5C50B

Crystal structure of the complex of human atg101-atg13 horma domain
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
Knots found
sequence length
185
structure length
185
Chain Sequence
SDLDKFIKFFALKTVQVIVQARLGEKICTRSSSSPTGSDWFNLAIKDIPEVTHEAKKALAGQLPAVGRSMCVEISLKTSEGDSMELEIWCLEMNEKCDKEIKVSYTVYNRLSLLLKSLLAITRVTPAYRLSRKQGHEYVILYRIYFGEVQLSGLGEGFQTVRVGTVGTPVGTITLSCAYRINLAF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Human Atg13-Atg101 HORMA Heterodimer: an Interaction Hub within the ULK1 Complex.
pubmed doi rcsb
molecule keywords Autophagy-related protein 101
molecule tags Protein binding
source organism Homo sapiens
total genus 46
structure length 185
sequence length 185
other databases KnotProt 2.0: S +31
ec nomenclature
pdb deposition date 2015-06-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF10033 ATG13 Autophagy-related protein 13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.900.10 Alpha Beta 2-Layer Sandwich Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A HORMA domain 5c50B00
4TZLA 2QYFA 4TRKA 4EXTC 1DUJA 2V64D 4TZMA 4TZSA 4TZOA 3ABEC 1GO4A 4GK5A 4J2GA 4TZNA 3GMHA 2V64A 4GK0A 4AEZB 4TZQA 1KLQA 5LCWZ 2VFXA 4TZJA 1S2HA 4YK8B 5C50B 3ABDA 3VU7C 4FJOC
chains in the Genus database with same CATH superfamily
4TZLA 2QYFA 4TRKA 4EXTC 1DUJA 2V64D 4TZMA 4TZSA 4TZOA 3ABEC 1GO4A 4GK5A 4J2GA 4TZNA 2QYFB 3GMHA 2V64A 4GK0A 4AEZB 4TZQA 1KLQA 5LCWZ 2VFXA 4TZJA 1S2HA 4YK8B 5C50B 3ABDA 3VU7C 4FJOC
chains in the Genus database with same CATH topology
4TZLA 2QYFA 4TRKA 4EXTC 1DUJA 2V64D 4TZMA 4TZSA 4TZOA 3ABEC 1GO4A 4GK5A 4J2GA 4TZNA 3GMHA 2V64A 4GK0A 4AEZB 4TZQA 1KLQA 5LCWZ 2VFXA 4TZJA 1S2HA 4YK8B 5C50B 3ABDA 3VU7C 4FJOC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TZL A;  2QYF A;  4TRK A;  4EXT C;  1DUJ A;  2V64 D;  4TZM A;  4TZS A;  4TZO A;  3ABE C;  1GO4 A;  4GK5 A;  4J2G A;  4TZN A;  3GMH A;  2V64 A;  4GK0 A;  4AEZ B;  4TZQ A;  1KLQ A;  5LCW Z;  2VFX A;  4TZJ A;  1S2H A;  4YK8 B;  5C50 B;  3ABD A;  3VU7 C;  4FJO C; 
#chains in the Genus database with same CATH topology
 4TZL A;  2QYF A;  4TRK A;  4EXT C;  1DUJ A;  2V64 D;  4TZM A;  4TZS A;  4TZO A;  3ABE C;  1GO4 A;  4GK5 A;  4J2G A;  4TZN A;  2QYF B;  3GMH A;  2V64 A;  4GK0 A;  4AEZ B;  4TZQ A;  1KLQ A;  5LCW Z;  2VFX A;  4TZJ A;  1S2H A;  4YK8 B;  5C50 B;  3ABD A;  3VU7 C;  4FJO C; 
#chains in the Genus database with same CATH homology
 4TZL A;  2QYF A;  4TRK A;  4EXT C;  1DUJ A;  2V64 D;  4TZM A;  4TZS A;  4TZO A;  3ABE C;  1GO4 A;  4GK5 A;  4J2G A;  4TZN A;  3GMH A;  2V64 A;  4GK0 A;  4AEZ B;  4TZQ A;  1KLQ A;  5LCW Z;  2VFX A;  4TZJ A;  1S2H A;  4YK8 B;  5C50 B;  3ABD A;  3VU7 C;  4FJO C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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