1AVVA

Hiv-1 nef protein, unliganded core domain
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
130
structure length
99
Chain Sequence
VPLRPMTYKAAVDLSHFLKEKGGLEGLIHSQRRQDILDLWIYHTQGYFPDWQNYTPGPGVRYPLTFGWCYKLVPEVLEWRFDSRLAFHHVARELHPEYF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Myristylation
molecule keywords NEGATIVE FACTOR
publication title The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling.
pubmed doi rcsb
source organism Human immunodeficiency virus 1
total genus 24
structure length 99
sequence length 130
ec nomenclature
pdb deposition date 1997-09-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.62.10 Alpha Beta 2-Layer Sandwich Nef Regulatory Factor Nef Regulatory Factor 1avvA00
2XI1B 2XI1A 3REBA 4EMZB 3IK5A 1EFNB 2NEFA 4EN2B 4NEEC 1AVVA 4U5WA 1AVZA 3RBBA 3REAA 3IOZA 4ORZB 4D8DB
chains in the Genus database with same CATH superfamily
2XI1B 2XI1A 3REBA 4EMZB 3IK5A 1EFNB 2NEFA 4EN2B 4NEEC 1AVVA 4U5WA 1AVZA 3RBBA 3REAA 3IOZA 4ORZB 4D8DB
chains in the Genus database with same CATH topology
2XI1B 2XI1A 3REBA 4EMZB 3IK5A 1EFNB 2NEFA 4EN2B 4NEEC 1AVVA 4U5WA 1AVZA 3RBBA 3REAA 3IOZA 4ORZB 4D8DB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XI1 B;  2XI1 A;  3REB A;  4EMZ B;  3IK5 A;  1EFN B;  2NEF A;  4EN2 B;  4NEE C;  1AVV A;  4U5W A;  1AVZ A;  3RBB A;  3REA A;  3IOZ A;  4ORZ B;  4D8D B; 
#chains in the Genus database with same CATH topology
 2XI1 B;  2XI1 A;  3REB A;  4EMZ B;  3IK5 A;  1EFN B;  2NEF A;  4EN2 B;  4NEE C;  1AVV A;  4U5W A;  1AVZ A;  3RBB A;  3REA A;  3IOZ A;  4ORZ B;  4D8D B; 
#chains in the Genus database with same CATH homology
 2XI1 B;  2XI1 A;  3REB A;  4EMZ B;  3IK5 A;  1EFN B;  2NEF A;  4EN2 B;  4NEE C;  1AVV A;  4U5W A;  1AVZ A;  3RBB A;  3REA A;  3IOZ A;  4ORZ B;  4D8D B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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