1AVZA

V-1 nef protein in complex with wild type fyn sh3 domain
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
130
structure length
100
Chain Sequence
VPLRPMTYKAAVDLSHFLKEKGGLEGLIHSQRRQDILDLWIYHTQGYFPDWQNYTPGPGVRYPLTFGWCYKLVPVEVLEWRFDSRLAFHHVARELHPEYF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Complex (myristylation/transferase)
molecule keywords NEGATIVE FACTOR
publication title The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling.
pubmed doi rcsb
source organism Human immunodeficiency virus 1
total genus 29
structure length 100
sequence length 130
chains with identical sequence B
ec nomenclature
pdb deposition date 1997-09-23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.62.10 Alpha Beta 2-Layer Sandwich Nef Regulatory Factor Nef Regulatory Factor 1avzA00
4EN2B 3IOZA 4EMZB 3IK5A 4U5WA 3REAA 2XI1A 2XI1B 3RBBA 1EFNB 1AVZA 1AVVA 4D8DB 3REBA 4NEEC 2NEFA 4ORZB
chains in the Genus database with same CATH superfamily
4EN2B 3IOZA 4EMZB 3IK5A 4U5WA 3REAA 2XI1A 2XI1B 3RBBA 1EFNB 1AVZA 1AVVA 4D8DB 3REBA 4NEEC 2NEFA 4ORZB
chains in the Genus database with same CATH topology
4EN2B 3IOZA 4EMZB 3IK5A 4U5WA 3REAA 2XI1A 2XI1B 3RBBA 1EFNB 1AVZA 1AVVA 4D8DB 3REBA 4NEEC 2NEFA 4ORZB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EN2 B;  3IOZ A;  4EMZ B;  3IK5 A;  4U5W A;  3REA A;  2XI1 A;  2XI1 B;  3RBB A;  1EFN B;  1AVZ A;  1AVV A;  4D8D B;  3REB A;  4NEE C;  2NEF A;  4ORZ B; 
#chains in the Genus database with same CATH topology
 4EN2 B;  3IOZ A;  4EMZ B;  3IK5 A;  4U5W A;  3REA A;  2XI1 A;  2XI1 B;  3RBB A;  1EFN B;  1AVZ A;  1AVV A;  4D8D B;  3REB A;  4NEE C;  2NEF A;  4ORZ B; 
#chains in the Genus database with same CATH homology
 4EN2 B;  3IOZ A;  4EMZ B;  3IK5 A;  4U5W A;  3REA A;  2XI1 A;  2XI1 B;  3RBB A;  1EFN B;  1AVZ A;  1AVV A;  4D8D B;  3REB A;  4NEE C;  2NEF A;  4ORZ B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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