160
|
556
|
6cgfA |
Crystal structure of hiv-1 y188l mutant reverse transcriptase in complex with non-nucleoside inhibitor k-5a2 |
164
|
556
|
6c0oA |
Crystal structure of hiv-1 k103n mutant reverse transcriptase in complex with non-nucleoside inhibitor 25a |
161
|
556
|
6c0nA |
Crystal structure of hiv-1 reverse transcriptase in complex with non-nucleoside inhibitor 25a |
160
|
556
|
6c0rA |
Crystal structure of hiv-1 k103n/y181c mutant reverse transcriptase in complex with non-nucleoside inhibitor 25a |
115
|
425
|
6c0nB |
Crystal structure of hiv-1 reverse transcriptase in complex with non-nucleoside inhibitor 25a |
162
|
556
|
6c0pA |
Crystal structure of hiv-1 e138k mutant reverse transcriptase in complex with non-nucleoside inhibitor 25a |
19
|
99
|
6bz2A |
Crystal structure of wild-type hiv-1 protease with a novel hiv-1 inhibitor grl-14213a of 6-5-5-ring fused crown-like tetrahydropyranofuran as the p2-ligand, a cyclopropylaminobenzothiazole as the p2'-ligand and 3,5-difluorophenylmethyl as the p1-ligand |
119
|
425
|
6c0kB |
Crystal structure of hiv-1 k103n mutant reverse transcriptase in complex with non-nucleoside inhibitor k-5a2 |
113
|
425
|
6c0pB |
Crystal structure of hiv-1 e138k mutant reverse transcriptase in complex with non-nucleoside inhibitor 25a |
164
|
556
|
6c0jA |
Crystal structure of hiv-1 reverse transcriptase in complex with non-nucleoside inhibitor k-5a2 |
115
|
425
|
6c0rB |
Crystal structure of hiv-1 k103n/y181c mutant reverse transcriptase in complex with non-nucleoside inhibitor 25a |
119
|
425
|
6c0oB |
Crystal structure of hiv-1 k103n mutant reverse transcriptase in complex with non-nucleoside inhibitor 25a |
115
|
425
|
6c0lB |
Crystal structure of hiv-1 e138k mutant reverse transcriptase in complex with non-nucleoside inhibitor k-5a2 |
163
|
556
|
6c0lA |
Crystal structure of hiv-1 e138k mutant reverse transcriptase in complex with non-nucleoside inhibitor k-5a2 |
165
|
556
|
6c0kA |
Crystal structure of hiv-1 k103n mutant reverse transcriptase in complex with non-nucleoside inhibitor k-5a2 |
115
|
425
|
6c0jB |
Crystal structure of hiv-1 reverse transcriptase in complex with non-nucleoside inhibitor k-5a2 |
16
|
99
|
6b3cA |
Crystal structure of hiv protease complexed with n-(3-fluoro-2-(2-((2s,6r)-6-methyl-1-(phenylsulfonyl)piperazin-2-yl)ethyl)phenyl)-3,3-bis(4-fluorophenyl)propanamide |
18
|
99
|
6b3fA |
Crystal structure of hiv protease complexed with n-(3-fluoro-2-(2-((2s,5s)-5-methyl-1-(phenylsulfonyl)piperazin-2-yl)ethyl)phenyl)-3,3-bis(4-fluorophenyl)propanamide |
18
|
99
|
6b36A |
Crystal structure of hiv protease complexed with (s)-n-(3-fluoro-2-(2-(1-(phenylsulfonyl)piperazin-2-yl)ethyl)phenyl)-3,3-bis(4-fluorophenyl)propanamide |
18
|
99
|
6b3hA |
Crystal structure of hiv protease complexed with n-(2-(2-((6r,9s)-2,2-dioxido-2-thia-1,7-diazabicyclo[4.3.1]decan-9-yl)ethyl)-3-fluorophenyl)-3,3-bis(4-fluorophenyl)propanamide |
16
|
99
|
6b38A |
Crystal structure of hiv protease complexed with n-(3-fluoro-2-(2-((2s,6r)-6-methyl-1-(phenylsulfonyl)piperazin-2-yl)ethyl)phenyl)-3,3-bis(4-fluorophenyl)propanamide |
17
|
99
|
6b3gA |
Crystal structure of hiv protease complexed with n-(3-fluoro-2-(2-((2s,6s)-6-methyl-1-(phenylsulfonyl)piperazin-2-yl)ethyl)phenyl)-3,3-bis(4-fluorophenyl)propanamide |
153
|
555
|
6aocA |
Crystal structure of an n-hydroxythienopyrimidine-2,4-dione rnase h active site inhibitor with multiple binding modes to hiv reverse transcriptase |
129
|
429
|
6aocB |
Crystal structure of an n-hydroxythienopyrimidine-2,4-dione rnase h active site inhibitor with multiple binding modes to hiv reverse transcriptase |
19
|
103
|
5yrsB |
X-ray snapshot of hiv-1 protease in action: observation of tetrahedral intermediate and its sihb with catalytic aspartate |
17
|
99
|
5yojA |
Structure of a17 hiv-1 protease in complex with inhibitor kni-1657 |
18
|
99
|
5yrsA |
X-ray snapshot of hiv-1 protease in action: observation of tetrahedral intermediate and its sihb with catalytic aspartate |
17
|
99
|
5yokA |
Structure of hiv-1 protease in complex with inhibitor kni-1657 |
127
|
550
|
5uv5A |
Crystal structure of a 2-hydroxyisoquinoline-1,3-dione rnase h active site inhibitor with multiple binding modes to hiv reverse transcriptase |
110
|
424
|
5vqqB |
Crystal structure of hiv-1 reverse transcriptase in complex with n-(6-cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)-4-methylnaphthalen-1-yl)-2-fluoro-n-methylacetamide (jlj683), a non-nucleoside inhibitor |
111
|
424
|
5vqtB |
Crystal structure of hiv-1 reverse transcriptase in complex with 2-chloro-n-(6-cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)-4-methylnaphthalen-1-yl)-n-methylacetamide (jlj686), a non-nucleoside inhibitor |
156
|
558
|
5vz6A |
Hiv reverse transcriptase complexed with (e)-3-(pyrimidin-2-yl)-n-(5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1h-pyrazol-3-yl)acrylamide |
114
|
423
|
5uv5B |
Crystal structure of a 2-hydroxyisoquinoline-1,3-dione rnase h active site inhibitor with multiple binding modes to hiv reverse transcriptase |
17
|
99
|
5vj3A |
Hiv protease (pr) in open form with mg2+ in active site and hive-9 in eye site |
111
|
424
|
5c25B |
Crystal structure of hiv-1 reverse transcriptase in complex with 6-((4-((4-cyanophenyl)amino)-1,3,5-triazin-2-yl)amino)-5,7-dimethyl-2-naphthonitrile (jlj639), a non-nucleoside inhibitor |
114
|
425
|
4r5pB |
Crystal structure of hiv-1 reverse transcriptase (rt) with dna and a nucleoside triphosphate mimic alpha-carboxy nucleoside phosphonate inhibitor |
120
|
412
|
5c24B |
Crystal structure of hiv-1 reverse transcriptase in complex with 7-((4-((4-cyanophenyl)amino)-1,3,5-triazin-2-yl)amino)-6,8-dimethylindolizine-2-carbonitrile (jlj605), a non-nucleoside inhibitor |
147
|
554
|
5c25A |
Crystal structure of hiv-1 reverse transcriptase in complex with 6-((4-((4-cyanophenyl)amino)-1,3,5-triazin-2-yl)amino)-5,7-dimethyl-2-naphthonitrile (jlj639), a non-nucleoside inhibitor |
131
|
547
|
5c42A |
Crystal structure of hiv-1 reverse transcriptase (k101p) variant in complex with 8-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)indolizine-2-carbonitrile (jlj555), a non-nucleoside inhibitor |
100
|
424
|
5c42B |
Crystal structure of hiv-1 reverse transcriptase (k101p) variant in complex with 8-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)indolizine-2-carbonitrile (jlj555), a non-nucleoside inhibitor |
18
|
99
|
5bs4A |
Hiv-1 wild type protease with grl-047-11a (a methylamine bis-tetrahydrofuran p2-ligand, 4-amino sulfonamide derivative) |
18
|
99
|
5bryA |
Hiv-1 wild type protease with grl-011-11a (a methylamine bis-tetrahydrofuran p2-ligand, sulfonamide isostere derivate) |
143
|
553
|
4zhrA |
Structure of hiv-1 rt q151m mutant |
114
|
427
|
4zhrB |
Structure of hiv-1 rt q151m mutant |
18
|
99
|
4zipA |
Hiv-1 wild type protease with grl-0648a (a isophthalamide-derived p2-ligand) |
18
|
99
|
4zlsA |
Hiv-1 wild type protease with grl-096-13a (a boc-derivative p2-ligand, 3,-5-dimethylbiphenyl p1-ligand) |
19
|
99
|
4qjaA |
Crystal structure of inactive hiv-1 protease in complex with p1-p6 substrate variant (p453l) |
45
|
203
|
4qlhA |
Crystal structure of drug resistant v82s/v1082s hiv-1 protease |
44
|
203
|
4ep3A |
Crystal structure of inactive single chain wild-type hiv-1 protease in complex with the substrate ca-p2 |
18
|
99
|
4f76A |
Crystal structure of the active hiv-1 protease in complex with the products of p1-p6 substrate |