5B1AA

Bovine heart cytochrome c oxidase in the fully oxidized state at 1.5 angstrom resolution
Total Genus 207
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
207
sequence length
513
structure length
513
Chain Sequence
FINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Mg2+-containing Water Cluster of Mammalian Cytochrome c Oxidase Collects Four Pumping Proton Equivalents in Each Catalytic Cycle.
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Cytochrome c oxidase subunit 1
total genus 207
structure length 513
sequence length 513
chains with identical sequence N
ec nomenclature ec 1.9.3.1: Cytochrome-c oxidase.
pdb deposition date 2015-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00115 COX1 Cytochrome C and Quinol oxidase polypeptide I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase; Chain A Cytochrome c oxidase-like, subunit I domain 5b1aA00
3QJUA 2DYSA 3O0RB 3AYGA 1XMEA 3AG4A 1QLEA 3BVDA 1OCRA 2YEVA 3S8GA 2Y69A 2EIJA 3QJVA 3HB3A 3QJSA 1OCZA 3MK7A 3EH5A 3AG2A 3OMNA 3WFCB 3ASNA 2EILA 3WG7A 4G7QA 4FAAA 1OCOA 2EIMA 3AYFA 3ABMA 1V54A 5B1AA 2OCCA 3WFDB 3EH3A 3FYEA 3X2QA 2DYRA 2QPEA 5IY5A 1M56A 3S8FA 3WFEB 2ZXWA 3QJRA 4G7RA 4G70A 2EIKA 1FFTA 3FYIA 4GP4A 4N4YA 4G7SA 3ABLA 3EH4A 1M57A 3QJQA 3OMAA 1EHKA 3AG1A 3QJTA 4G71A 1AR1A 2GSMA 1OCCA 5DJQA 3ASOA 3OM3A 1V55A 3EHBA 3WFBB 2EINA 4GP8A 3S3CA 4G72A 3DTUA 4XYDA 5B3SA 3OMIA 4GP5A 3S3DA 3AG3A 3ABKA 2QPDA 5B1BA 3S3BA 4FA7A
chains in the Genus database with same CATH superfamily
3QJUA 2DYSA 3O0RB 3AYGA 1XMEA 3AG4A 1QLEA 3BVDA 1OCRA 2YEVA 3S8GA 2Y69A 2EIJA 3QJVA 3HB3A 3QJSA 1OCZA 3MK7A 3EH5A 3AG2A 3OMNA 3WFCB 3ASNA 2EILA 3WG7A 4G7QA 4FAAA 1OCOA 2EIMA 3AYFA 3ABMA 1V54A 5B1AA 2OCCA 3WFDB 3EH3A 3FYEA 3X2QA 2DYRA 2QPEA 5IY5A 1M56A 3S8FA 3WFEB 2ZXWA 3QJRA 4G7RA 4G70A 2EIKA 1FFTA 3FYIA 4GP4A 4N4YA 4G7SA 3ABLA 3EH4A 1M57A 3QJQA 3OMAA 1EHKA 3AG1A 3QJTA 4G71A 1AR1A 2GSMA 1OCCA 5DJQA 3ASOA 3OM3A 1V55A 3EHBA 3WFBB 2EINA 4GP8A 3S3CA 4G72A 3DTUA 4XYDA 5B3SA 3OMIA 4GP5A 3S3DA 3AG3A 3ABKA 2QPDA 5B1BA 3S3BA 4FA7A
chains in the Genus database with same CATH topology
3QJUA 2DYSA 3O0RB 3AYGA 1XMEA 3AG4A 1QLEA 3BVDA 1OCRA 2YEVA 3S8GA 2Y69A 2EIJA 3QJVA 3HB3A 3QJSA 1OCZA 3MK7A 3EH5A 3AG2A 3OMNA 3WFCB 3ASNA 2EILA 3WG7A 4G7QA 4FAAA 1OCOA 2EIMA 3AYFA 3ABMA 1V54A 5B1AA 2OCCA 3WFDB 3EH3A 3FYEA 3X2QA 2DYRA 2QPEA 5IY5A 1M56A 3S8FA 3WFEB 2ZXWA 3QJRA 4G7RA 4G70A 2EIKA 1FFTA 3FYIA 4GP4A 4N4YA 4G7SA 3ABLA 3EH4A 1M57A 3QJQA 3OMAA 1EHKA 3AG1A 3QJTA 4G71A 1AR1A 2GSMA 1OCCA 5DJQA 3ASOA 3OM3A 1V55A 3EHBA 3WFBB 2EINA 4GP8A 3S3CA 4G72A 3DTUA 4XYDA 5B3SA 3OMIA 4GP5A 3S3DA 3AG3A 3ABKA 2QPDA 5B1BA 3S3BA 4FA7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QJU A;  2DYS A;  3O0R B;  3AYG A;  1XME A;  3AG4 A;  1QLE A;  3BVD A;  1OCR A;  2YEV A;  3S8G A;  2Y69 A;  2EIJ A;  3QJV A;  3HB3 A;  3QJS A;  1OCZ A;  3MK7 A;  3EH5 A;  3AG2 A;  3OMN A;  3WFC B;  3ASN A;  2EIL A;  3WG7 A;  4G7Q A;  4FAA A;  1OCO A;  2EIM A;  3AYF A;  3ABM A;  1V54 A;  5B1A A;  2OCC A;  3WFD B;  3EH3 A;  3FYE A;  3X2Q A;  2DYR A;  2QPE A;  5IY5 A;  1M56 A;  3S8F A;  3WFE B;  2ZXW A;  3QJR A;  4G7R A;  4G70 A;  2EIK A;  1FFT A;  3FYI A;  4GP4 A;  4N4Y A;  4G7S A;  3ABL A;  3EH4 A;  1M57 A;  3QJQ A;  3OMA A;  1EHK A;  3AG1 A;  3QJT A;  4G71 A;  1AR1 A;  2GSM A;  1OCC A;  5DJQ A;  3ASO A;  3OM3 A;  1V55 A;  3EHB A;  3WFB B;  2EIN A;  4GP8 A;  3S3C A;  4G72 A;  3DTU A;  4XYD A;  5B3S A;  3OMI A;  4GP5 A;  3S3D A;  3AG3 A;  3ABK A;  2QPD A;  5B1B A;  3S3B A;  4FA7 A; 
#chains in the Genus database with same CATH topology
 3QJU A;  2DYS A;  3O0R B;  3AYG A;  1XME A;  3AG4 A;  1QLE A;  3BVD A;  1OCR A;  2YEV A;  3S8G A;  2Y69 A;  2EIJ A;  3QJV A;  3HB3 A;  3QJS A;  1OCZ A;  3MK7 A;  3EH5 A;  3AG2 A;  3OMN A;  3WFC B;  3ASN A;  2EIL A;  3WG7 A;  4G7Q A;  4FAA A;  1OCO A;  2EIM A;  3AYF A;  3ABM A;  1V54 A;  5B1A A;  2OCC A;  3WFD B;  3EH3 A;  3FYE A;  3X2Q A;  2DYR A;  2QPE A;  5IY5 A;  1M56 A;  3S8F A;  3WFE B;  2ZXW A;  3QJR A;  4G7R A;  4G70 A;  2EIK A;  1FFT A;  3FYI A;  4GP4 A;  4N4Y A;  4G7S A;  3ABL A;  3EH4 A;  1M57 A;  3QJQ A;  3OMA A;  1EHK A;  3AG1 A;  3QJT A;  4G71 A;  1AR1 A;  2GSM A;  1OCC A;  5DJQ A;  3ASO A;  3OM3 A;  1V55 A;  3EHB A;  3WFB B;  2EIN A;  4GP8 A;  3S3C A;  4G72 A;  3DTU A;  4XYD A;  5B3S A;  3OMI A;  4GP5 A;  3S3D A;  3AG3 A;  3ABK A;  2QPD A;  5B1B A;  3S3B A;  4FA7 A; 
#chains in the Genus database with same CATH homology
 3QJU A;  2DYS A;  3O0R B;  3AYG A;  1XME A;  3AG4 A;  1QLE A;  3BVD A;  1OCR A;  2YEV A;  3S8G A;  2Y69 A;  2EIJ A;  3QJV A;  3HB3 A;  3QJS A;  1OCZ A;  3MK7 A;  3EH5 A;  3AG2 A;  3OMN A;  3WFC B;  3ASN A;  2EIL A;  3WG7 A;  4G7Q A;  4FAA A;  1OCO A;  2EIM A;  3AYF A;  3ABM A;  1V54 A;  5B1A A;  2OCC A;  3WFD B;  3EH3 A;  3FYE A;  3X2Q A;  2DYR A;  2QPE A;  5IY5 A;  1M56 A;  3S8F A;  3WFE B;  2ZXW A;  3QJR A;  4G7R A;  4G70 A;  2EIK A;  1FFT A;  3FYI A;  4GP4 A;  4N4Y A;  4G7S A;  3ABL A;  3EH4 A;  1M57 A;  3QJQ A;  3OMA A;  1EHK A;  3AG1 A;  3QJT A;  4G71 A;  1AR1 A;  2GSM A;  1OCC A;  5DJQ A;  3ASO A;  3OM3 A;  1V55 A;  3EHB A;  3WFB B;  2EIN A;  4GP8 A;  3S3C A;  4G72 A;  3DTU A;  4XYD A;  5B3S A;  3OMI A;  4GP5 A;  3S3D A;  3AG3 A;  3ABK A;  2QPD A;  5B1B A;  3S3B A;  4FA7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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