3RBBA

Hiv-1 nef protein in complex with engineered hck sh3 domain
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
137
structure length
137
Chain Sequence
FPVRPQVPLRPMTYKAALDISHFLKEKGGLEGLIWSQRRQEILDLWIYHTQGYFPDWQNYTPGPGIRYPLTFGWCFKLVPVEPEKVEEANEGENNSLLHPMSLHGMEDAEKEVLVWRFDSKLAFHHMARELHPEYYK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Viral protein, protein binding
molecule keywords Protein Nef
publication title Conformation of the Dileucine-Based Sorting Motif in HIV-1 Nef Revealed by Intermolecular Domain Assembly.
pubmed doi rcsb
source organism Hiv-1 m:b_arv2/sf2
total genus 34
structure length 137
sequence length 137
chains with identical sequence C
ec nomenclature
pdb deposition date 2011-03-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.62.10 Alpha Beta 2-Layer Sandwich Nef Regulatory Factor Nef Regulatory Factor 3rbbA00
3REAA 3REBA 4D8DB 1AVVA 3RBBA 3IK5A 2XI1A 1AVZA 2NEFA 1EFNB 4EN2B 4EMZB 4U5WA 3IOZA 4NEEC 2XI1B 4ORZB
chains in the Genus database with same CATH superfamily
3REAA 3REBA 4D8DB 1AVVA 3RBBA 3IK5A 2XI1A 1AVZA 2NEFA 1EFNB 4EN2B 4EMZB 4U5WA 3IOZA 4NEEC 2XI1B 4ORZB
chains in the Genus database with same CATH topology
3REAA 3REBA 4D8DB 1AVVA 3RBBA 3IK5A 2XI1A 1AVZA 2NEFA 1EFNB 4EN2B 4EMZB 4U5WA 3IOZA 4NEEC 2XI1B 4ORZB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3REA A;  3REB A;  4D8D B;  1AVV A;  3RBB A;  3IK5 A;  2XI1 A;  1AVZ A;  2NEF A;  1EFN B;  4EN2 B;  4EMZ B;  4U5W A;  3IOZ A;  4NEE C;  2XI1 B;  4ORZ B; 
#chains in the Genus database with same CATH topology
 3REA A;  3REB A;  4D8D B;  1AVV A;  3RBB A;  3IK5 A;  2XI1 A;  1AVZ A;  2NEF A;  1EFN B;  4EN2 B;  4EMZ B;  4U5W A;  3IOZ A;  4NEE C;  2XI1 B;  4ORZ B; 
#chains in the Genus database with same CATH homology
 3REA A;  3REB A;  4D8D B;  1AVV A;  3RBB A;  3IK5 A;  2XI1 A;  1AVZ A;  2NEF A;  1EFN B;  4EN2 B;  4EMZ B;  4U5W A;  3IOZ A;  4NEE C;  2XI1 B;  4ORZ B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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