5CKXC

Non-covalent complex of dahp synthase and chorismate mutase from mycobacterium tuberculosis with bound transition state analog and feedback effectors tyrosine and phenylalanine
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
78
structure length
78
Chain Sequence
EIDTLREEIDRLDAEILALVKRRAEVSKAIGKARMASGGTRLVHSREMKVIERYSELGPDGKDLAILLLRLGRGRLGH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Remote Control by Inter-Enzyme Allostery: A Novel Paradigm for Regulation of the Shikimate Pathway.
pubmed doi rcsb
molecule tags Transferase/isomerase
source organism Mycobacterium tuberculosis (strain atcc 25618 / h37rv)
molecule keywords Phospho-2-dehydro-3-deoxyheptonate aldolase AroG
total genus 30
structure length 78
sequence length 78
chains with identical sequence D
ec nomenclature ec 5.4.99.5: Chorismate mutase.
pdb deposition date 2015-07-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01817 CM_2 Chorismate mutase type II
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.59.10 Mainly Alpha Up-down Bundle Chorismate Mutase Domain, subunit A Chorismate mutase 5ckxC00
3RETA 3HGWA 2W19C 2D8DA 2VKLA 3NVTA 1YBZA 2H9CA 1ECMA 2QBVA 2D8EA 2GTVX 2H9DA 3TFCA 3HGXA 3RMIA 2W1AC 5CKXC 3REMA
chains in the Genus database with same CATH superfamily
3RETA 3HGWA 2W19C 2D8DA 2VKLA 3NVTA 3A2KA 2E89A 1YBZA 2H9CA 1ECMA 2QBVA 1NI5A 2D8EA 2GTVX 2H9DA 3TFCA 3HGXA 2E21A 3RMIA 1WY5A 2W1AC 5CKXC 3REMA
chains in the Genus database with same CATH topology
3RETA 3HGWA 2W19C 2D8DA 2VKLA 3NVTA 1YBZA 2H9CA 1ECMA 2QBVA 2D8EA 2GTVX 2H9DA 3TFCA 3HGXA 3RMIA 2W1AC 5CKXC 3REMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RET A;  3HGW A;  2W19 C;  2D8D A;  2VKL A;  3NVT A;  1YBZ A;  2H9C A;  1ECM A;  2QBV A;  2D8E A;  2GTV X;  2H9D A;  3TFC A;  3HGX A;  3RMI A;  2W1A C;  5CKX C;  3REM A; 
#chains in the Genus database with same CATH topology
 3RET A;  3HGW A;  2W19 C;  2D8D A;  2VKL A;  3NVT A;  3A2K A;  2E89 A;  1YBZ A;  2H9C A;  1ECM A;  2QBV A;  1NI5 A;  2D8E A;  2GTV X;  2H9D A;  3TFC A;  3HGX A;  2E21 A;  3RMI A;  1WY5 A;  2W1A C;  5CKX C;  3REM A; 
#chains in the Genus database with same CATH homology
 3RET A;  3HGW A;  2W19 C;  2D8D A;  2VKL A;  3NVT A;  1YBZ A;  2H9C A;  1ECM A;  2QBV A;  2D8E A;  2GTV X;  2H9D A;  3TFC A;  3HGX A;  3RMI A;  2W1A C;  5CKX C;  3REM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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