; 4IOF A; 3AMJ A; 1BGY B; 2A06 B; 3HGZ A; 3L71 A; 4LTE A; 2BCC B; 3GO9 A; 1L0L A; 1SQX B; 1KYO B; 1SQB A; 5CJO A; 5KLV A; 4PD4 A; 3H1I A; 3BCC A; 4L3T B; 1NU1 A; 4RPU B; 2G54 A; 3CWB B; 1BCC A; 1HR8 A; 1HR9 A; 1NTM B; 4D6T B; 4GS8 A; 3TGU B; 3L72 B; 1P84 B; 3CXH A; 3H1H B; 4PES A; 1KB9 B; 1SQP A; 4NGE D; 5EUF A; 3E50 A; 3L75 B; 2JBU A; 4NXO A; 1BE3 A; 1EZV A; 1SQQ B; 1Q2L A; 3AMI A; 4GSF A; 3H1L A; 1PP9 B; 4XEA A; 3CX5 B; 2FYU B; 3L70 A; 2WK3 A; 4PF7 A; 1BGY A; 1PPJ A; 2A06 A; 4U3F A; 1HR7 A; 1NTK A; 2BCC A; 4DWK A; 3HDI A; 2G47 A; 3H44 A; 3E4A A; 1KYO A; 1L0L B; 3CWW A; 3H1K B; 2FGE A; 2JG4 A; 1SQB B; 4PD4 B; 3H1I B; 1L0N A; 3BCC B; 4RAL A; 1NTM A; 3TGU A; 4M1C A; 4D6T A; 3L74 B; 1HR6 A; 3L72 A; 1BCC B; 1HR8 B; 1HR9 B; 3L73 A; 4NNZ A; 1SQV A; 3EOQ A; 3GWB A; 3N56 A; 4PF9 A; 3H1J B; 3TUV A; 2G56 A; 3CXH B; 1NTZ A; 2WC0 A; 2IBZ B; 3L75 A; 1SQP B; 3AMJ B; 3L71 B; 3IH6 A; 1EZV B; 1SQX A; 3QZ2 A; 4RE9 A; 3H1L B; 2G48 A; 4PFC A; 3E4Z A; 3IVL A; 3L70 B; 5KLV B; 2WBY A; 4L3T A; 1PPJ B; 4U3F B; 4DTT A; 4RPU A; 1HR7 B; 1NTK B; 3CWB A; 1NU1 B; 3OFI A; 1P84 A; 3H1K A; 4D6T O; 3N57 A; #chains in the Genus database with same CATH homology 4IFH A; 3H1H A; 2G49 A; 1L0N B; 3L74 A; 1KB9 A; 4QIA A; 3D3Y A; 1HR6 B; 3L73 B; 4NGE A; 1SQV B; 1SQQ A; 1BE3 B; 3P7O A; 1PP9 A; 2YPU A; 3H1J A; 3CX5 A; 4GSC A; 2FYU A; 3P7L A; 1NTZ B; 2IBZ A; 4IOF A; 3AMJ A; 1BGY B; 2A06 B; 3HGZ A; 3L71 A; 4LTE A; 2BCC B; 3GO9 A; 1L0L A; 1SQX B; 1KYO B; 1SQB A; 5CJO A; 5KLV A; 4PD4 A; 3H1I A; 3BCC A; 4L3T B; 1NU1 A; 4RPU B; 2G54 A; 3CWB B; 1BCC A; 1HR8 A; 1HR9 A; 1NTM B; 4D6T B; 4GS8 A; 3TGU B; 3L72 B; 1P84 B; 3CXH A; 3H1H B; 4PES A; 1KB9 B; 1SQP A; 4NGE D; 5EUF A; 3E50 A; 3L75 B; 2JBU A; 4NXO A; 1BE3 A; 1EZV A; 1SQQ B; 1Q2L A; 3AMI A; 4GSF A; 3H1L A; 1PP9 B; 4XEA A; 3CX5 B; 2FYU B; 3L70 A; 2WK3 A; 4PF7 A; 1BGY A; 1PPJ A; 2A06 A; 4U3F A; 1HR7 A; 1NTK A; 2BCC A; 4DWK A; 3HDI A; 2G47 A; 3H44 A; 3E4A A; 1KYO A; 1L0L B; 3CWW A; 3H1K B; 2FGE A; 2JG4 A; 1SQB B; 4PD4 B; 3H1I B; 1L0N A; 3BCC B; 4RAL A; 1NTM A; 3TGU A; 4M1C A; 4D6T A; 3L74 B; 1HR6 A; 3L72 A; 1BCC B; 1HR8 B; 1HR9 B; 3L73 A; 4NNZ A; 1SQV A; 3EOQ A; 3GWB A; 3N56 A; 4PF9 A; 3H1J B; 3TUV A; 2G56 A; 3CXH B; 1NTZ A; 2WC0 A; 2IBZ B; 3L75 A; 1SQP B; 3AMJ B; 3L71 B; 3IH6 A; 1EZV B; 1SQX A; 3QZ2 A; 4RE9 A; 3H1L B; 2G48 A; 4PFC A; 3E4Z A; 3IVL A; 3L70 B; 5KLV B; 2WBY A; 4L3T A; 1PPJ B; 4U3F B; 4DTT A; 4RPU A; 1HR7 B; 1NTK B; 3CWB A; 1NU1 B; 3OFI A; 1P84 A; 3H1K A; 4D6T O; 3N57 A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
