5B1AA

Bovine heart cytochrome c oxidase in the fully oxidized state at 1.5 angstrom resolution
Total Genus 207
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
207
sequence length
513
structure length
513
Chain Sequence
FINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Mg2+-containing Water Cluster of Mammalian Cytochrome c Oxidase Collects Four Pumping Proton Equivalents in Each Catalytic Cycle.
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Cytochrome c oxidase subunit 1
total genus 207
structure length 513
sequence length 513
chains with identical sequence N
ec nomenclature ec 1.9.3.1: Cytochrome-c oxidase.
pdb deposition date 2015-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00115 COX1 Cytochrome C and Quinol oxidase polypeptide I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase; Chain A Cytochrome c oxidase-like, subunit I domain 5b1aA00
1OCRA 3ASNA 3S8FA 3WFEB 1QLEA 3WFBB 1OCCA 3OMNA 5B1BA 4G7RA 3EH4A 3WG7A 3ABMA 2QPEA 4G71A 1M57A 3BVDA 1V55A 2EIKA 4GP5A 3ABLA 2ZXWA 3EHBA 1V54A 1OCOA 5B3SA 4FA7A 5DJQA 3EH5A 3FYEA 4G7SA 3O0RB 3ABKA 4GP4A 3QJTA 2DYRA 3HB3A 4G7QA 2DYSA 2EILA 1EHKA 3S3BA 1AR1A 3AG4A 3OMAA 5B1AA 3QJSA 3S3CA 2QPDA 3WFCB 2GSMA 4GP8A 3QJQA 3QJUA 4N4YA 2EINA 3X2QA 3QJRA 3AG1A 3OM3A 3MK7A 4G70A 3EH3A 3FYIA 2YEVA 2OCCA 3QJVA 3AYFA 4G72A 3AG2A 5IY5A 4FAAA 1M56A 1XMEA 3S3DA 2Y69A 3AG3A 1FFTA 1OCZA 4XYDA 3DTUA 2EIJA 2EIMA 3ASOA 3WFDB 3S8GA 3OMIA 3AYGA
chains in the Genus database with same CATH superfamily
1OCRA 3ASNA 3S8FA 3WFEB 1QLEA 3WFBB 1OCCA 3OMNA 5B1BA 4G7RA 3EH4A 3WG7A 3ABMA 2QPEA 4G71A 1M57A 3BVDA 1V55A 2EIKA 4GP5A 3ABLA 2ZXWA 3EHBA 1V54A 1OCOA 5B3SA 4FA7A 5DJQA 3EH5A 3FYEA 4G7SA 3O0RB 3ABKA 4GP4A 3QJTA 2DYRA 3HB3A 4G7QA 2DYSA 2EILA 1EHKA 3S3BA 1AR1A 3AG4A 3OMAA 5B1AA 3QJSA 3S3CA 2QPDA 3WFCB 2GSMA 4GP8A 3QJQA 3QJUA 4N4YA 2EINA 3X2QA 3QJRA 3AG1A 3OM3A 3MK7A 4G70A 3EH3A 3FYIA 2YEVA 2OCCA 3QJVA 3AYFA 4G72A 3AG2A 5IY5A 4FAAA 1M56A 1XMEA 3S3DA 2Y69A 3AG3A 1FFTA 1OCZA 4XYDA 3DTUA 2EIJA 2EIMA 3ASOA 3WFDB 3S8GA 3OMIA 3AYGA
chains in the Genus database with same CATH topology
1OCRA 3ASNA 3S8FA 3WFEB 1QLEA 3WFBB 1OCCA 3OMNA 5B1BA 4G7RA 3EH4A 3WG7A 3ABMA 2QPEA 4G71A 1M57A 3BVDA 1V55A 2EIKA 4GP5A 3ABLA 2ZXWA 3EHBA 1V54A 1OCOA 5B3SA 4FA7A 5DJQA 3EH5A 3FYEA 4G7SA 3O0RB 3ABKA 4GP4A 3QJTA 2DYRA 3HB3A 4G7QA 2DYSA 2EILA 1EHKA 3S3BA 1AR1A 3AG4A 3OMAA 5B1AA 3QJSA 3S3CA 2QPDA 3WFCB 2GSMA 4GP8A 3QJQA 3QJUA 4N4YA 2EINA 3X2QA 3QJRA 3AG1A 3OM3A 3MK7A 4G70A 3EH3A 3FYIA 2YEVA 2OCCA 3QJVA 3AYFA 4G72A 3AG2A 5IY5A 4FAAA 1M56A 1XMEA 3S3DA 2Y69A 3AG3A 1FFTA 1OCZA 4XYDA 3DTUA 2EIJA 2EIMA 3ASOA 3WFDB 3S8GA 3OMIA 3AYGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OCR A;  3ASN A;  3S8F A;  3WFE B;  1QLE A;  3WFB B;  1OCC A;  3OMN A;  5B1B A;  4G7R A;  3EH4 A;  3WG7 A;  3ABM A;  2QPE A;  4G71 A;  1M57 A;  3BVD A;  1V55 A;  2EIK A;  4GP5 A;  3ABL A;  2ZXW A;  3EHB A;  1V54 A;  1OCO A;  5B3S A;  4FA7 A;  5DJQ A;  3EH5 A;  3FYE A;  4G7S A;  3O0R B;  3ABK A;  4GP4 A;  3QJT A;  2DYR A;  3HB3 A;  4G7Q A;  2DYS A;  2EIL A;  1EHK A;  3S3B A;  1AR1 A;  3AG4 A;  3OMA A;  5B1A A;  3QJS A;  3S3C A;  2QPD A;  3WFC B;  2GSM A;  4GP8 A;  3QJQ A;  3QJU A;  4N4Y A;  2EIN A;  3X2Q A;  3QJR A;  3AG1 A;  3OM3 A;  3MK7 A;  4G70 A;  3EH3 A;  3FYI A;  2YEV A;  2OCC A;  3QJV A;  3AYF A;  4G72 A;  3AG2 A;  5IY5 A;  4FAA A;  1M56 A;  1XME A;  3S3D A;  2Y69 A;  3AG3 A;  1FFT A;  1OCZ A;  4XYD A;  3DTU A;  2EIJ A;  2EIM A;  3ASO A;  3WFD B;  3S8G A;  3OMI A;  3AYG A; 
#chains in the Genus database with same CATH topology
 1OCR A;  3ASN A;  3S8F A;  3WFE B;  1QLE A;  3WFB B;  1OCC A;  3OMN A;  5B1B A;  4G7R A;  3EH4 A;  3WG7 A;  3ABM A;  2QPE A;  4G71 A;  1M57 A;  3BVD A;  1V55 A;  2EIK A;  4GP5 A;  3ABL A;  2ZXW A;  3EHB A;  1V54 A;  1OCO A;  5B3S A;  4FA7 A;  5DJQ A;  3EH5 A;  3FYE A;  4G7S A;  3O0R B;  3ABK A;  4GP4 A;  3QJT A;  2DYR A;  3HB3 A;  4G7Q A;  2DYS A;  2EIL A;  1EHK A;  3S3B A;  1AR1 A;  3AG4 A;  3OMA A;  5B1A A;  3QJS A;  3S3C A;  2QPD A;  3WFC B;  2GSM A;  4GP8 A;  3QJQ A;  3QJU A;  4N4Y A;  2EIN A;  3X2Q A;  3QJR A;  3AG1 A;  3OM3 A;  3MK7 A;  4G70 A;  3EH3 A;  3FYI A;  2YEV A;  2OCC A;  3QJV A;  3AYF A;  4G72 A;  3AG2 A;  5IY5 A;  4FAA A;  1M56 A;  1XME A;  3S3D A;  2Y69 A;  3AG3 A;  1FFT A;  1OCZ A;  4XYD A;  3DTU A;  2EIJ A;  2EIM A;  3ASO A;  3WFD B;  3S8G A;  3OMI A;  3AYG A; 
#chains in the Genus database with same CATH homology
 1OCR A;  3ASN A;  3S8F A;  3WFE B;  1QLE A;  3WFB B;  1OCC A;  3OMN A;  5B1B A;  4G7R A;  3EH4 A;  3WG7 A;  3ABM A;  2QPE A;  4G71 A;  1M57 A;  3BVD A;  1V55 A;  2EIK A;  4GP5 A;  3ABL A;  2ZXW A;  3EHB A;  1V54 A;  1OCO A;  5B3S A;  4FA7 A;  5DJQ A;  3EH5 A;  3FYE A;  4G7S A;  3O0R B;  3ABK A;  4GP4 A;  3QJT A;  2DYR A;  3HB3 A;  4G7Q A;  2DYS A;  2EIL A;  1EHK A;  3S3B A;  1AR1 A;  3AG4 A;  3OMA A;  5B1A A;  3QJS A;  3S3C A;  2QPD A;  3WFC B;  2GSM A;  4GP8 A;  3QJQ A;  3QJU A;  4N4Y A;  2EIN A;  3X2Q A;  3QJR A;  3AG1 A;  3OM3 A;  3MK7 A;  4G70 A;  3EH3 A;  3FYI A;  2YEV A;  2OCC A;  3QJV A;  3AYF A;  4G72 A;  3AG2 A;  5IY5 A;  4FAA A;  1M56 A;  1XME A;  3S3D A;  2Y69 A;  3AG3 A;  1FFT A;  1OCZ A;  4XYD A;  3DTU A;  2EIJ A;  2EIM A;  3ASO A;  3WFD B;  3S8G A;  3OMI A;  3AYG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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