2NEFA

Hiv-1 nef (regulatory factor), nmr, 40 structures
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
136
structure length
136
Chain Sequence
AWLEAQEEEEVGFPVTPQVPLRPMTYKAAVDLSHFLKEKGGLEGLIHSQRRQDILDLWIYHTQGYFPDWQNYTPGPGIRYPLTFGWCYKLVPVEPEKLEEANKDDPEREVLEWRFDSRLAFHHMARELHPEYFKNA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Regulatory factor
molecule keywords NEGATIVE FACTOR (F-PROTEIN)
publication title Refined solution structure and backbone dynamics of HIV-1 Nef.
pubmed rcsb
source organism Human immunodeficiency virus type 1
total genus 18
structure length 136
sequence length 136
ec nomenclature
pdb deposition date 1997-02-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.62.10 Alpha Beta 2-Layer Sandwich Nef Regulatory Factor Nef Regulatory Factor 2nefA00
4EN2B 2NEFA 2XI1B 4NEEC 3RBBA 2XI1A 4D8DB 1AVZA 4ORZB 1AVVA 4U5WA 1EFNB 3IOZA 3IK5A 4EMZB 3REAA 3REBA
chains in the Genus database with same CATH superfamily
4EN2B 2NEFA 2XI1B 4NEEC 3RBBA 2XI1A 4D8DB 1AVZA 4ORZB 1AVVA 4U5WA 1EFNB 3IOZA 3IK5A 4EMZB 3REAA 3REBA
chains in the Genus database with same CATH topology
4EN2B 2NEFA 2XI1B 4NEEC 3RBBA 2XI1A 4D8DB 1AVZA 4ORZB 1AVVA 4U5WA 1EFNB 3IOZA 3IK5A 4EMZB 3REAA 3REBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EN2 B;  2NEF A;  2XI1 B;  4NEE C;  3RBB A;  2XI1 A;  4D8D B;  1AVZ A;  4ORZ B;  1AVV A;  4U5W A;  1EFN B;  3IOZ A;  3IK5 A;  4EMZ B;  3REA A;  3REB A; 
#chains in the Genus database with same CATH topology
 4EN2 B;  2NEF A;  2XI1 B;  4NEE C;  3RBB A;  2XI1 A;  4D8D B;  1AVZ A;  4ORZ B;  1AVV A;  4U5W A;  1EFN B;  3IOZ A;  3IK5 A;  4EMZ B;  3REA A;  3REB A; 
#chains in the Genus database with same CATH homology
 4EN2 B;  2NEF A;  2XI1 B;  4NEE C;  3RBB A;  2XI1 A;  4D8D B;  1AVZ A;  4ORZ B;  1AVV A;  4U5W A;  1EFN B;  3IOZ A;  3IK5 A;  4EMZ B;  3REA A;  3REB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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